MedicalBiochemistry溫州醫(yī)科大學(xué)智慧樹(shù)知到答案2024年第一章測(cè)試

Whichsetofaminoacidscanabsorb280nmUVlight?（）

A:Trp&TyrB:Met&CysC:Cys&HisD:Thr&HisE:Glu&Asp

答案:AWhichofthefollowingaminoacidsisinvolvedintheformationofdisulfidebridge?（）

A:CysteineB:tryptophanC:hydroxyprolineD:tyrosineE:methionine

答案:ATheformationofproteinsecondarystructureismainlydependenton（）

A:hydrophobicpackingB:peptidebondC:hydrogenbondD:disulfidebondE:base-stackinginteraction

答案:CEssentialofproteindenaturationis（）

A:ruptureofhydrogenbondsB:damageofprimarystructureC:ruptureofdisulfidebondD:breakofnon-covalentbondsE:breakofpeptidebonds

答案:DTheaminoacidwhichdoesnotexistinnaturalproteinsis（）

A:methionineB:cysteineC:glycineD:citrullineE:lysine

答案:D

第二章測(cè)試

ThebaseisfoundinmRNAbutnotinDNAis（）

A:GB:TC:CD:UE:A

答案:DIfthecontentofadenineis15%inaDNAdoublehelix,thatofcytosineis（）

A:35%B:55%C:75%D:85%E:15%

答案:AWhichofthefollowingstatementsaboutnucleosomestructureiscorrect?（）

A:ThemajorhistonescomprisingnucleosomesareH1andH4.B:NucleosomesaresphericalstructurescomprisedofRNA,nonhistoneproteinsandhistoneproteins.C:NucleosomespermitefficientpackingofDNAtoaboutoneseventhitsnormalvolume.D:ThehistoneassociatedwiththeDNAinthelinkerregionholdingnucleosomesiscalledH2A.E:Alloftheabove.

答案:CThecodoninmRNAreverselycomplementarypairingwithanti-codonUGCintRNAis（）

A:GCAB:AUGC:GCTD:ACGE:TCG

答案:AThe5′endofmRNAinmosteukaryoteshas（）

A:CapstructureB:polyAtailC:initiationcodonD:SDsequenceE:-CCAsequence

答案:A

第三章測(cè)試

Thespecificityofenzymeisdeterminedby（）

A:prostheticgroupB:coenzymeC:SubstrateD:apoproteinE:metalion

答案:DTheeffectofnon-competitiveinhibitoronenzyme-catalyzedvelocityis（）

A:Kmincreased,VmaxunchangedB:Kmdecreased,VmaxdecreasedC:Kmunchanged,VmaxdecreasedD:Kmdecreased,VmaxincreasedE:Kmdecreased,Vmaxunchanged

答案:CAnalogofsulfonamideis（）

A:dihydrofolicacid(DHFA)B:glutamateC:tetrahydrofolicacid(THFA)D:folicacid(FA)E:paraaminobenzoicacid(PABA)

答案:EThephysiologicalsignificanceofzymogenactivationis（）

A:toprotectenzymeactivityB:toacceleratemetabolismC:toavoidself-damageD:tofacilitategrowthE:toresumeenzymeactivity

答案:CIftheenzymaticvelocityis90%ofVmax,[S]shouldbe（）timesofKm.

A:4.5B:90C:5D:9E:8

答案:D

第四章測(cè)試

WhichoffollowingvitaminscanbeconvertedintoNAD+andNADP+?（）

A:VitB1B:VitB12C:VitB6D:VitPPE:VitB2

答案:DWhichofthefollowingvitamindeficienciescausesnightblindness?（）

A:VitEB:VitDC:VitB1D:VitB2E:VitA

答案:ETheactiveformofvitaminDinthebodyis（）

A:1-(OH)-vitaminD3B:24,25-(OH)2-vitaminD3C:24-(OH)-vitaminD3D:25-(OH)-vitaminD3E:1,25-(OH)2-vitaminD3

答案:EFolatedeficiencycancause（）

A:ricketsB:ScurvyC:sickle-cellanemiaD:beriberiE:megaloblasticanemia

答案:AWhichofthefollowingvitaminscontainsthemetalcobaltatom？（）

A:VitPPB:VitEC:pantothenicacidD:VitB2E:VitB12

答案:E

第五章測(cè)試

Whichcoenzymeinpyruvatedehydrogenasecomplexservesasthefinalhydrogensacceptor?（）

A:lipoateB:FADC:NAD+D:biotinE:TPP

答案:CWhichpathwayofthefollowingisrelatedtonucleicacidssynthesis?（）

A:GluconeogenesisB:GlycolysisC:GlycogenolysisD:CitricacidcycleE:Pentosephosphatepathway

答案:EThedirectdonorofglucosylgroupinglycogenesisis（）.

A:CDPGB:GDPGC:UDPGD:G-6-PE:G-1-P

答案:CMuscleglycogencannotreplenishbloodsugarbecausemusclecellslack（）

A:pyruvatekinaseB:glucose-6-phosphataseC:pyruvatecarboxylaseD:Phosphofructokinase-1E:hexokinase

答案:AWhichofthefollowinghormonescanlowerbloodglucose？（）

A:thyroxineB:insulinC:glucocorticoidD:glucagonE:adrenalin

答案:B

第六章測(cè)試

Whichofthefollowingenzymescatalyzestheratecontrollingstepinfattyacidbiosynthesis?（）

A:acetyl-CoAcarboxylaseB:synthetaseC:deacylaseD:dehydrataseE:enoylACPreductase

答案:AWhichofthefollowingisanintermediateinketonebodysynthesis?（）

A:citrateB:3-hydroxy-3-methylglutaryl-CoAC:biotinD:phosphopantetheineE:cyanocobalamin(VitaminB12)

答案:BIndicatethecorrectsequenceofreactionsemployedforbeta-oxidationofacyl-CoAderivativesfromthelistbelow.（）

A:oxidationcoupledtoFAD,hydration,oxidationcoupledtoNAD,thiolysisB:oxidationcoupledtoNAD,hydration,oxidationcoupledtoNAD,thiolysisC:oxidationcoupledtoNAD,thiolysis,oxidationcoupledtoFAD,hydrationD:oxidationcoupledtoFAD,hydration,oxidationcoupledtoFAD,thiolysisE:oxidationcoupledtoFAD,thiolysisoxidationcoupledtoNAD,hydration

答案:AHMGCoAcanactasaprecursorforallofthefollowingEXCEPT:（）

A:bileacids.B:estrogen.C:adrenalcorticalhormones.D:VitaminE:lecithin.

答案:EFattyacidsfromadiposetissuearetransportedtositesofutilizationintheformof（）

A:triglyceridesboundtoserumalbumin.B:chylomicrons.C:freefattyacidsboundtoserumalbumin.D:highdensitylipoproteins.E:verylowdensitylipoproteins.

答案:C

第七章測(cè)試

Whichofthefollowingcomponentsofthemitochondrialelectrontransportsystemareincapableofcarrying2electrons?（）

A:cytochromeCB:FMNC:NAD+D:UbiquinoneE:FAD

答案:AThemainfunctionoftheglycerolphosphateshuttleisin（）

A:anaerobicglycolysisforregenerationofNAD.B:thebiosynthesisofserineforuseinmitochondrialproteinsynthesis.C:thebiosynthesisoftriacylglycerols.D:theβ-oxidationoffattyacids.E:thetransportofreducingequivalentsintomitochondriafromNADHformedduringglycolysis.

答案:ETheuncouplingofoxidativephosphorylationfoundinthebrownfatmitochondriaofanewborninfantmightbeofphysiologicalimportancebecause（）

A:itallowsATPformationB:itincreasesCO2intheblood.C:itproduceswater.D:itproducedheat.E:itraisestheoxygenlevelintheblood.

答案:DATPsynthasecarryoutsubstratelevelphosphorylations.（）

A:對(duì)B:錯(cuò)

答案:BThemitochondrialelectrontransportsystemresponsibleforreoxidationofNADHandelectrontransfertooxygenislocatedininnermembraneofthemitochondria.（）

A:錯(cuò)B:對(duì)

答案:B

第八章測(cè)試

AllofthefollowingareessentialaminoacidsEXCEPT（）

A:TryptophanB:serineC:threonineD:valineE:lysine

答案:BTheaminoacidthatisinvolvedinalmosteveryaminotransferasereactionis（）

A:GlutamineB:glutamateC:pyruvateD:lysineE:aspartate

答案:BThenitrogensinureaoriginateMOSTDIRECTLY(fewestnumberofsteps)from（）

A:NH3andglutamateB:NH3andglutamineC:freeammoniaD:alanineandglutamateE:carbamoylphosphateandaspartate

答案:EPyridoxalphosphateactsascoenzymeinmost（）

A:transaminationreactions.B:carbondioxideincorporatedreactions.C:kinasereactions.D:noneoftheaboveE:dehydrogenationreactions.

答案:ATheprimaryfunctionoftheureacycleis（）

A:thesynthesisofornithineforspermidinesynthesisB:thesynthesisofaspartateC:theproductionofthecitricacidcycleintermediatefumarateD:toconverttoxicammoniatoureawhichcanbeexcretedE:theturnoverofexcessarginine

答案:D

第九章測(cè)試

Whichofthefollowingisthecommonmaterialforthesynthesisofpyrimidineandpurinenucleotide?（）。

A:GlycineB:GlutamineC:FormicacidD:Fumarate

答案:BWhichofthefollowingsubstancedirectlylinksnucleotidesynthesisandglucosemetabolism?（）。

A:Ribose-5-phosphateB:Glucose-6-phosphateC:Glucose-6-phosphateD:Glucose

答案:AWhichofthefollowingisnotaphysiologicalroleofnucleotide?（）。

A:componentsofthecoenzymesFADandCoAB:componentsofmanyproteinsC:carriersofchemicalenergyD:intermediatesforbiosyntheticprocesses

答案:BTheprincipalnitrogenousurinaryexcretionproductinhumansresultingfromthecatabolismofAMPis（）

A:uricacidB:ureaC:creatinineD:thiamine

答案:AWhichoneofthefollowingdoesnotoccursinthedegradationpathwayofAMP?（）

A:AdenineisconvertedtohypoxanthineB:AdenosineisconvertedtoadenineC:AMPisconvertedtoadenosineD:TheendproductisCO

答案:D

第十章測(cè)試

Allproductsofliverbiotransformationarenontoxic.（）

A:對(duì)B:錯(cuò)

答案:BIntheenterohepaticcirculationonlyalittlefractionofbileacidsarereabsorbedintheintestine.（）

A:對(duì)B:錯(cuò)

答案:BWhichofthefollowingreactionsisthemostcommonconjugationintheliver?（）

A:ConjugationwithacetateB:ConjugationwithsulfateC:ConjugationwithglutathioneD:Conjugationwithglucuronicacid

答案:DWhichofthefollowingreactionsisthemostcommonconjugationintheliver?（）

A:UDPGAB:SAMC:PAPSD:UDPG

答案:CWhichofthefollowingenzymeistherate-limitingenzymeintheprocessofbileacidssynthesis?（）

A:3α-dehydroxylationB:7α-dehydroxylationC:3α-hydroxylationD:7α-hydroxylation

答案:D

第十一章測(cè)試

Thebilirubinissparinglysolubleinplasmaandwater.（）

A:錯(cuò)B:對(duì)

答案:BUnconjugatedbilirubincanbesecretedintotheurineinourbodies.（）

A:對(duì)B:錯(cuò)

答案:BWhatdothedailybilirubinformationderivemainlyfrom?（）

A:myoglobinB:bilinC:hemoglobinD:cytochrome

答案:CWhat‘sthematerialsofhemesynthesis?（）

A:glycine,succinylCoA,Fe2+B:arginine,succinylCoA,Fe2+C:glycine,acetyl-CoA,Cu2+D:glycine,acetyl-CoA,Fe2+

答案:AHowmanyoxygenscanamoleculeofhemoglobinbind?（）

A:3B:1C:4D:2

答案:C

第十二章測(cè)試

ThesequenceofoneDNAstrandisATGCAA,thecomplementarystrandofDNAis（）

A:UUGCAUB:TTGCATC:UAGCAAD:ATGCAAE:TACGTT

答案:BTheenzymeinchargeofproofreadingfunctioninDNAreplicationis（）

A:DNAligaseB:PrimaseC:TopoisomeraseD:DNApolymeraseE:Helicase

答案:DInthereplicationofeukaryoticDNA,（）

A:bothleadingstrandandlaggingstrandaresynthesizedinadirectionoppositetothatinwhichthereplicationforkmoves.B:thetemplateisreadinthe5’3’direction.C:thelaggingstrandissynthesizedinthedirectiontakenbythereplicationfork.D:anewDNAstrandisalwayssynthesizedinthe3’5’direction.E:theleadingstrandissynthesizedinthedirectiontakenbythereplicationfork.

答案:EWhatisthefunctionofthe3'to5'exonucleaseactivityofbacterialDNApolymerases?（）

A:processesprecursorsofribosomalRNAB:removesmismatchedbasesduringreplicationC:removestheRNAprimersofOkazakifragmentsD:initiatesmRNAsynthesis

答案:BAllofthefollowingstatementsconcerningDNAreplicationinprokaryotesaretrueEXCEPT____?（）

A:Replicationisbidirectionalfromasingleinitiationpoint.B:Replicationoccursina5'to3'direction.C:OkazakifragmentsarejoinedbyDNApolymeraseIII.D:UnwindingofthedoublehelixrequiresATPhydrolysis.

答案:CDNApolymeraseIIIcanonlyaddnucleotidestoanexistingchain,so_____isrequired.（）

A:helicaseB:aDNAprimerC:DNApolymeraseID:anRNAprimer

答案:DXerodermapigmentosum(xp)resultsfromadeficiencyin_____.（）

A:atumorsuppressorB:collagensynthesisC:DNArepairD:DNAreplication

答案:CRegardingtheprocessofDNAreplicationinE.coliwhichofthefollowingstatementsisWRONG?（）

A:DNAreplicationisunidirectional.B:Thereisauniquesiteatwhichreplicationisinitiated.C:DNAreplicationisasemiconservativeprocess.D:Themechanismofreplicationissuchthatthereisaleadingstrandandalaggingstrandateachreplicatingfork

答案:ADNApolymeraseIdonothas_____.（）

A:polymeraseactivity.B:HelicaseactivityC:3’→5’exonucleaseactivity.D:5’→3’exonucleaseactivity.

答案:BOkazakifragmentsare_____.（）

A:synthesizedinthe3'to5'direction.B:assembledascontinuousreplication.C:foundonthelaggingstrand.D:foundontheleadingstrand.

答案:C

第十三章測(cè)試

ThetemplatestrandofDNAis5’-ATTCAG-3’,itstranscriptis（）

A:5’-CTGAAT-3’B:5’-GACTTA-3’C:5’-UAAGUC-3’D:5’-CUGAAU-3’E:5’-TAAGTC-3’

答案:DWhichofthefollowingisNOTtrueoftheprokaryotic(E.coli)transcriptionalprocess?（）

A:specificsequencesinthepromoterarenecessaryforstablebindingofRNApolymerase.B:terminationrequiresspecialsequences(signals)inthenascentRNAchain.C:sigmafactorisrequiredonlyduringtheinitiationprocess.D:AseparatehelicaseenzymeisnecessaryforunwindingtheDNAtemplatetocreateanopencomplex.

答案:DTheTATAboxineukaryotesisa_____.（）

A:5'cap.B:corepromoter.C:-35sequence.D:-10sequence.

答案:BWhichofthefollowingstatementsiscorrectaboutprokaryoticgeneexpression?（）

A:ProkaryoticmRNAsareoftentranslatedbeforetranscriptioniscomplete.B:ProkaryoticmRNAsmusthaveintronssplicedout.C:Allofthesestatementsarecorrect.D:ProkaryoticmRNAscontainthetranscriptofonlyonegene.

答案:AIndicatewhichofthefollowingeventscanoccurduringtheprocessingofeukaryoticmRNAtranscripts.（）

A:Excisionsofintrons.B:Attachmentofapoly(A)tailtothe5’endofthetranscript.C:Splicingtogetherofexons.D:MethylationofallGresidues.

答案:ATheAAUAAAsequenceonaRNAmoleculemarks_____.（）

A:Thesitewherethereleasefactorwillbindtoendpolypeptidesynthesis.B:Thesitenearwhichtheprimarytranscriptiscleavedandapoly(A)sequenceisadded.C:Thesitewhereribosomesbindtoinitiatepolypeptidesynthesis.D:Thesitewheretranscriptionstops.

答案:BRNApolymeraseisboundinitiallyto_____ofanoperon?（）

A:OperatorB:structuralgenesC:enhancerD:Promoter

答案:DPost-translationalmodificationsofpolypeptidesincludeallthefollowingEXCEPT_____?（）

A:disulfidebondformationB:cappingby7-methylguanidineC:proteasecleavageD:removalofmethionine

答案:B

第十四章測(cè)試

Thedirectionofproteinsynthesis(polypeptidechain)is（）

A:From5’to3’B:FromNtoCC:From3’to5’D:NoneofaboveE:FromCtoN

答案:BThesequenceofnucleotideofinitiationcodenis（）

A:AUGB:UA