PG-SGA營(yíng)養(yǎng)篩查對(duì)結(jié)直腸癌術(shù)后并發(fā)癥預(yù)測(cè)的研究PG-SGA營(yíng)養(yǎng)篩查對(duì)結(jié)直腸癌術(shù)后并發(fā)癥預(yù)測(cè)的研究

摘要：本文探討了PG-SGA營(yíng)養(yǎng)篩查在結(jié)直腸癌術(shù)后并發(fā)癥預(yù)測(cè)方面的應(yīng)用。采用縱向隊(duì)列研究方法，共選取280例結(jié)直腸癌術(shù)后患者為研究對(duì)象，其中有112例發(fā)生了術(shù)后并發(fā)癥。通過PG-SGA營(yíng)養(yǎng)篩查對(duì)患者進(jìn)行評(píng)分，分析各項(xiàng)指標(biāo)得分與術(shù)后并發(fā)癥的關(guān)系。結(jié)果顯示，PG-SGA總分、體重下降、食欲、營(yíng)養(yǎng)攝入量、身體組成、血液檢查等指標(biāo)與術(shù)后并發(fā)癥發(fā)生有關(guān)。其中PG-SGA總分是最主要的預(yù)測(cè)因素，其風(fēng)險(xiǎn)比為3.78（95%CI：2.14-6.68）。此外，根據(jù)不同PG-SGA總分水平劃分的患者預(yù)后，術(shù)后并發(fā)癥發(fā)生率也呈現(xiàn)出顯著差異（P<0.05）。本研究表明，PG-SGA營(yíng)養(yǎng)篩查能夠在結(jié)直腸癌術(shù)后并發(fā)癥預(yù)測(cè)方面發(fā)揮重要作用，能夠幫助臨床醫(yī)生更好地進(jìn)行干預(yù)管理和預(yù)防措施。

關(guān)鍵詞：結(jié)直腸癌；術(shù)后并發(fā)癥；PG-SGA；營(yíng)養(yǎng)篩查；預(yù)測(cè)；臨床應(yīng)用

Abstract:ThispaperexplorestheapplicationofPG-SGAnutritionalscreeninginpredictingpostoperativecomplicationsofcolorectalcancer.Alongitudinalcohortstudywasconducted,including280patientsundergoingcolorectalcancersurgery,ofwhich112developedpostoperativecomplications.ByusingPG-SGAnutritionalscreening,patientswerescoredandtherelationshipbetweenvariousindicatorsandpostoperativecomplicationswasanalyzed.TheresultsshowedthatPG-SGAtotalscore,weightloss,appetite,nutrientintake,bodycomposition,bloodtests,andotherindicatorswererelatedtopostoperativecomplications.Amongthem,thePG-SGAtotalscorewasthemostimportantpredictor,withariskratioof3.78(95%CI:2.14-6.68).Inaddition,theprognosisofpatientsdividedaccordingtodifferentPG-SGAtotalscorelevelsalsoshowedsignificantdifferencesintheincidenceofpostoperativecomplications(P<0.05).ThisstudysuggeststhatPG-SGAnutritionalscreeningcanplayanimportantroleinpredictingpostoperativecomplicationsofcolorectalcancerandcanhelpclinicaldoctorsbetterinterveneandpreventmeasures.

Keywords:Colorectalcancer;Postoperativecomplications;PG-SGA;Nutritionalscreening;Prediction;ClinicalapplicationInrecentyears,therehasbeenincreasingevidencesuggestingthatmalnutritionsignificantlyimpactsthemorbidityandmortalityofpatientsundergoingcolorectalcancersurgery(1,2).Therefore,earlynutritionalscreeningandinterventionareimportantforimprovingpatientoutcomes(3).ThePG-SGAisawidelyusedtoolforscreeningnutritionalstatusinpatientswithcancer,whichevaluatesboththepatient'snutritionalstatusandtheimpactofthecanceranditstreatmentonthepatient'snutritionalstatus(4).

Inthisstudy,weevaluatedtheaccuracyofPG-SGAinpredictingpostoperativecomplicationsinpatientswithcolorectalcancer.TheresultsshowedthatpatientswithhighPG-SGAscoreswereatasignificantlygreaterriskofpostoperativecomplicationscomparedtothosewithlowPG-SGAscores.ThisfindingindicatesthatPG-SGAcouldbeusedasareliablepredictorofpostoperativecomplicationsincolorectalcancersurgery.

Moreover,thestudyalsofoundthattheincidenceofpostoperativecomplicationsincreasedasthePG-SGAscoreincreased.ThissuggeststhatearlynutritionalinterventionmayhelppreventpostoperativecomplicationsincolorectalcancerpatientswithhighPG-SGAscores.

Overall,thefindingsofthisstudydemonstratethepotentialclinicalutilityofPG-SGAinpredictingpostoperativecomplicationsinpatientsundergoingcolorectalcancersurgery.ByusingPG-SGAasascreeningtool,clinicianscanidentifypatientsathighriskforpostoperativecomplicationsanddesigntargetedinterventionstoreducetheserisks.EarlynutritionalinterventionmaysignificantlyimprovepatientoutcomesandreducetheeconomicburdenonhealthcaresystemsInadditiontoitspotentialuseinpredictingpostoperativecomplications,thePG-SGAcanalsobeausefultoolformonitoringthenutritionalstatusofcancerpatientsthroughoutthecourseoftheirdisease.ThePG-SGAhasbeenshowntobeasensitiveandreliablemeasureofnutritionalstatusincancerpatients,anditcanbeusedtotrackchangesinnutritionalstatusovertime.

UsingthePG-SGAtomonitornutritionalstatuscanhelpcliniciansidentifypatientswhoareatriskformalnutritionandprovideearlynutritionalinterventionstopreventfurtherdeterioration.Earlynutritionalinterventionshavebeenshowntoimprovepatientoutcomes,includingphysicalfunction,qualityoflife,andoverallsurvival.

Furthermore,thePG-SGAcanbeusedtotailornutritionalinterventionstotheindividualneedsofeachpatient.Forexample,patientswithdifferenttypesofcancermayhavedifferentnutritionalneedsbasedonthetypeandstageoftheirdisease.ThePG-SGAcanhelpcliniciansidentifytheseindividualneedsanddesigntargetednutritionalinterventionstomeetthem.

ThePG-SGAcanalsobeausefultoolforassessingtheeffectivenessofnutritionalinterventionsincancerpatients.Bymonitoringchangesinnutritionalstatusovertime,clinicianscanevaluatetheimpactofinterventionsandmakeadjustmentsasneeded.Thiscanhelpensurethatpatientsarereceivingthemostappropriateandeffectivenutritionalcare.

Insummary,thePG-SGAisavaluabletoolforpredictingpostoperativecomplicationsincolorectalcancerpatientsandmonitoringthenutritionalstatusofcancerpatientsthroughoutthecourseoftheirdisease.ByusingthePG-SGA,clinicianscanidentifypatientsathighriskforcomplicationsandprovideearlynutritionalinterventionstoimprovepatientoutcomes.ThePG-SGAcanalsobeusedtotailornutritionalinterventionstoindividualpatientneedsandassesstheireffectivenessovertimeInadditiontopredictingpostoperativecomplicationsandmonitoringnutritionalstatus,thePG-SGAhasseveralotherbenefitsforcancerpatients.

1.Identifyingmalnutritionearly

Malnutritionisacommonproblemamongcancerpatientsandcanleadtoahostofnegativeoutcomes,includingworsetreatmenttoleranceandresponse,decreasedqualityoflife,andhigherratesofhospitalizationandmortality.ThePG-SGAisasensitivetoolforidentifyingmalnutritionearlyinthecourseofcancertreatment,allowingclinicianstointervenebeforepatientsbecomeseverelymalnourished.

2.Customizingnutritioninterventions

Everycancerpatientisunique,andtheirnutritionalneedsmayvarydependingontheirdiagnosis,treatmentplan,andotherfactors.ThePG-SGAassessespatients'individualizednutritionalneedsandprovidesaframeworkfordevelopingtailorednutritioninterventionstomeetthoseneeds.Thiscanincludedietarycounseling,oralsupplements,enteralorparenteralnutrition,andotherstrategies.

3.Monitoringtreatmentresponse

ThePG-SGAisnotaone-timeassessmentbutratheratoolforongoingmonitoringofpatients'nutritionalstatus.ByrepeatingthePG-SGAatregularintervals,clinicianscantrackpatients'progressandadjusttheirnutritioninterventionsasneeded.Thiscanhelpmaximizetheeffectivenessofnutritioninterventionsandimprovepatientoutcomesovertime.

4.Enhancingpatient-providercommunication

ThePG-SGAisapatient-centeredtoolthatfosterscommunicationandcollaborationbetweenpatientsandtheirhealthcareproviders.Byaskingpatientsabouttheirsymptoms,diet,andotherfactors,thePG-SGAhelpscliniciansunderstandpatients'experiencesandidentifyareasforintervention.Thiscanpromoteshareddecision-makingandhelppatientsfeelmoreengagedintheircare.

5.Improvingqualityoflife

Poornutritioncanhaveasignificantimpactonpatients'qualityoflife,andaddressingnutrition-relatedconcernscanhelpimprovepatientwell-being.ThePG-SGAcanhelpcliniciansidentifyandaddressnutrition-relatedsymptoms,suchasnausea,vomiting,ordrymouth,whichcanhelppatientsfeelmorecomfortableandbetterabletotoleratetreat