1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEVitamin B12Cat. No.: HY-B0315CAS No.: 68-19-9Synonyms: Cyanocobalamin分式: CHCoNOP分量: 1355.37作靶點(diǎn): Endogenous Metabolite作通路: Metabolic Enzyme/Protease儲(chǔ)存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (protect

2、fromlight)溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 25 mg/mL (18.45 mM; Need ultrasonic)H2O : 12 mg/mL (8.85 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 0.7378 mL 3.6890 mL 7.3781 mL5 mM 0.1476 mL 0.7378 mL 1.4756 mL10 mM 0.0738 mL 0.3689 mL 0.7378 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)

3、驗(yàn) 請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍福渲魄罢?qǐng)先配制澄的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (1.84 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (1.8

4、4 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 Vitamin B12溶性維素，在維持腦、神經(jīng)系統(tǒng)正常功能和流形成等發(fā)揮關(guān)鍵作。IC50 & Target Human Endogenous MetaboliteREFERENCES1. /wiki/Vitamin_B122. Banerjee, R. and S.W. Ragsdale, The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annu Rev Biochem,2003. 72: p. 209-47.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fa