Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemE3-Amino-5-hydroxybenzoicacid-13CCat.No.:HY-178299SCASNo.:773801-41-5分子式:C???CH?NO?分子量:154.13作用靶點(diǎn):Isotope-LabeledCompounds;DrugIntermediate作用通路:Others儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性3-Amino-5-hydroxybenzoicacid-13C是13C標(biāo)記的3-Amino-5-hydroxybenzoicacid(HY-W077634)。3-Amino-5-hydroxybenzoicacid(AHBA)是安霉素類(lèi)抗生素mC7N單元的生物合成前體，包括安霉素a和格爾達(dá)霉素，以及抗腫瘤抗生素絲裂霉素C。3-Amino-5-hydroxybenzoicacid可能是由葡萄糖經(jīng)莽草酸途徑的早期中間體。體外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattentionbecauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.REFERENCESMaoY,etal.MolecularcharacterizationandanalysisofthebiosyntheticgeneclusterfortheantitumorantibioticmitomycinCfromStreptomyceslavendulaeNRRL2564.ChemBiol.1999Apr;6(4):251-63.FlossHG,etal.Thebiosynthesisof3-amino-5-hydroxybenzoicacid(AHBA),theprecursorofmC7Nunitsinansamycinandmitomycinantibiotics:areview.JAntibiot(Tokyo).2011Jan;64(1):35-44.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:021-