第1題Drugis（）AAchemicalsubstanceBChemicalsubstancesthatcaninterferewithcellmetabolismCChemicalsubstancesusedtoprevent,treat,anddiagnosediseasesDSubstancesthatcanaffectthebody'sphysiologicalfunctionsESubstanceswithnourishing,healthcare,andhealingeffects第2題Pharmacologyistostudy（）APharmacokineticsBPharmacodynamicsCDrugsDPhysiologyrelatedtodrugsETheinteractionbetweendrugsandthebody,anditslaws正確答案：E第3題Theresearchobjectofpharmacologyis()AhumanbodyBbodyCAnimalpathologymodelDHealthysubjectsEHealthyanimals第1題Weakacidsareexcretedfasterin____urineandweakbasesareexcretedfasterin____urine.AAcidic;AlkalineBAlkaline;AcidicCAcidic;NeutralDNeutral;Alkaline第2題Forintravenous(IV)dosages,whatisthebioavailabilityassumedtobe?A0.25B0.5C0.75D1Testforchapter3第1題Thepharmacologicalbasisofadversedrugreactionsis()AOverdosingBLowselectivityofpharmacologicaleffectsCThepatientsufferedfromliverandkidneydysfunctionDTheplasmaconcentrationistoohighESpecialheterogeneousreaction第2題Theroleofatropineinthetreatmentofbiliarycolic,causingblurredvision,iscalled()AToxiceffectsBSideeffectsCTherapeuticeffectDAllergicreactionEStressreactionTestforchapter4第1題WhichofthefollowingisclassifiedasbelongtotheGproteincouplingreceptors?AGABAreceptorBβadrenergicreceptorCinsulinreceptorDnicotinicIIreceptor第2題Whichdirectionwouldanoncompetitiveantagonist(plusagonist)shiftthedoseresponsecurvewhencomparedtoafullagonist?AUpBTotheleftCTotherightDTotherightanddownTestforchapter1第1題Whichofthefollowingagonistswouldbeusedforcardiacarrest,heartblock,orheartfailure?Aα1-agonistBα2-agonistCβ1-agonistDβ3-agonist第2題WhichofthefollowingisNOTanindicationforβ-blockertherapy?AHypotensionBAnginapectorisCArrhythmiasDMyocardialinfarctionTestforchapter2第1題Whatispilocarpinemostcommonlyusedfor?AFordecreasingheartrateBTodecreasebloodpressure(vasodilation)CForurinaryretentionDDecreasingintraocularpressure第2題Whatistheactionmechanismofpilocarpine?AActivatingM,NreceptorsBBlockingM,NreceptorsSelectivelyCSelectivelyactivatingMreceptorDSelectivelyactivatingNreceptorTestforchapter3第1題Whichofthefollowingdrugswouldbeusedtotreatmyastheniagravis?AAtropineBNeostigmineCAcetylcholineDScopolamine第2題ThecontraindicationofneostigmineisAGlaucomaBParoxysmalsupraventriculartachycardiaCMyastheniagravisDMechanicalintestinalobstructionTestforchapter4第1題Themechanismoforganophosphatepoisoningis()AExcitingtheMreceptordirectlyBExcitingtheNreceptordirectlyCInhibitionofphosphodiesteraseDInhibitionofcholinesteraseEInhibitionofmonoamineoxidase第2題Thesymptomsoforganophosphatepoisoningthatdonotbelongtom-likesymptomsare()ACorestenomaBTears,salivationCAbdominalpainanddiarrheaDAmyostasiaEUrinaryincontinence第3題Diophosphoridineiodidesavesorganophosphatepoisoningbecause()AResurrectingcholinesteraseBresistingacetylcholineCBlockingtheMcholinereceptorDBlockingtheNcholinereceptorEResistingthetoxicityoforganophosphateestersTestforchapter5第1題Thepharmacologicalactionofpropranololinthetreatmentofarrhythmiaisbasedon()ABlockingβreceptorBMembranestabilizingactivityCNointrinsicsympathomimeticactivityDBlockingSodiumchannelENoneofthatistrue第2題Propranololdoesnothaveoneofthefollowingeffects?AInhibitionofreninsecretionBIncreasingglycogenbreakdownCInhibitinglipolysisDReducingtheoxygenconsumptionoftheheartEIncreaseingrespiratoryresistance第3題Whichdrug,givenintravenouslyafterintravenouspropranolol,showstheeffectofraisingbloodpressure?AEpinephrineBIsoprenalineCChlorpromazineDScopolamineENeostigmineTestforchapter6第1題Whichofthefollowingisanadverseaffectofatropine?AIncreasedsalivationBBlurredvisionCBradycardiaDDiaphoresis第2題Whattypeofdrugsareatropine,scopolamine,andpirenzepine?AAcetylcholineagonistsBMuscarinicagonistsCMuscarinicantagonistsDAcetylcholinesteraseinhibitorsTestforchapter7第1題whatdrugshouldbeusedtotreatuppergastrointestinalbleeding（）ANorepinephrineBDopamineCEphedrineDAdrenalineEClonidine第2題Whichofthefollowingisthemaineliminationrouteofnorepinephrineafterthereleasefromnerveendings（）AMetabolizedandinactivatedbyCOMTBMAOmetabolicinactivationCPresynapticmembranereuptakeDReuptakebytheliverEReuptakebyvascularsmoothmuscle第3題Regardingthenarrativeofnorepinephrine,whatiswrong（）APositiveinotropiceffectBWeaklyagonizeβlreceptorsCExcitatoryαreceptorDExcitingβ2receptorECanbeinactivatedbyMAOandCOMTTestforchapter8第1題Themainpurposeofthecompatibilityoftraceepinephrinewithlocalanestheticsis（）APreventanaphylacticshockBPreventhypotensionCLocalvasoconstrictionpromoteshemostasisDProlongtheactiontimeoflocalanestheticsandpreventabsorptionpoisoningEStrengthenanesthesia第2題Whichofthefollowingoptionsisnotacontraindicationtoadrenaline（）AhypertensionBdiabetesCHyperthyroidismDCardiogenicasthmaEBronchialAsthma正確答案：E第3題Treatmentofanaphylacticshockcausedbypenicillin，whichshouldbethefirstchoice（）AAdrenalineBNoadrenalineCEphedrineDDopamineEIsoproterenalineTestforchapter9第1題Whichcanbeusedtoeliminatenasalcongestioncausedbynasalmucosalcongestion（）ANoradrenalineBAdrenalineCIsoprenalineDEphedrineEDopamine第2題Comparedwithepinephrine,ephedrineischaracterizedby（）AStrongeffect,butnotlong-lasting,withexcitatorycentraleffectBTheboostingeffectisweak,long-lasting,easytocausetolerance,andhasacentralexcitatoryeffectCTheeffectisweak,themaintenancetimeisshort,andithastheeffectofrelaxingsmoothmuscleDOraladministrationcanavoidtolerabilityandcentralstimulusENovasodilatoreffect,longmaintenancetime,intolerableTestforchapter10第1題Severeatrioventricularblockshoulduse（）ANorepinephrineBAtropineCIsoprenalineDAdrenalineEAminophylline第2題Thepharmacologicaleffectsofisoproterenolare（）AExcittheheart,raisesystolicanddiastolicbloodpressure,relaxbronchialsmoothmuscleBExcittheheart,raisesystolicbloodpressure,lowerdiastolicbloodpressure,relaxbronchialsmoothmusclesCExcittheheart,lowersystolicanddiastolicbloodpressure,relaxbronchialsmoothmuscleDExcittheheart,raisesystolicanddiastolicbloodpressure,andcontractbronchialsmoothmuscleEInhibittheheart,reducesystolicanddiastolicbloodpressure,relaxbronchialsmoothmuscle第3題Whateffectdoesisoproterenolhavenotbutepinephrinedoes?（）ARelaxbronchialsmoothmuscleBExcitingβ2receptorCInhibitthereleaseofallergicmediatorssuchashistamineDPromotetheproductionofcAMPEContractionofbronchialmucosalbloodvessels正確答案：ETestforchapter11第1題PhentolaminecanmostlikelybeusedtotreatAPeripheralarterialspasmBAnginapectorisCArrhythmia

DHypertension第2題Whichofthefollowingdrugscanbeusedtotreatlowbloodpressureinducedbyphentolamine?AEpinephrineBNorepinephrineCAcetylcholineDNeostigmineTestforchapter1第1題ThedoseofantianxietyeffectofdiazepamisALowdoseoraladministrationBMediumdoseoraladministrationCHighdoseoraladministrationDintravenousinjection第2題ThefirstchoiceoftreatmentofepilepticstatusisAPhenobarbitalBDiazepamCEthosuximideDPhenytoinsodiumTestforchapter2第1題以下哪個(gè)是治療失神性癲癇首選藥物?A苯妥英鈉B卡馬西平C乙琥胺D靜脈滴注地西泮第2題以下哪個(gè)是治療癲癇持續(xù)狀態(tài)首選藥物?A丙戊酸B卡馬西平C乙琥胺D靜脈滴注地西泮Testforchapter3第1題WhichisNOTtrueforL-DOPAinPDtreatment?

AItcancrossthebloodbrainbarrieranddopaminecannot

BSmalldosesofL-DOPAarerequiredCL-DOPAisrapidlymetabolizedtodopaminebyDOPAdecarboxylaseDItismetabolicprecursorofdopamine第2題Thereasonforco-administrationofCarbidopatoL-DOPAis

ACarbidopaisadopamineagonistBCarbidopaisadopamineantagonistCCarbidopainhibitsDOPAdecarboxylationinthecentralDCarbidopainhibitsDOPAdecarboxylationintheperipheralTestforchapter4第1題WhatmedicineshouldbeusedtorescuechlorpromazineacutepoisoningAAdrenalineBNorepinephrineCEphedrineDIsoproterenol第2題Parkinson'ssyndromecausedbychlorpromazineisduetoAblockingMreceptorBblockingαreceptorCblockingD2receptorsinthemesencephalic-limbiclobeandmesencephalic-corticalpathwaysDblockingD2receptorinthenigra-striatumpathway第3題Drymouth,constipationandblurredvisioncausedbychlorpromazinecausesisduetoblockingMreceptorTestforchapter5第1題WhichisNOTthedrugactionofMorphine?ADehydrationBMiosisCAnalgesiaDEuphoria第2題WhichisNOTthesideeffectofMorphine?

ANauseaandvomitingBCoughCRespiratorydepressionDUrinaryretentionTestforchapter6第1題ThemainanalgesicsiteofantipyreticanalgesicsisAgliallayerofspinalcordBmedialthalamusCbrainstemDperiphery第2題ThecharacteristicsofaspirinareAItcaninactivatecyclooxygenaseandreduceTXA2productionBIthaseffectsofanti-inflammationandanti-rheumatismCItcaninhibituricacidproductionandpreventgoutDItcanlowerthebodytemperatureofnormalandfebrilepatients.正確答案：ABTestforchapter1第1題ThemostcommonadverseeffectofACEIis：ADrycoughBHeadacheCRespiratorysuppressionDHyperpotassium第2題WhichofthefollowingistrueaboutCaptopril?ADecreasesserumangiotensinIconcentrationBIncreasesserumangiotensinIIconcentrationCIncreasesserumsodiumconcentrationDIncreasesserumpotassiumconcentration第3題Ramiprilisclassifiedas:AAngiotensinconvertingenzymeinhibitor(ACEI)BAngiotensinreceptorblocker(ARB)CCalciumchannelblocker(CCB)DDiureticsTestforchapter2第1題WhatkindofmedicineisdiltiazemASodiumchannelblockersBCalciumchannelblockersCH1receptorblockerDH2receptorblocker第2題TheEnglishabbreviationofcalciumchannelblockerorcalciumantagonistisAACEIBCCBCARBDβ-RBTestforchapter3第1題Whatcancausea"cinchona"reactionisAAmiodaroneBPhenytoinsodiumCPropranololDQuinidine第2題ThebesttreatmentfortachyarrhythmiacausedbycardiacglycosidepoisoningAVerapamilBAmiodaroneCQuinidineDPhenytoinsodiumTestforchapter4第1題WhichdrugexertsadiureticeffectbycompetingforaldosteronereceptorsATriamtereneBSpironolactoneCAcetazolamideDBumetanide第2題ThefollowingdrugscaneasilycausehyperuricemiaASpironolactoneBTriamtereneCMannitolDHydrochlorothiazideTestforchapter5第1題Captoprilbelongstowhichclassofantihypertensivedrugs?Acentrally-actingsympatholyticBbeta-adrenoceptorantagonistCangiotensinIIconvertingenzymeinhibitorDangiotensinIIreceptorantagonist第2題Vascularsmoothmusclerelaxationbymeansofcalciumchannelblockade:Ahydralazine(Apresoline)Bnitroprussidesodium(Nipride)Cnifedipine(Procardia,Adalat)Dcaptopril(Capoten)Testforchapter6第1題Associatedwithcongestiveheartfailure,particularlywithadvanceddisease:AIncreasesintheventricularpreloadBIncreasesinpulmonarycapillarypressureCDyspneaDAlltheabove第2題Mostcommonsymptomofheartfailure:APeripheraledemaBDyspneaCPulmonaryhypertensionDAngina第3題ConcerningtheuseofACEinhibitorsinheartdisease:ABenefitsduetoreductionincirculatingangiotensinIIlevelsBContraindicatedindiabeticpatientsCContraindicatedinhypertensivepatientswithhypertrophicleftventriclesDReducesefficacyofdiuretictreatmentrequiringhigherdiureticdosagesTestforchapter7第1題Calciumchannelblockerwithmarkednegativeinotropiccardiaceffects:ADiltiazem(Cardiazem)BNifedipine(Procardia,Adalat)CAmlodipine(Norvasc)DAmrinone(Inocor)第2題Digoxin(Lanoxin,Lanoxicaps)clinicaluses:AAtrialfibrillationBAtrialflutterCCongestiveheartfailureDA,B&CTestforchapter8第1題WhichareNOTthedeterminantsofcardialoxygenrequirement?AAtrialwalltensionBHeartrateCVentricularcontractilityDPreloadofheartEAfterloadofheart第2題WhichkindofdrugscanNOTtreatanginapectoris?ACalciumchannelblockersBBetaadrenoceptorblockersCNitroglycerinDSodiumnitroprussideEAnti-platelet

drugs第3題WhichisNOTthecharacteristicofnitroglycerin?AGettingclinicaleffectsquicklyBOraladministrationconvenientlyCDilatingischemiacoronaryarteryselectivelyDDilatingarteryandveinstronglyEDecreasingpreloadandafterloadofheartTestforchapter8第1題ThefirstchoicefortreatmentofhypercholesterolemiaAProbucoBLovastatinCGemfibeziDniacin第2題The

drugs

of

broad-spectrum

blood

lipid

regulation

areAcoleenamineBChondroitin

sulfateCC.

Docosahexaenoic

acidDniacintestforchapter1第1題華法林引起的出血應(yīng)用什么治療：A去甲腎上腺素B維生素KC氨基甲苯酸D對(duì)氯苯甲酸第2題肝素的抗凝機(jī)制是：A維生素K拮抗劑B抑制血小板功能C激活和增強(qiáng)抗凝血酶ⅢD激活纖溶酶原Testforchapter2第1題Whichofthefollowingdrugsdoesnotinhibitplateletfunction:AAspirinBUrokinaseCRidogrelDDipyridamole第2題Whichistrueabouttheanti-plateletmechanismofasprin:AInhibitingCOX-1andeventualreducingTXA2synthesisinplateletsBBlockingplateletmembraneglycoproteinIIb/IIIareceptorCIncreasingcAMPinplateletsDInhibitingADPactivatingplatelet第3題Whichistrueabouttheanti-plateletroleofaspirin:ALowdoseaspirininhibitsplateletaggregationBHigh-doseaspirininhibitsplateletaggregationCLow-doseaspirinmainlyinhibitsvascularendothelialCOX-1andreducesPGI2synthesisDLow-doseaspirinmainlyinhibitsCOX-1inplateletsandreducesTXA2synthesis正確答案：ADTestforchapter3第1題Whichofthefollowingdrugsdoesomeprazolebelongto?AH2receptorblockersBMreceptorblockersCH+-K+-ATPaseinhibitorsDH1receptorblockers第2題Thepueposeofcombiningaluminumhydroxidewithmagnesiumtrisilicateis:AProlongingtheactiontimeBPreventionofgasproductionCReducinggastrointestinalreactionsDReducingdrugabsorptionTestforchapter4第1題Themechanismofadrenocorticalhormoneinthetreatmentofasthmais:AExcitementβ2receptorBBlockingadenosinereceptorCBlockingMreceptorDAnti-inflammatoryandanti-allergiceffects第2題Whichdrugisusedforpreventionofallergicasthma:AIsoproterenolBEphedrineCSodiumcromoglycateDAdrenalineTestforchapter5第1題Theeffectofglucocorticoidsonbloodcomponentsiscorrectlydescribed:AReducesthenumberofneutrophilsBReducesredbloodcellcountCReducesthenumberoflymphocytesDReducesplateletcount第2題Whichistheglucocorticoidthatworkonlyaftertransformationinliver:AHydrocortisoneBPrednisonCDexamethasoneDTriamcinolone第3題Thebasicmechanismofanti-inflammatoryactionofglucocorticoidis:AStabilizeslysosomemembranesBStabilizes

hypertrophiccellmembraneCImprovestolerancetobacterialendotoxinsDPlaysanti-inflammationroleprimarilythroughgenomiceffectsTestforchapter6第1題Whichisthepurposethatglucocorticoidsareusedforsevereinfection:AIncreasesthebody'stolerancetoharmfulstimuliandstrivesforrescuetimebyanti-inflammatoryeffectBInhibitsbacterialproliferationCNeutralizestoxinssecretedbybacteriaDStrengthensthemyocardialcontractilitysothatthepatientslivethroughthecrisisperiod第2題Thereasonforreboundphenomenonmediatedbythesuddenwithdrawalofglucocorticoidafterlong-termuseisthatAThepatientisdependentonglucocorticoidorthediseaseisnotadequatelycontrolledBHyperadrenocorticalfunctionCAsuddenincreaseinACTHsecretionDIncreasedglucocorticoidsecretion第3題Long-termuseofglucocorticoidsmayleadtoAHypercalcemiaBHypokalemiaCHypotensionDHypoglycemiaTestforchapter7第1題磺酰脲類藥物引起較嚴(yán)重的不良反應(yīng)是A胃腸道反應(yīng)B過敏反應(yīng)C肝損傷D持久性的低血糖反應(yīng)第2題合并重度感染的糖尿病患者宜選用A格列本脲B正規(guī)胰島素C羅格列酮D二甲雙胍第3題單用飲食無法控制的肥胖糖尿病患者宜選用A胰島素B二甲雙胍C格列喹酮D西格列汀Testforchapter8第1題Whatistheprincipalmechanismofactionofpropylthiouracil(PTU)?AIodidetransportintothecellBReleaseofT4andT3tothebloodCInhibitionofthyroidalperoxidaseDInhibitionofproteolysisofthyroglobulinEInhibitionofiodinationandcouplingofthyroglobulin第2題Whichisthedrugchoiceforthyrotoxiccrisis？Amethylthiouracil

B

propylthiouracilCthiamazoleDcarbimazoleEradioiodineTestforchapter1第1題Acquireddrugresistancerefersto:AThesensitivityofpathogenstodrugsdecreasedaftercontinuousadministrationBThesensitivityofthebodytodrugsdecreasedaftercontinuoususeofdrugs.CThepatientispsychologicallydependentonthedrug.DThepatientdevelopedaphysicaldependenceonthedrug.EPatientshavementalandphysicaldependenceondrugs.第2題Whichisthedrugwhoseresistancecanbeinducedbyβ-lactamases:AfluroquinolonesBsulfonamidesCaminoglycosidesDampecilinEtetracyclinesTestforchapter2第1題β-lactamantibioticsDONOTincludeAPGBSemisyntheticpenicillinsCCephalosporinsDGlycopeptidesEβ-lactamaseinhibitor第2題DrugsthatcanNOTinhibitbacterialcellwallincludeAPGBSemisyntheticpenicillinsCCephalosporinsDGlycopeptidesEβ-lactamaseinhibitor正確答案：E第3題TheresistancemechanismsofpenicillinDONOTincludeAmutationofPBPsBproducingβ-lactamaseCdecreaseddrugaccumulationinbacteriumDreducedbindingaffinityofthedrugEdestroyingthestructureofβ-lactamTestforchapter3第1題TheresistancemechanismsoferythromycinDON`TincludeAproducingβ-lactamaseBeffluxdrugCmethylationmodificationofbacterialribosomeDdecreaseddrugaccumulationinbacteriumEmetabolizingandinactivatingdrugTestforchapter4第1題Whichoneofthefollowingis