()

ACNU

25mg 5ml,50mg

10ml ，

25mg50mg

BCNU

125mg

250ml, 1-2h

125mg

CCNU

40mg100mg

CTX

400-1000mg/m2,

3h

50mg

100mg200mg

IFO

7-10g/n2 3-5

.

0.5g1g2g

M-25

Me-CCNU

50mg

5'-DFUR

.

100mg200mg

5-

5-FU

6-

6-MP

25mg50mg

6-TG

Ara—C

100mg//m2,12h1

,5-10; B

50mg100mg

FNDR

5-FU ， 2-3

5-6.

125-500mg,

250mg

FT-207

5-FU,

Gemzer

1000mg〃m2 30min,

， 3,4 ，

CDDF.

200mg1000mg

HCFU

HU

MTX

5mg0.1g1.0g

UFT

FT-207 1:4

Ara-C

D

ACD

K .

， 1%

， 50-100mg

200g

ADM

40-60mg/m2, 2 21

5-Fu .

DRN

, ,

EPI

60-80mg/m2 3 3,3

.5mg 25ml ,

10mg

MMC

20mg/n2,6-8 .

6….

2mg4mg

ADM

PLMPEP

30min

A5

A5

PYM

THPTHP-ADM

CPT-11

24h

,,

0.25mg/2h.5-FU.

， 4.

5ml/100mg

，

80-90%

HHRT

.

Hydroxycamptothecin

： 6-8mg/m2,

7-10,21

10-12mg/n2, 2， 2 1

,3 .

NVB

,

Taxol

135mg/n2

3h. 12 6h,

20mg;30-60min

50mg .

50mg.

Taxotere

TopotecanHCI

VCR

1 .

2mg.

1mg

VDS

VLB

VM-26

VP16

,

0.1-0.4mg/ml，

30min.

50mg100mg.

100mg

.

Arimidex

Elipten

.

250mg

Femara

.

Lentaron

, .

250mg

MA

TAM

3，

4，

40mg.

40mg

ASP

10-50IU0.1ml ， 5h,

.

1000IU10000IU

CBP

PDD .

. .

Calvert . =AUCx

( +25).AUC

， 5-7.

(ml/min)=(140- )x /72X

(mg/100ml).

100mg

0.85.

DDP

， :PDD

12h

2000ml:PDD

3000-3500ml,

，

2000-3000ml.

.

10mg20mg30mg

1-2h, 2-3.

.

.

DTIC

.

200mg

Eloxatin

+LV+5-FU

130-135mg/m2, 2-6,3

Calvertmg=AUCx( +25). 5-

FU 5-FU.

i

MIT

, ,

5mg10mg20mg30mg

PCB

()

Ancitabine

Hydroxycamptothecin

.

5'-DFUR

Doxifluridine

.

5-

5-FU

Fluorouracil

, ,

6-

6-MP

Mercaptopurine

6-TG

Tioguanine

ANLL Ara-C

D

ACD

Dactinomycin

ACNU

Nimustine

ADM

Doxorubicin

SCLC

Wilms

Ara-C

Cytarabine

ANLL

Arimidex

Atmestane

ASP

Asparaginase

ES-2

BCNU

Carmustine

,

CBP

Carboplatin

.

CCNU

Lomusitine

MML )

CPT-11

Irinortecan

.NSLCLSCLC

CTX

Cyclophosphamide

（NHL

DDP

Cisplatin

.

DRN

Daunorubicin

AML

DTIC

Dacarbazine

.

Elipten

Aminoglutethimid

.

Eloxatin

Oxaliplatin

.

EPI

Epirubicin

NHL

SCLC

Femara

Letrozol

.

FNDR

Floxuridine

HAL

FT-207

Gemzer

Gemcitabine

.

HCFU

Carmoful

Ara-C

HHRT

Homoharringtonin

.

HU

IFO

Ifosfamide

Lentaron

Formesten

.

M-25

Glyciphosphoramide

SCLC

MA

Megestrol

（QQL）.

Me-CCNU

Semustine

MIT

Mitoxantrone

.

MMC

Mitomycin

， .5-FU

ADMMM .

MTX

Methotrexate

， NHL

NVB

Vinorelbine

NSCLC

PCB

Procarbazine

PLM

PEP

Peplomycin

.

A5

A5

PYM

BleomycinA5

.

TAM

Tamoxifen

TAM+PDD ,

53%.

,

Taxol

Paclitaxel

.

Taxotere

Docetaxel

.

THP

THP-ADM

Pirarubicin

Topotecan

HCI

Topotecan

SCLCNSCLC.

UFT

.