1、C.Xianhua Yang, Lallemand Animal Nutrition拉曼動(dòng)物營(yíng)養(yǎng)公司Shangai, Monday, September 6th, China - 上海, 星期一, 九月六日, 中國(guó) - How to reduce the production cost by using probiotics? -如何利用添加益生菌來降低生產(chǎn)成本? -Animal Nutrition and HealthPiglet仔豬Sow母豬The farm environment飼養(yǎng)場(chǎng)環(huán)境house房舍room豬圈Pen圈養(yǎng)room豬圈ENVIRONNEMENT環(huán)境House房舍MEAT

2、 QUALITY豬肉質(zhì)量FEED HYGIENE飼料衛(wèi)生DIGESTIBILITY消化率DIGESTIVE SECURITY消化安全性We are feeding intestinal ecosystem, not host animals !我們是在喂養(yǎng)腸道菌群生態(tài)系統(tǒng), 而不是宿主動(dòng)物 !Remember切 記“Digestive flora is a real organ. It acts on animal metabolism & immunity by exerting a nutritional, antibacterial and immunological role” Pro

3、f. Griess, former UE SCAN member, ENV Toulouse.“消化道菌群是真實(shí)存在的有機(jī)體. 它們通過發(fā)揮營(yíng)養(yǎng)、抗菌和免疫作用來調(diào)節(jié)動(dòng)物的新陳代謝和免疫功能” Griess教授, 前 UE SCAN 成員,圖盧茲國(guó)立獸醫(yī)學(xué)校（ENV Toulouse）.Good management of these processes is vital for the growth and well-being of the host animal處理好這些過程對(duì)宿主動(dòng)物的生長(zhǎng)和健康至關(guān)重要1014 living micro-organisms(10 000 times w

4、orld population)1014個(gè)活的微生物(相當(dāng)于世界總?cè)丝诘?0 000倍)200 different species200種不同的種類Digestive tract sterile at birth出生時(shí)消化道無菌Digestive ecosystem open on the outside消化系統(tǒng)通向外界Piglet microflora幼豬的微生物菌系 Example of action of probiotics on microbial micro-ecosystem:益生菌對(duì)微生物的微生態(tài)系統(tǒng)作用實(shí)例:1/ Digestive Security : the yeast

5、Levucell SB 來福喜, 消化安全性 : 酵母菌添加劑來福喜2/ The lactic ferment Bactocell 乳酸酵素百得喜 The shield effect of Levucell SB 來福喜 in 3 actions in the intestine:Levucell SB 來福喜 在腸道中發(fā)揮屏蔽作用的三種方式:Neutralization of toxins of Clostridium diffcileS.c. boutlardii protease inhibits the effects of Clostridium difficile toxins A

6、 and B in intestinal mucosa and helps to limit diarrhea (1)中和艱難梭菌的毒素S.c. boutlardii蛋白酶能夠抑制腸粘膜上的艱難梭毒素A和B發(fā)揮作用，有助于防止腹瀉發(fā)生 (1)Adherence of flagellate bacteria Binding of flagellate bacteria such as Escherichia coli, Salmonella spto S.c.boulardii cell wall and elimination of complex in faeces(2).鞭毛類細(xì)菌的粘附

7、鞭毛類細(xì)菌如Escherichia coli, Salmonella sp與S.c.boulardii細(xì)胞壁的結(jié)合，通過殘?jiān)呐懦鲶w外(2).ADHERENCE粘 附NEUTRALIZATION中 和REINFORCEMENT增 強(qiáng)Reinforcement of mucosa and intestinal wall cell integrity S.c.boulardii stimulates enzymatic activity (3),improves epithelial cell maturity(villi and crypts)and enhances the animals g

8、rowth (4).加強(qiáng)粘膜和腸壁細(xì)胞的完整性 S.c.boulardii 能夠刺激酶活性(3),促進(jìn)上皮細(xì)胞成熟（絨毛和隱窩）進(jìn)而促進(jìn)動(dòng)物生長(zhǎng)(4).The boulardii strain has been documented in more than 135 scientific publications: Boulardii菌株已被135種科學(xué)出版物所記錄Levucell SB 來福喜 Optimizes piglet growth performances and sow productivity Levucell SB 來福喜 能完善幼豬的生長(zhǎng)行為和母豬的產(chǎn)仔能力Sow prog

9、ramResults based on trials with more than 248 sows and their 2500 pigletsSow and piglet program對(duì)母豬和仔豬的研究*Trial results from the European registration file.directive 70524EC.*試驗(yàn)結(jié)果來自歐洲注冊(cè)文件指導(dǎo) 70524EC.Levucell SB 來福喜 is compatible with antibiotics and acidifiers.Levucell SB 來福喜 能夠與抗生素和酸化劑合用.Results base

10、d on trials with more than 248 sows and their 2500 piglets該結(jié)果基于248多頭母豬及它們的2500多頭豬崽試驗(yàn)所得-Less weight loss in sows during lactation:4 to 7 kg-哺乳期母豬體重?fù)p失較少:4 to 7 kg-Average increased intake per sow during lactation:+8 kg-哺乳期每頭母豬平均增加采食量:+8 kg -Heavier pigs at weaning :+5 to 9%-Increased daily weight gain

11、 for piglets post weaning:+6 9%-Better digestive integrity of piglets-斷奶時(shí)的仔豬體重 :+5 to 9%-斷奶后仔豬日增重增加:+6 9%-仔豬消化完整性更好Week周Months月Week周Farrowing分 娩Gestation妊 娠Weaning斷 奶Post-weaning斷 奶 后Improves sow body condition and productivityImpact of Levucell SB 來福喜 on weight evolution in sows (+5.4kg)Levucell SB

12、 來福喜對(duì)母豬體重變化的影響 (+5.4kg)Controlp0.036kgGestation妊 娠Farrowing分 娩Weaning斷 奶Levucell SB 來福喜- 0.67- 0.56Impact of Levucell SB 來福喜 on neonatal mortality in piglets per sow Levucell SB 來福喜對(duì)每頭母豬新生仔豬死亡率的影響Control對(duì)照Levucell SB 來福喜Control對(duì)照with positive consequences on DLWG in pre-weaning對(duì)斷奶前窩日增重的積極影響 Cycle 1

13、Cycle 2SCEA Cormier, Fce GAEC les Collines, FceEarl Gautellerie, Fce Cycle 1 Cycle 2 Cycle 1 Cycle 2ns p0.001 p0.001 p0.001 p0.001 p 2kg / ton feed 1 2kg / 噸飼料 10.56+ 559.5Cost of BactocellBactocell 成本-0.83 832.5GROSS MARGIN毛利3868.5Data: (The agricultural Budgeting & costing book, 58th edition, May

14、2004)20.3 piglets per year (after 4.5% mortality) 54 per 35kg weanerConsumption rate: 185kg / pig from 35 to 115 kg 0.2p/kg = 23.25/pigFeed conversion ratio (FCR) of 2.7 for 105 days finishing with DLWG=765g/day115 kg liveweight = 87 kg dead weight 1.47p/kgGross margin per pig = 19.77Lactic acid Pri

15、ce: 1.40 2kg / Ton feed數(shù)據(jù): (農(nóng)業(yè)預(yù)算與成本簿記, 第58版, 五月， 2004)每年20.3只仔豬 (除去已死亡的4.5%后) 54 每35kg 斷奶仔豬飼料消耗量: 185kg / 豬從35到115 kg 0.2p/kg = 23.25/豬105天飼養(yǎng)結(jié)束后飼料轉(zhuǎn)換率 (FCR)為2.7, DLWG=765g/天115 kg 活重 = 87 kg 死重 1.47p/kg每頭豬毛利 = 19.77乳酸價(jià)格: 1.40 2kg / 噸飼料Worth an extra 3868.for 1000 pigs1000頭豬增值3868歐元. 對(duì)照組來福喜活仔數(shù) / 窩8.29

16、.58哺乳期間的腹瀉率%13.86.6仔豬DWG 0 24天 (克/天)194.5202.2斷奶均個(gè)體重 (24天) 6.16.2FCR 0 24天0.210.16廣東省, 中國(guó), 2003 試驗(yàn)周期 : 10 11月 2003 (妊娠和泌乳期) 試驗(yàn)動(dòng)物 : 34 頭母豬和其所產(chǎn)小豬 分組 : 2 組 : 對(duì)照組和來福喜20 來福喜添加量 : . 母豬 : 80克/噸 (1.6.109 cfu/公斤飼料 ), 產(chǎn)仔前12 天到整個(gè)泌乳期 仔豬 : 150克/噸 (3.109 cfu/公斤飼料) 從出生到24日齡（ 斷奶)母豬和仔豬來福喜降低泌乳期腹瀉和死亡率，促進(jìn)小豬的生長(zhǎng) 對(duì)照組來福喜仔豬

17、日增重 (0 24天)哺乳期間的腹瀉率g/day- 5.3%+ 3.9 %斷奶時(shí)仔豬均重kg+ 1.38% diarrhoea窩均產(chǎn)活仔數(shù)Nb of pigletsLevucell in China 來福喜對(duì)照組來福喜均產(chǎn)活仔數(shù) / 窩9.29.5初生均重 0天 (公斤)12.114斷奶頭數(shù)133162窩日增重 (克/天) 0 28天20812175北京資源亞太種豬有限公司 , 中國(guó), 2004 試驗(yàn)周期 : 2 4月 2004 (妊娠和泌乳期) 試驗(yàn)動(dòng)物 :40 頭母豬和其所產(chǎn)小豬 分組 : 2 組 : 對(duì)照組和來福喜20 來福喜添加量 : . 母豬 :50克/噸 (1.109 cfu/公斤

18、飼料 ), 產(chǎn)仔前20天到整個(gè)泌乳期 仔豬 : 100克/噸 (2.109 cfu/公斤飼料) 從出生到28日齡（ 斷奶) 母豬和仔豬來福喜促進(jìn)斷奶前仔豬的生長(zhǎng) 對(duì)照組來福喜窩日增重 (0 28天)初生窩均重g/day+ 1.9+ 4.2 %斷奶頭數(shù)+ 0.3kg窩均產(chǎn)活仔數(shù)Nb of pigletsLevucell in China 來福喜Tells me that if you use the right strain, the right dose, the right time and the right treatment length you can obtain very fine results.告訴我如果你使用了正確的菌株, 恰當(dāng)?shù)膭┝? 在適宜的時(shí)候，給予恰當(dāng)周期的益生菌添加劑，你肯定會(huì)取得非常好的效果.Dr Niels Hjornholm