兒童青少年精神分裂癥的藥物治療,參 考 文 獻,中華醫(yī)學會精神病學分會. 精神分裂癥防治指南（第二版）.2015.(140).精神病學（第五版）American Academy of Child and Adolescent Psychiatry. Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry. 2013 Sep;52(9):976-90.Howes OD, et al. Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology. Am J Psychiatry. 2016 Dec 6:appiajp201616050503.Hiemke C, Baumann P, Bergemann N,等. AGNP精神科治療藥物監(jiān)測共識指南:2011J. 實用藥物與臨床, 2016, 19(10).Correll C U, Manu P, Olshanskiy V, et al. Cardiometabolic Risk of Second-Generation Antipsychotics During First-Time Use in Children and AdolescentsJ. Jama the Journal of the American Medical Association, 2009, 302(16):1765-1773.,定 義,兒童青少年精神分裂：起病年齡18歲的一種病因未明，臨床上以基本個性改變、特征性思維障礙、感知覺異常、情感與環(huán)境不協(xié)調(diào)、孤獨性表現(xiàn)為主要特征的精神障礙。兒童青少年精神分裂癥分為：起病年齡1318歲的早發(fā)性精神分裂癥起病年齡13歲的兒童期發(fā)病的精神分裂。兒童青少年精神分裂癥的診斷，與成人相同，不考慮發(fā)病年齡。,American Academy of Child and Adolescent Psychiatry. Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry. 2013 Sep;52(9):976-90.,兒童青少年期抗精神病藥物使用現(xiàn)狀,中華醫(yī)學會精神病學分會. 精神分裂癥防治指南（第二版）.2015.(140).American Academy of Child and Adolescent Psychiatry. Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry. 2013 Sep;52(9):976-90.,選 藥 原 則,中華醫(yī)學會精神病學分會. 精神分裂癥防治指南（第二版）.2015.(140).American Academy of Child and Adolescent Psychiatry. Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry. 2013 Sep;52(9):976-90.,2016年12月6日AJP發(fā)表的難治性精神分裂癥標準,Howes OD, et al. Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology. Am J Psychiatry. 2016 Dec 6:appiajp201616050503.,相 互 作 用,Hiemke C, Baumann P, Bergemann N,等. AGNP精神科治療藥物監(jiān)測共識指南:2011J. 實用藥物與臨床, 2016, 19(10).,藥 物 不 良 反 應,中華醫(yī)學會精神病學分會. 精神分裂癥防治指南（第二版）.2015.(140).American Academy of Child and Adolescent Psychiatry. Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry. 2013 Sep;52(9):976-90.,代 謝 紊 亂,Correll C U, Manu P, Olshanskiy V, et al. Cardiometabolic Risk of Second-Generation Antipsychotics During First-Time Use in Children and AdolescentsJ. Jama the Journal of the American Medical Association, 2009, 302(16):1765-1773.,代 謝 紊 亂,Correll C U, Manu P, Olshanskiy V, et al. Cardiometabolic Risk of Second-Generation Antipsychotics During First-Time Use in Children and AdolescentsJ. Jama the Journal of the American Medical Association, 2009, 302(16):1765-1773.,代 謝 紊 亂,American Academy of Child and Adolescent Psychiatry. Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry. 2013 Sep;52(9):976-90.,EPS 副作用,中華醫(yī)學會精神病學分會. 精神分裂癥防治指南（第二版）.2015.(140).American Academy of Child and Adolescent Psychiatry. Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry. 2013 Sep;52(9):976-90.,其 他 ADR,中華醫(yī)學會精神病學分會. 精神分裂癥防治指南（第二版）.2015.(140).American Academy of Child and Adolescent Psychiatry. Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry. 2013 Sep;52(9