Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEPiperazinemalateCat.No.:HY-B0912BCASNo.:14852-14-3Synonyms:1,4-Diazacyclohexanemalate分?式:C?H??N?O?分?量:220.22作?靶點(diǎn):Parasite作?通路:Anti-infection儲(chǔ)存?式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實(shí)驗(yàn)H2O:≥100mg/mL(454.09mM)*"≥"meanssoluble,butsaturationunknown.MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM4.5409mL22.7046mL45.4091mL5mM0.9082mL4.5409mL9.0818mL10mM0.4541mL2.2705mL4.5409mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。BIOLOGICALACTIVITY?物活性Piperazinehexahydrate?種驅(qū)除腸內(nèi)寄??的藥。體外研究Piperazine(0.01-0.1mM)slightlyinhibitsnematodesdevelopmentcomparedtocontrol.Piperazine(1μM)1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEreducesthetotalbroodsizeofthenematodes.Piperazineincreasesthethepercentageofzebrafishwithdevelopmentaldelayinadose-dependentmanner[1].PiperazineisattractivesolventforCO2capture,andthefacilePiperazineliberationmaycontributetoitsrelativelyhighCO2absorptionrate[2].REFERENCES[1].RaczPI,etal.ApplicationofCaenorhabditiselegans(nematode)andDaniorerioembryo(zebrafish)asmodelsystemstoscreenfordevelopmentalandreproductivetoxicityofPiperazinecompounds.ToxicolInVitro.2017Oct;44:11-16.[2].StoweHM,etal.First-principlesassessmentofCO2capturemechanismsinaqueouspiperazinesolution.PhysChemChemPhys.2016Sep14;18(36):25296-25307.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-58