在我國老年人中的發(fā)生率約為8.5%[1],且逐漸呈現(xiàn)年輕化的趨勢(shì)[2]。K0A嚴(yán)重運(yùn)動(dòng)學(xué)習(xí)、再學(xué)習(xí)和軀體調(diào)節(jié)以及平衡維持中發(fā)揮關(guān)鍵作用。然而在老年K0A膝關(guān)節(jié)的本體感覺主要依賴于關(guān)節(jié)囊中的機(jī)械感受器(魯菲尼小體、高爾基維持膝關(guān)節(jié)的穩(wěn)定性時(shí)，由于K0A患者股四頭肌肌力較弱[11],因此表現(xiàn)為其他疼痛還會(huì)導(dǎo)致腦部結(jié)構(gòu)功能的改變，呈現(xiàn)出N-乙酰天冬氨酸(一種感覺恢復(fù)的重要靶點(diǎn)之一。然而盡管如口服非類固醇抗炎藥(雙氯芬酸鈉緩釋膠囊)、關(guān)節(jié)注射等可有效緩解K0A患者疼痛的療衰老引起的外周和中樞神經(jīng)系統(tǒng)改變，將導(dǎo)致本體感覺通是老年人平衡的重要決定因素[16],而隨著年核心肌肉逐漸變薄[17],這也將減弱老年人對(duì)自身軀體的控制能力。上述綜合因1.本體感覺訓(xùn)練：本體感覺訓(xùn)練是KOA本體感覺康復(fù)重建的對(duì)中樞神經(jīng)系統(tǒng)的累積神經(jīng)輸入[19],達(dá)到恢0],一般需包含肌力訓(xùn)練(如等速肌力訓(xùn)練等)[21]、本體感覺神經(jīng)肌肉促進(jìn)技術(shù)4.全膝關(guān)節(jié)置換術(shù)：全膝關(guān)節(jié)置換術(shù)(TKA)是終末期K0A的有效治療方法之非視覺的控制[35],但最近的研究證實(shí)，中樞神經(jīng)系統(tǒng)可使用與平衡控制相結(jié)合的感覺刺激來補(bǔ)償另一種減弱的感覺輸入[36],如采用虛擬現(xiàn)實(shí)技術(shù)(VR)干預(yù)[3本體感覺信號(hào)輸入的缺損是導(dǎo)致老年K0A患者本體感覺減退發(fā)生的根本原A研究中應(yīng)加強(qiáng)對(duì)患者本體感覺情況的關(guān)注，亟atickneeosteoarthritisamongtheChinesepopulation:analysige,2011,19(4):381-388.DOI:10.1016/j.joca.2011.01.003.erformanceinanteriorcruciateligament-deficientsofaperturbation-basedneuromusculartrainingprogramondynamicbnofposturalcontrolwithmusclestrength,propriotweenmusclestrength,bilityinpatientswithunilateralkneeosteoarthritis[J].FrontBioeontrolamongChinesesenior[14]HenryM,BaudryS.Amplicationsforposturalcontrol[J].JNeurophysiol,2019,122(2):52[16]0zkal?,KaraM,TopuzS,etal.Asssonographicstudy[J].AgeAge[17]0taM,IkezoerchGerontolGeriatr,2012,55(XuD,TaoT,ZhangJR,etal.Theeffectofproprioceptivetrainonkneejointrecoreryamongpatientswithtotalkneereplacement:ameta-analysisofrandomizedcontrolledtrials[J].ChinJGeriatr,201[19]Ashton-MillerJA,WojtysArthrosc,2001,9(3):128-136.DOI:10.1007/s001670100208.closedkineticchainexerciseinpatientswithkneeosteoarthritis[21]KusG,Tarak?iE,RazakOzdiingversusresistancetraininginthetreatmentofkneeosteoarthritis:arandomizedcontrolledtrial[J].Cliduringstairascending:arandomizedcontrolledtrial[J].AMedRehabil,2022,101(8):753-760.DOI:10.1097/PHM.0000000000001906.[23]InceB,GokselKaratepeA,AkcayS,etal.Theefficacyofthritis:arandomizedcontrolledstudy[J].ClinRehabil,2023,37(1):60-71.DOI:10.1177/026921izedcontrolledtrials[J].JAthlTrain,2010.4085/1062-6050-329-17.ysis[J].ArchPhysMedRehabil,2019,100(6):1102-1113.DOI:/j.apmr.2018.07.425.[26]WangY,WuZ,ChenZ,etal.PoprioceptionandjointfunctioninpatientswithkneeosteoarthritisLiJF,ZhangJ,Hei進(jìn)展，2021,21(22):4275-4278,4297.DOI:10.13241/ki.pmb.2021.2YinN,TangFW,FuF,etal.Effectsoflowintensitypulsedfocusedproprioception,qualityoflifeandinflammatoryfactorslevelsinp2021,21(22):4275-4278,4297.DOI:10.13241/ki.pmb.2021.2trial[J].BMCMusculoskeletDisord,2020,21(1):582.DOI:10.1186/arthroplastyinpatienoception.Asystematicreviewandbestevidencesyplasty,2019,34(11):2815-2822.DOI:10.1016/j.nfluencekneejointproprioception?Alongitudinalprospectivestudycomparingtotalandunicompartmentalarthroplasty[J].Knee,2007,14[34]WodowskiAJ,SwiglerCW,Liuarthroplasty:aliterature301-309.DOI:10.1016/j.ocl.2015.09hemeasurementofspontaneousswaybyposturography[J].hs.2018.09.010.[37]RenY,LinC,ZhouQ,etal.Effectivenessofvamesinimprovingphyslance-impairedolderadults:asArch