其Long-term Tight

AntigenprocessingandGapAxonECM-receptor

GnRHsignaling

TcellreceptorsignalingComplementandcoagulationcascadesCalciumsignalingpathBwacyellreceptorsignalingpathwayPhosphatidylinositolsignalingsystFeomcalErbBsignalingCytokine-cytokinereceptor

AllograftToll-likereceptorsignalingWntsignaling

Cell TGFbetasignaling

Jak-STATsignalingInsulinsignaling Adipocytokinesignaling p53signalingDiffgeneSig

Cytokine-cytokinereceptor ChemokinesignalingMAPKCytokine-cytokinereceptor ChemokinesignalingMAPKsignalingOlfactorytransductionHematopoieticcelllineageTcellreceptorsignalingpathwayPathwaysincancerFc Jak-STATsignalingpathwaySystemiclupuserythematosusTGF-betasignalingpathwayComplementandcoagulationCytokine-cytokinereceptor ProteinprocessinginendosmicHipposignaling9TranscriptionalmisregulationinJak-STATsignaling8Hepatitis5Celladhesionmolecules87Exp-49257-14-89-45-6312-4221218-?[1]YuS,LongJ,YuJ,DuJ,MaP,MaY,etal.ysisofdi?erentiationpotentialsandgeneexpressionpro?lesofmesenchymalstemcellsderivedfromperiodontalligamentandWharton'sjellyoftheumbilicalcord.CellsTissuesOrgans2013;197:209-23.?[2]XuD,YangF,YuanJH,ZhangL,BiHS,ZhouCC,etal.LncRNA-LALR1accelerateshepatocyteproliferationduringliverregenerationbyactivatingWnt/beta-Cateninsignaling.Hepatology2013:n/a-n/a.?[3]QinB,HuangF,LiangY,YangZ,ZhongR.ysisofalteredmicroRNAexpressionpro?lesinperipheralbloodmononuclearcellsfrompatientswithprimarybiliarycirrhosis.JGastroenterolHepatol2013;28:543-50.?[4]HeM,WangQY,YinQQ,TangJ,LuY,ZhouCX,etal.HIF-1alphadownregulatesmiR-17/20adirectlyp21andSTAT3:aroleinmyeloidleukemiccelldi?erentiation.CellDeathDi?er2013;20:408-?[5]BaoY,LinC,RenJ,LiuJ.MicroRNA-384-5pregulatesischemia-inducedcardioprotectionbytargetingphosphatidylinositol-4,5-bisphosphate3-kinase,catalyticsubunitdelta(PI3Kp110delta).Apoptosis2013;18:260-?[6]ZhangX,YeL,HuJ,TangW,LiuR,YangM,etal.Acuteresponseofperipheralbloodcelltoautologoushematopoieticstemcelltransntationintype1diabeticpatient.PLoSOne2012;7:e31887.?[7]ZhangP,MaY,WangF,YangJ,LiuZ,PengJ,etal.ComprehensivegeneandmicroRNAexpressionpro?lingrevealsthecrucialroleofhsa-let-7ianditstargetgenesincolorectalcancermetastasis.MolBiolRep?[8]YuW,ZhangY,XuL,SunS,JiangX,ZhangF.Microarray-basedbioinformaticsysisofosteoblastsonTiO2nanotubelayers.ColloidsandsurfacesB,Biointerfaces2012;93:135-42.?[9]YangZY,QuY,ZhangQ,WeiM,LiuCX,ChenXH,etal.Knockdownofmetallopanstimulin-1inhibitsNF-kappaBsignalingatdi?erentlevels:theroleofapoptosisinductionofgastriccancercells.InternationaljournalofcancerJournalinternationalducancer2012;130:2761-70.?[10]YangX,ZhouY,PengS,WuL,LinHY,WangS,etal.Di?erentiallyexpressedsmamicroRNAsinprematureovarianfailurepatientsandthepotentialregulatoryfunctionofmir-23aingranulosacellapoptosis.Reproduction?[11]XiongH,DuW,WangJL,WangYC,TangJT,HongJ,etal.ConstitutiveactivationofSTAT3ispredictiveofpoorprognosisinhumangastriccancer.JMolMed(Berl)2012;90:1037-46.?[12]SunY,YuB,ZhangK,ChenX,ChenD.ParadigmofTime-sequenceDevelopmentoftheIntestineofSucklingPigletswithMicroarray.Asian-AustralasianJournalofAnimalSciences2012;25:1481-92.?[13]ShuzhenS,RouM,XiaomeiH,Xiao-HongY,Yong-GangX,HongzhiW,etal.KaryotypeandDNA-MethylationResponsesinMyelodyssticSyndromesfollowingTreatmentwithTraditionalFormulaContainingArsenic.Evidence-basedcomplementaryandalternativemedicine:eCAM2012;2012:969476.?[14]LiJN,ZhaoL,WuJ,WuB,YangH,ZhangHH,etal.Di?erencesingeneexpressionpro?lesandcarcinogenesispathwaysbetweencolonandrectalcancer.JDigDis2012;13:24-32.?[15]LiA,SongT,WangF,LiuD,FanZ,ZhangC,etal.MicroRNAomeandexpressionpro?leofdevelogerminminiaturepigs.PLoSOne?[16]HuoLR,LiangXB,LiB,LiangJT,HeY,JiaYJ,etal.Thecorticalandstriatalgeneexpressionpro?leof100hzelectroacupuncturetreatmentin6-hydroxydopamine-inducedParkinson'sdiseasemodel.Evidence-basedcomplementaryandalternativemedicine:eCAM2012;2012:908439.?[17]HuoLR,LiangJT,ZouJH,WangLY,LiQ,WangXM.Possiblenovelrolesofpoly(rC)-bindingprotein1inSH-SY5Yneurocytes:anysisusingadynamicBayesiannetwork.NeurosciBull2012;28:282-90.?[36]JiaD,WeiL,GuoW,ZhaR,BaoM,ChenZ,etal.Genome-widecopy?[36]JiaD,WeiL,GuoW,ZhaR,BaoM,ChenZ,etal.Genome-widecopynumberysesidenti?ednovel?[19]ChenWC,LinMS,YeYL,GaoHJ,SongZY,ShenXY.microRNAexpressionpatternanditsal tionfollowingcelecoxibinterventioninhumancolorectalcancer.ExpTherMed2012;3:1039-48.?[20]AnF,GongB,WangH,YuD,ZhaoG,LinL,etal.miR-15bandmiR-16regulateTNFmediatedhepatocyteapoptosisviaBCL2inacuteliverfailure.Apoptosis2012;17:702-16.?[21]ZhaoZ,LiuY,HeH,ChenX,ChenJ,LuYC.Candidategenesin?uencingsensitivity ofglioblastomatoSemustine.BrainResBull2011;86:189-?[22]ZhaoX,MoD,LiA,GongW,XiaoS,ZhangY,etal.Comparativeysesbysequencingoftranscriptomesduringskeletalmuscledevelopmentbetweenpigbreedsdi?eringinmusclegrowthrateandfatness.PLoSOne?[23]ZhangM,GaoY,DuX,ZhangD,JiM,WuG.Toll-likereceptor(TLR)2andTLR4de?cienciesexertdi?erentialinvivoe?ectsagainstSchistosomajaponicum.ParasiteImmunol2011;33:199-209.?[24]ZhangJ,YangY,WangY,ZhangJ,WangZ,YinM,etal.Identi?cationofhubgenesrelatedtothephaseofirradiationinjurybymicroarrayandintegratedgenenetworkysis.PLoSOne?[25]ZhangB,LiuXX,HeJR,ZhouCX,GuoM,HeM,etal.PathologicallydecreasedmiR-26aantagonizesapoptosisandfacilitatescarcinogenesisbytargetingMTDHandEZH2inbreastcancer.Carcinogenesis2011;32:2-9.?[26]YuB,ZhouS,WangY,DingG,DingF,GuX.Pro?leofmicroRNAsfollowingratsciaticnerveinjurybysequencing:implicationformechanismsofnerveregeneration.PLoSOne?[27]YangF,ZhangL,HuoXS,YuanJH,XuD,YuanSX,etal.LongnoncodingRNAhighexpressioninhepatocellularcarcinomafacilitatestumorgrowththroughenhancerofzestehomolog2inhumans.Hepatology2011;54:1679-?[28]WenQ,HuY,ZhangX,KongP,ChenX.Geneexpressionsignatureoflymphocyteinacutelymphoblasticleukemiapatientsimmediayaftertotalbodyirradiation.LeukRes2011;35:1044-51.?[29]WangL,SongH,GongZ,DuanQ,LiangA.AcutepulmonaryembolismanddysfunctionofCD3+CD8+Tcellimmunity.AmJRespirCritCareMed2011;184:1315.?[30]WangL,GongZ,JiangJ,XuW,DuanQ,LiuJ,etal.Confusionofwidethrombolytictimewindowforacutepulmonaryembolism:massspectrographicysisforthrombusproteins.AmJRespirCritCareMed?[31]WangH,HuangM,ZhangDY,ZhangF.Globalpro?lingofsignalingnetworks:studyofbreastcancerstem?[32]WangF,HuS,LiuW,QiaoZ,GaoY,BuZ.Deep-sequencingysisofthemousetranscriptomeresponseinfectionwithBrucellamelitensisstrainsofdi?eringvirulence.PLoSOne?[33]MaoYY,yangH,WangM,PengW,HeQ,ShouZF,etal.Feasibilityofdiagnosingrenalallograftdysfunctionbyoligonucleotidearray:Geneexpressionpro?lecorrelateswithhistopathology.TransplImmunol2011;24:172-?[34]LiuXX,LiXJ,ZhangB,LiangYJ,ZhouCX,CaoDX,etal.MicroRNA-26bisunderexpressedinhumanbreastcancerandinducescellapoptosisbytargetingSLC7A11.FEBSLett2011;585:1363-7.?[35]LiJL,ZhaoL,CuiB,DengLF,NingG,LiuJM.Multiplesignalingpathwaysinvolvedinstimulationofdi?erentiationbyN-methyl-D-aspartatereceptorsactivationinvitro.ActaPharmacolSin2011;32:895-?[37]ChenC,WuCQ,ZhangZQ,YaoDK,ZhuL.LossofexpressionofmiR-335isimplicatedinhepaticslatecellmigrationandactivation.ExpCellRes2011;317:1714-25.?[38]ZhaoW,WangL,ChenP,ZhaoJ,QiY,ChiS,etal.7-aapeptidemimicfromHVR1ofHCVprotectshepaticinjuryinratsbyreducedexpressionofkeypro-in? toryfactors.In? tion&allergydrugtargets?[39]YangK,WangXQ,HeYS,LuL,ChenQJ,LiuJ,etal.Advancedglycationendproductsinducechemokine/cytokineproductionviaactivationofp38pathwayandinhibitproliferationandmigrationofbonemarrowmesenchymalstemcells.CardiovascDiabetol2010;9:66.?[40]XiaoS,WangQ,JiaJ,CongP,MoD,YuX,etal.Proteomechangesoflungsarti?ciallyinfectedwithH-PRRSVandN-PRRSVbytwo-dimensional?uorescencedi?erencegelelectrophoresis.VirolJ2010;7:107.?[41]XiaoS,MoD,WangQ,JiaJ,QinL,YuX,etal.Aberranthostimmuneresponseinducedbyhighlyvirulentidenti?edbydigitalgeneexpressiontagpro?ling.BMCGenomics?[42]XiaoS,JiaJ,MoD,WangQ,QinL,HeZ,etal.UnderstandingPRRSVinfectioninporcinelungbasedonwidetranscriptomeresponseidenti?edbydeepsequencing.PLoSOne?[44]WangL,GongZ,LiangA,XieY,LiuSL,YuZ,etal.CompromisedT-cellimmunityand -likestructureinapatientwithpulmonaryhypertension.AmJRespirCritCareMed2010;182:434-5.?[45]ShenE,DiaoX,WeiC,WuZ,ZhangL,HuB.MicroRNAstargetgeneandsignalingpathwaybybioinformaticsysisinthecardiachypertrophy.BiochemBiophysResCommun2010;397:380-5.?[46]HuS,YaoG,GuanX,NiZ,MaW,WilsonEM,etal.Researchresource:Genome-widemap ofinvivoandrogenreceptorbindingsitesinmouse.MolEndocrinol2010;24:2392-405.?[47]DingJ,HuangS,WuS,ZhaoY,LiangL,YanM,etal.GainofmiR-151onchromosome8q24.3facilitatestumourcellmigrationandspreadingthroughdownregulatingRhoGDIA.NatCellBiol2010;12:390-9.?[48]ChenH.DeterminingthetranscriptionalregulationpatternofPgTIP1intransgenicArabidopsisthalianabyconstructinggene.AdvancesinBioscienceandBiotechnology2010;01:384-90.?[49]ChenF,ZhuHH,ZhouLF,LiJ,ZhaoLY,WuSS,etal.GenesrelatedtotheveryearlystageofConA-inducedfulminanthepatitis:agene-chip-basedstudyinamousemodel.BMCGenomics2010;11:240.?[50]GuoCJ,PanQ,