口服降糖藥物,,,,,,,,,

傳統(tǒng)的五類口服降糖藥物,籠統(tǒng)分類,藥物類別,通用名,原研藥商品名,國產(chǎn)仿制藥商品名（名字不全）,劑型規(guī)格（每片）,每次常用劑量,用藥次數(shù),備注

,促進(jìn)胰島素分泌的藥物（促泌劑）,磺脲類,格列齊特片,達(dá)美康,,80mg,80mg,bid,

,,,格列齊特緩釋片,達(dá)美康緩釋片,仁和,"30mg,60mg",30-120mg,qd,

,,,格列吡嗪片,美吡達(dá),迪沙，丹泰，元坦,"2.5mg,5mg",2.5-5mg,tid,

,,,格列吡嗪控釋片,瑞易寧,秦蘇，康恩貝,5mg,5mg,qd,

,,,格列美脲片,亞莫利,萬蘇平,"1mg,2mg",2mg,qd,

,,,格列本脲片,優(yōu)降糖,消渴丸（計(jì)入此類）,2.5mg,1.25-2.5mg,bid-tid,

,,,格列喹酮片,,糖適平,30mg,30mg,tid,

,,格列奈類,瑞格列奈片,諾和龍,,"0.5mg,1mg,2mg",0.5-2mg,tid,

,,,那格列奈片,唐力,,"60mg,120mg",60-120mg,tid,

,增加胰島素敏感性的藥物,雙胍類,二甲雙胍片,格華止,太多了，不勝枚舉,"0.25,0.5,0.85","0.25,0.5,0.85",bid-tid,

,,噻唑烷二酮類（TZD類）,羅格列酮片,文迪雅,太羅，,4mg,4mg-8mg,qd,

,,,吡格列酮片,艾可拓,卡司平,"15mg,30mg","15mg,30mg",qd,

,降糖作用不通過胰島素,糖苷酶抑制劑,阿卡波糖片,拜唐蘋,卡博平,50mg,50-100mg,tid,

,,,伏格列波糖片,倍欣,,"0.2mg,0.3mg",0.2mg,tid,

,,,米格列醇片,,,"25mg,50mg,100mg","25mg,50mg,100mg",tid,

近幾年新的降糖藥物,,,,,,,,,

,,藥物類別,通用名,原研藥商品名,劑型規(guī)格,每次常用劑量,用藥頻率,備注,

二肽基肽酶4抑制劑(DPP-IVinhibitor),也屬于促進(jìn)胰島素分泌的藥物，但不容易引起低血糖,DPP-4五朵金花（方便記憶哈）,西格列汀,捷諾維,100mg,100mg,qd,,新藥尚在專利保護(hù)期，暫無國內(nèi)仿制藥

,,,維格列汀,佳維樂,50mg,50mg,bid,,

,,,阿格列汀,尼欣那,"6.5mg,12.5mg,25mg",25mg,qd,,

,,,利格列汀,歐唐寧,"2.5mg,5mg",5mg,qd,,

,,,沙格列汀,安立澤,5mg,5mg,qd,,

GLP-1類似物（受體激動(dòng)劑）,,GLP-1類,利拉魯肽,諾和力,18mg,0.6-1.2mg,qd,均為皮下注射,

,,,艾塞那肽,百泌達(dá),"5ug,10ug","5ug,10ug",bid,,

,,,長(zhǎng)效艾塞那肽,百達(dá)楊,2mg,2mg,qw,剛上市,

,,,索瑪魯肽,,,,,美國去年上市,

2型鈉葡萄糖共轉(zhuǎn)運(yùn)子抑制劑(SGLT-2),降糖作用不通過胰島素,SGLT-2類藥物,達(dá)格列凈,安達(dá)唐,10mg,,,,

,,,恩格列凈,歐堂靜,,,,,

固定復(fù)方制劑,卡雙平,TZD/metformin,吡格列酮/二甲雙胍,,15mg/0.5,,bid,,

,捷諾達(dá),DPP-4/metformin,西格列汀/二甲雙胍,,50mg/0.85或50mg/0.5,,bid,,

,宜合瑞,DPP-4/metformin,維格列汀/二甲雙胍,,50mg/0.85,,bid,,

,待補(bǔ)充,,,,,,,,

胰島素類,,,,,,,,,

,類別,通用名,商品名,進(jìn)口或國產(chǎn),每次常用劑量,常用次數(shù),備注,,

模擬餐時(shí)分泌(prandialinsulin),短效胰島素（人胰島素）,重組人胰島素,諾和靈R,丹麥,4-12u,qd-tid,,,

,,重組人胰島素,優(yōu)泌林R,美國,4-12u,qd-tid,,,

,,重組人胰島素,重合林R,德國,4-12u,qd-tid,,,

,,重組人胰島素,甘舒霖R,國產(chǎn),4-12u,qd-tid,,,

,,重組人胰島素,優(yōu)思林R,國產(chǎn),4-12u,qd-tid,,,

,,重組人胰島素,萬邦林R,國產(chǎn),4-12u,qd-tid,,,

,速效胰島素（即人胰島素類似物),門冬胰島素,諾和銳,丹麥,4-12u,qd-tid,,,

,,賴脯胰島素,優(yōu)泌樂,美國,4-12u,qd-tid,,,

,,谷賴胰島素,艾倍得,法國,4-12u,qd-tid,,,

模擬基礎(chǔ)分泌(basalinsulin),中效胰島素（魚精蛋白鋅胰島素）,,,,,,,,

,,NPH,以上諾和靈R等各種R均對(duì)應(yīng)N,,4-12u,qd或者bid,,,

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,長(zhǎng)效胰島素（胰島素類似物）,甘精胰島素,來得時(shí)（法國）,長(zhǎng)秀霖（國產(chǎn)）,,qd,,,

,,地特胰島素,諾和平（丹麥）,,8-36,qd或者bid,,,

,,德谷胰島素,諾和達(dá)（丹麥）,,,qd,,,

同時(shí)模擬基礎(chǔ)-餐時(shí)分泌（biphasicinsulin),預(yù)混胰島素,,,,,,,,

,,低預(yù)混,諾和靈30R,"重組人胰島素占30%,NPH占70%",,,,,

,,,優(yōu)泌林70/30,,,,,,

,,,甘舒霖30R,,,,,,

,,中預(yù)混,諾和靈50R,重組人胰島素和NPH各占50%,,,,,

,,,優(yōu)思林50R,,,,,,

,預(yù)混胰島素類似物,,,,,,,,

,,低預(yù)混,諾和銳30,門冬胰島素占30%，與魚精蛋白結(jié)合的門冬胰島素（中效）占70%,,,,,

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