1、,Connective Tissue 劉佳梅,Component: cell and intercellular substance (fibers and matrix) Connective tissue: Connective tissue proper Cartilage, bone Blood,Origin: mesenchyme,Connective tissue proper,LCT DCT CT Adipose tissue Reticular tissue,. Loose connective tissue,collagen fibers fiber elastic fibe

2、rs reticular fibers intercelullar substance matrix LCT fibroblast macrophage plasma cell mast cell cells adipocyte white blood cell undifferentiated mesenchymal cell,1. Cells of the connective tissue,1.1 Fibroblasts,1.1 Fibroblasts,EM: RER , Free Ribosomes Golgi apparatus Function: synthesis of fibe

3、rs and amorphous ground substance,1.1 Fibroblasts,Fibrocytes: inactive fibroblasts,1.2 Macrophages,LM: irregular shape with pseudopodia, small and dark nucleus, strong acidophilic cytoplasm.,Origin: monocytes Function: Chemotaxins Phagocytosis Secretion Immune reaction,1.2 Macrophages,1.2 Macrophage

4、s,1.3 Plasma cells,LM:,Origin: B lymphocyte Function: produce antibodies,1.3 Plasma cells,1.4 Mast cells,LM:,EM: Function: involved in allergic reactions,1.4 Mast cells,1.5 Fat cells 1.6 Undifferentiated cells 1.7 Leukocytes,2Fiber,（）collagen fiber collagen fibril: type I collagen,（2） Elastic fibers

5、,Component: elastin and microfibrils Function: elasticity,(3) Reticular fibers,Component: type III collagen Function: give support to individual cells,3. Ground substance,3.1 proteoglycan(蛋白聚糖) Proteoglycan are composed of a core protein associated with 4 main glycosaminoglycans(氨基聚糖).,3.2 fibronect

6、in 3.3 tissue fluid,. Dense connective tissue,1. Dense regular connective tissue the collagen fibers are parallel to each other. Fibroblasts are located between fibrous bundles.,2. Dense irregular connective tissue,The collagen fibers are arranged in bundles without a definite orientation.,3. Elastic Tissue,Elastic tissue is composed of bundles of thick, parallel elastic fibers.