1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEChlorogenic acidCat. No.: HY-N0055CAS No.: 327-97-9Synonyms: 3-O-Caffeoylquinic acid; Heriguard; NSC-407296分式: CHO分量: 354.31作靶點: HIF/HIF Prolyl-Hydroxylase; Reactive Oxygen Species作通路: Metabolic Enzyme/Protease; Immunology/Infla

2、mmation; NF-B儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數據體外實驗 DMSO : 32 mg/mL (90.32 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.8224 mL 14.1119 mL 28.2239 mL5 mM 0.5645 mL 2.8224 mL 5.6448 mL10 mM 0.2822 mL 1.4112 mL

3、 2.8224 mL請根據產品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Chlorogenic acid咖啡和茶中的主 酚類化合物。 它具有些重 的治療作，如抗氧化活性，抗菌，保肝，臟保護，抗炎，解熱，神經保護，抗肥胖，抗病毒，抗微物，抗壓。戶使本產品發(fā)表的科研獻1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE Food Chem. 2017 Aug 1;228:143-151. Int J Biol Macromol. 2019 Jun 19. pii: S01

4、41-8130(19)31998-1.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Park JJ, et al. Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1/AKT pathway. Cell Oncol(Dordr). 2015 Jan 6.2. Park SH, et al. IRAK4 as a Molecular Target in the Ameliorati

5、on of Innate Immunity-Related Endotoxic Shock and Acute Liver Injury byChlorogenic Acid. J Immunol. 2015 Feb 1;194(3):1122-30.3. Kang JW, et al. Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats. Biomol Ther (Seoul). 2014Sep;22(5):420-5.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-