Hotline:400-820-3792Inhibitors?Agonists?ScreeningLibrarieswww.MedChemEResveratrolanalog1Cat.No.:HY-136203CASNo.:861446-16-4分?式:C??H??FO?分?量:230.23作?靶點:IKK;Autophagy;Mitophagy;Sirtuin作?通路:NF-κB;Autophagy;CellCycle/DNADamage;Epigenetics儲存?式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實驗DMSO:100mg/mL(434.35mM;Needultrasonic)H2O:<0.1mg/mL(insoluble)MassSolvent1mg5mg10mgConcentration制備儲備液1mM4.3435mL21.7174mL43.4348mL5mM0.8687mL4.3435mL8.6870mL10mM0.4343mL2.1717mL4.3435mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存?式和期限。體內(nèi)實驗請根據(jù)您的實驗動物和給藥?式選擇適當(dāng)?shù)娜芙?案，配制前請先配制澄的儲備液，再依次添加助溶劑(為保證實驗結(jié)果的可靠性，體內(nèi)實驗的?作液，建議您現(xiàn)?現(xiàn)配，當(dāng)天使?；澄的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分?指該溶劑在您配制終溶液中的體積占?)：1.請依序添加每種溶劑：10%DMSO>>40%PEG300>>5%Tween-80>>45%salineSolubility:5mg/mL(21.72mM);Suspendedsolution;Needultrasonic2.請依序添加每種溶劑：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:5mg/mL(21.72mM);Suspendedsolution;Needultrasonic3.請依序添加每種溶劑：10%DMSO>>90%cornoil1/2MasterofSmallMolecules—您?邊的抑制劑?師www.MedChemESolubility:≥5mg/mL(21.72mM);ClearsolutionBIOLOGICALACTIVITY?物活性Resveratrolanalog1?藜蘆醇(HY-16561)的類似物(analog)，化合物48。?藜蘆醇?種天然的多酚類植物抗毒素，具有抗氧化、抗炎、保護?臟和抗癌的特性。IC50&TargetIC50:Resveratrolanalog[1]REFERENCES[1].Liu,Jing,"SynthesisofResveratrolandItsAnalogs,Phase-TransferCatalyzedAsymmetricGlycolateAldolReaction,andTotalSynthesisof8,9-Methylamido-Geldanamycin"(2007).AllThesesandDissertations.1415.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-58