早期胃癌病理及NBI放大的一些知識點-0501黏膜肌層（內(nèi)環(huán)外縱固有肌層（內(nèi)斜）

MIB1-positiveproliferatingcellsarelocatedintheneckregionofthefundicglandmucosa （胃底腺

約占小凹及腺體厚度

小腸型吸收細(xì)胞（有刷狀緣）、杯狀細(xì)胞（涎酸 ） 柱 細(xì)胞（分泌中 ）、杯狀細(xì)胞（分泌涎酸 大腸型吸收細(xì)胞（無刷狀緣）、杯狀細(xì)胞（涎酸 柱 細(xì)胞（分泌硫酸 ）、杯狀細(xì)胞（分泌涎酸 及硫酸 LBC(LightblueTheLBCisdefinedas“afine,blue,whitelineonthecrestsoftheepithelialsurface” adenocarcinoma(tub1) adenocarcinoma(tub2)Papillaryadenocarcinomasolidtype(por1)non-solidtype(por2)Signet-ringcellcarcinomaMucinousadenocarcinoma

MUC5AC-and/orMUC6-positiverateof10%orMUC2-and/orCD10-positiverateof10%orMUC5AC-and/orMUC6-aswellasMUC2-and/orpositiveratesof10%orAllpositiverateslowerthan intraepithelial 再生性或反應(yīng)性丌典型增生（非上皮內(nèi)瘤變 LowHighHigh假復(fù)層明顯，游離緣可見明顯核像，胞漿幾乎丌含；腺體可見復(fù)雜分支結(jié)構(gòu)，可見腺體內(nèi)折，腺箭頭處可見病理性核

Low expressMUC5AC,butdonotexpress Highpleomorphicnucleithatlackbasal positiveMUC6immunohistochemicalpyloricglandfrequentlyexpressMUC6andtubulovillous tubularDiagnosticCriteriaforGastricMucosal GastricGastricHigh-grade siaCanBeAssociatedWithSubmucosalAmJSurgPatholVolume38,Number11,November分 （腸化背景tortuousanastomosing

branchingdistendedy

inverywell-ofintestinaltype. 祛除

隱窩開口

中間區(qū)域GastricSulci:胃小溝（劃分胃小區(qū)）結(jié)構(gòu)，隱窩開口（其實隱窩開口未上皮下微血管中間區(qū)域隱窩開口 WOS(whiteopaqueoilredOoilredOoilredO 單個隱窩上皮表現(xiàn)為丌規(guī)則的管狀、線形、弧形、狀、絨Demarcation welldifferentiated-typeadenocarcinomalocatedinthelaminapropriaofthewelldifferentiated-typeadenocarcinomalocatedinthelaminapropriaoftheUndifferentiat