MedicalBiochemistry知到課后答案智慧樹章節(jié)測(cè)試答案2025年春溫州醫(yī)科大學(xué)第一章單元測(cè)試

Whichsetofaminoacidscanabsorb280nmUVlight?（）

A:Cys&HisB:Trp&TyrC:Glu&AspD:Met&CysE:Thr&His

答案:Trp&TyrWhichofthefollowingaminoacidsisinvolvedintheformationofdisulfidebridge?（）

A:tryptophanB:CysteineC:methionineD:hydroxyprolineE:tyrosine

答案:CysteineTheformationofproteinsecondarystructureismainlydependenton（）

A:base-stackinginteractionB:disulfidebondC:hydrophobicpackingD:hydrogenbondE:peptidebond

答案:hydrogenbondEssentialofproteindenaturationis（）

A:breakofpeptidebondsB:damageofprimarystructureC:ruptureofdisulfidebondD:breakofnon-covalentbondsE:ruptureofhydrogenbonds

答案:breakofnon-covalentbondsTheaminoacidwhichdoesnotexistinnaturalproteinsis（）

A:lysineB:cysteineC:methionineD:glycineE:citrulline

答案:citrulline

第二章單元測(cè)試

ThebaseisfoundinmRNAbutnotinDNAis（）

A:GB:AC:UD:TE:C

答案:UIfthecontentofadenineis15%inaDNAdoublehelix,thatofcytosineis（）

A:75%B:85%C:55%D:35%E:15%

答案:35%Whichofthefollowingstatementsaboutnucleosomestructureiscorrect?（）

A:NucleosomesaresphericalstructurescomprisedofRNA,nonhistoneproteinsandhistoneproteins.B:Alloftheabove.C:ThemajorhistonescomprisingnucleosomesareH1andH4.D:NucleosomespermitefficientpackingofDNAtoaboutoneseventhitsnormalvolume.E:ThehistoneassociatedwiththeDNAinthelinkerregionholdingnucleosomesiscalledH2A.

答案:NucleosomespermitefficientpackingofDNAtoaboutoneseventhitsnormalvolume.ThecodoninmRNAreverselycomplementarypairingwithanti-codonUGCintRNAis（）

A:GCTB:AUGC:GCAD:ACGE:TCG

答案:GCAThe5′endofmRNAinmosteukaryoteshas（）

A:SDsequenceB:-CCAsequenceC:initiationcodonD:polyAtailE:Capstructure

答案:Capstructure

第三章單元測(cè)試

Thespecificityofenzymeisdeterminedby（）

A:coenzymeB:prostheticgroupC:metalionD:apoproteinE:Substrate

答案:apoproteinTheeffectofnon-competitiveinhibitoronenzyme-catalyzedvelocityis（）

A:Kmdecreased,VmaxunchangedB:Kmunchanged,VmaxdecreasedC:Kmdecreased,VmaxincreasedD:Kmdecreased,VmaxdecreasedE:Kmincreased,Vmaxunchanged

答案:Kmunchanged,VmaxdecreasedAnalogofsulfonamideis（）

A:folicacid(FA)B:dihydrofolicacid(DHFA)C:glutamateD:tetrahydrofolicacid(THFA)E:paraaminobenzoicacid(PABA)

答案:paraaminobenzoicacid(PABA)Thephysiologicalsignificanceofzymogenactivationis（）

A:toacceleratemetabolismB:toavoidself-damageC:toresumeenzymeactivityD:toprotectenzymeactivityE:tofacilitategrowth

答案:toavoidself-damageIftheenzymaticvelocityis90%ofVmax,[S]shouldbe（）timesofKm.

A:9B:5C:8D:4.5E:90

答案:9

第四章單元測(cè)試

WhichoffollowingvitaminscanbeconvertedintoNAD+andNADP+?（）

A:VitB12B:VitB1C:VitPPD:VitB6E:VitB2

答案:VitPPWhichofthefollowingvitamindeficienciescausesnightblindness?（）

A:VitB1B:VitAC:VitB2D:VitDE:VitE

答案:VitATheactiveformofvitaminDinthebodyis（）

A:24,25-(OH)2-vitaminD3B:25-(OH)-vitaminD3C:1,25-(OH)2-vitaminD3D:24-(OH)-vitaminD3E:1-(OH)-vitaminD3

答案:1,25-(OH)2-vitaminD3Folatedeficiencycancause（）

A:sickle-cellanemiaB:beriberiC:ScurvyD:megaloblasticanemiaE:rickets

答案:megaloblasticanemiaWhichofthefollowingvitaminscontainsthemetalcobaltatom？（）

A:VitB12B:VitPPC:VitB2D:pantothenicacidE:VitE

答案:VitB12

第五章單元測(cè)試

Whichcoenzymeinpyruvatedehydrogenasecomplexservesasthefinalhydrogensacceptor?（）

A:lipoateB:biotinC:FADD:TPPE:NAD+

答案:NAD+Whichpathwayofthefollowingisrelatedtonucleicacidssynthesis?（）

A:GluconeogenesisB:PentosephosphatepathwayC:GlycolysisD:CitricacidcycleE:Glycogenolysis

答案:PentosephosphatepathwayThedirectdonorofglucosylgroupinglycogenesisis（）.

A:GDPGB:UDPGC:CDPGD:G-1-PE:G-6-P

答案:UDPGMuscleglycogencannotreplenishbloodsugarbecausemusclecellslack（）

A:glucose-6-phosphataseB:pyruvatecarboxylaseC:pyruvatekinaseD:hexokinaseE:Phosphofructokinase-1

答案:glucose-6-phosphataseWhichofthefollowinghormonescanlowerbloodglucose？（）

A:insulinB:thyroxineC:glucocorticoidD:adrenalinE:glucagon

答案:insulin

第六章單元測(cè)試

Whichofthefollowingenzymescatalyzestheratecontrollingstepinfattyacidbiosynthesis?（）

A:deacylaseB:acetyl-CoAcarboxylaseC:synthetaseD:dehydrataseE:enoylACPreductase

答案:acetyl-CoAcarboxylaseWhichofthefollowingisanintermediateinketonebodysynthesis?（）

A:biotinB:cyanocobalamin(VitaminB12)C:citrateD:phosphopantetheineE:3-hydroxy-3-methylglutaryl-CoA

答案:3-hydroxy-3-methylglutaryl-CoAIndicatethecorrectsequenceofreactionsemployedforbeta-oxidationofacyl-CoAderivativesfromthelistbelow.（）

A:oxidationcoupledtoFAD,thiolysisoxidationcoupledtoNAD,hydrationB:oxidationcoupledtoNAD,thiolysis,oxidationcoupledtoFAD,hydrationC:oxidationcoupledtoNAD,hydration,oxidationcoupledtoNAD,thiolysisD:oxidationcoupledtoFAD,hydration,oxidationcoupledtoFAD,thiolysisE:oxidationcoupledtoFAD,hydration,oxidationcoupledtoNAD,thiolysis

答案:oxidationcoupledtoFAD,hydration,oxidationcoupledtoNAD,thiolysisHMGCoAcanactasaprecursorforallofthefollowingEXCEPT:（）

A:adrenalcorticalhormones.B:VitaminC:estrogen.D:bileacids.E:lecithin.

答案:lecithin.Fattyacidsfromadiposetissuearetransportedtositesofutilizationintheformof（）

A:verylowdensitylipoproteins.B:freefattyacidsboundtoserumalbumin.C:triglyceridesboundtoserumalbumin.D:chylomicrons.E:highdensitylipoproteins.

答案:freefattyacidsboundtoserumalbumin.

第七章單元測(cè)試

Whichofthefollowingcomponentsofthemitochondrialelectrontransportsystemareincapableofcarrying2electrons?（）

A:NAD+B:cytochromeCC:UbiquinoneD:FADE:FMN

答案:cytochromeCThemainfunctionoftheglycerolphosphateshuttleisin（）

A:anaerobicglycolysisforregenerationofNAD.B:thetransportofreducingequivalentsintomitochondriafromNADHformedduringglycolysis.C:thebiosynthesisoftriacylglycerols.D:thebiosynthesisofserineforuseinmitochondrialproteinsynthesis.E:theβ-oxidationoffattyacids.

答案:thetransportofreducingequivalentsintomitochondriafromNADHformedduringglycolysis.Theuncouplingofoxidativephosphorylationfoundinthebrownfatmitochondriaofanewborninfantmightbeofphysiologicalimportancebecause（）

A:itraisestheoxygenlevelintheblood.B:itproduceswater.C:itincreasesCO2intheblood.D:itallowsATPformationE:itproducedheat.

答案:itproducedheat.ATPsynthasecarryoutsubstratelevelphosphorylations.（）

A:對(duì)B:錯(cuò)

答案:錯(cuò)ThemitochondrialelectrontransportsystemresponsibleforreoxidationofNADHandelectrontransfertooxygenislocatedininnermembraneofthemitochondria.（）

A:對(duì)B:錯(cuò)

答案:對(duì)

第八章單元測(cè)試

AllofthefollowingareessentialaminoacidsEXCEPT（）

A:valineB:TryptophanC:serineD:lysineE:threonine

答案:serineTheaminoacidthatisinvolvedinalmosteveryaminotransferasereactionis（）

A:GlutamineB:lysineC:glutamateD:aspartateE:pyruvate

答案:glutamateThenitrogensinureaoriginateMOSTDIRECTLY(fewestnumberofsteps)from（）

A:NH3andglutamineB:carbamoylphosphateandaspartateC:NH3andglutamateD:alanineandglutamateE:freeammonia

答案:carbamoylphosphateandaspartatePyridoxalphosphateactsascoenzymeinmost（）

A:noneoftheaboveB:kinasereactions.C:carbondioxideincorporatedreactions.D:dehydrogenationreactions.E:transaminationreactions.

答案:transaminationreactions.Theprimaryfunctionoftheureacycleis（）

A:theturnoverofexcessarginineB:theproductionofthecitricacidcycleintermediatefumarateC:thesynthesisofornithineforspermidinesynthesisD:toconverttoxicammoniatoureawhichcanbeexcretedE:thesynthesisofaspartate

答案:toconverttoxicammoniatoureawhichcanbeexcreted

第九章單元測(cè)試

Whichofthefollowingisthecommonmaterialforthesynthesisofpyrimidineandpurinenucleotide?（）。

A:FormicacidB:GlutamineC:GlycineD:Fumarate

答案:GlutamineWhichofthefollowingsubstancedirectlylinksnucleotidesynthesisandglucosemetabolism?（）。

A:GlucoseB:Glucose-6-phosphateC:Ribose-5-phosphateD:Glucose-6-phosphate

答案:Ribose-5-phosphateWhichofthefollowingisnotaphysiologicalroleofnucleotide?（）。

A:carriersofchemicalenergyB:componentsofmanyproteinsC:componentsofthecoenzymesFADandCoAD:intermediatesforbiosyntheticprocesses

答案:componentsofmanyproteinsTheprincipalnitrogenousurinaryexcretionproductinhumansresultingfromthecatabolismofAMPis（）

A:thiamineB:creatinineC:uricacidD:urea

答案:uricacidWhichoneofthefollowingdoesnotoccursinthedegradationpathwayofAMP?（）

A:AdenosineisconvertedtoadenineB:AdenineisconvertedtohypoxanthineC:TheendproductisCOD:AMPisconvertedtoadenosine

答案:TheendproductisCO

第十章單元測(cè)試

Allproductsofliverbiotransformationarenontoxic.（）

A:錯(cuò)B:對(duì)

答案:錯(cuò)Intheenterohepaticcirculationonlyalittlefractionofbileacidsarereabsorbedintheintestine.（）

A:錯(cuò)B:對(duì)

答案:錯(cuò)Whichofthefollowingreactionsisthemostcommonconjugationintheliver?（）

A:Conjugation

with

sulfateB:Conjugation

with

glutathioneC:Conjugation

with

glucuronic

acidD:Conjugation

with

acetate

答案:Conjugation

with

glucuronic

acidWhichofthefollowingreactionsisthemostcommonconjugationintheliver?（）

A:SAMB:PAPSC:UDPGD:UDPGA

答案:UDPGAWhichofthefollowingenzymeistherate-limitingenzymeintheprocessofbileacidssynthesis?（）

A:3α-dehydroxylationB:7α-hydroxylationC:7α-dehydroxylationD:3α-hydroxylation

答案:7α-hydroxylation

第十一章單元測(cè)試

Thebilirubinissparinglysolubleinplasmaandwater.（）

A:錯(cuò)B:對(duì)

答案:對(duì)Unconjugatedbilirubincanbesecretedintotheurineinourbodies.（）

A:錯(cuò)B:對(duì)

答案:錯(cuò)Whatdothedailybilirubinformationderivemainlyfrom?（）

A:cytochromeB:bilinC:myoglobinD:hemoglobin

答案:hemoglobinWhat‘sthematerialsofhemesynthesis?（）

A:arginine,succinylCoA,Fe2+B:glycine,succinylCoA,Fe2+C:glycine,acetyl-CoA,Fe2+D:glycine,acetyl-CoA,Cu2+

答案:glycine,succinylCoA,Fe2+Howmanyoxygenscanamoleculeofhemoglobinbind?（）

A:4B:3C:2D:1

答案:4

第十二章單元測(cè)試

ThesequenceofoneDNAstrandisATGCAA,thecomplementarystrandofDNAis（）

A:ATGCAAB:TACGTTC:UUGCAUD:TTGCATE:UAGCAA

答案:TTGCATTheenzymeinchargeofproofreadingfunctioninDNAreplicationis（）

A:PrimaseB:HelicaseC:DNAligaseD:DNApolymeraseE:Topoisomerase

答案:DNApolymeraseInthereplicationofeukaryoticDNA,（）

A:anewDNAstrandisalwayssynthesizedinthe3’5’direction.B:thetemplateisreadinthe5’3’direction.C:theleadingstrandissynthesizedinthedirectiontakenbythereplicationfork.D:thelaggingstrandissynthesizedinthedirectiontakenbythereplicationfork.E:bothleadingstrandandlaggingstrandaresynthesizedinadirectionoppositetothatinwhichthereplicationforkmoves.

答案:theleadingstrandissynthesizedinthedirectiontakenbythereplicationfork.Whatisthefunctionofthe3'to5'exonucleaseactivityofbacterialDNApolymerases?（）

A:processesprecursorsofribosomalRNAB:removesmismatchedbasesduringreplicationC:initiatesmRNAsynthesisD:removestheRNAprimersofOkazakifragments

答案:removesmismatchedbasesduringreplicationAllofthefollowingstatementsconcerningDNAreplicationinprokaryotesaretrueEXCEPT____?（）

A:Replicationisbidirectionalfromasingleinitiationpoint.B:UnwindingofthedoublehelixrequiresATPhydrolysis.C:Replicationoccursina5'to3'direction.D:OkazakifragmentsarejoinedbyDNApolymeraseIII.

答案:OkazakifragmentsarejoinedbyDNApolymeraseIII.DNApolymeraseIIIcanonlyaddnucleotidestoanexistingchain,so_____isrequired.（）

A:helicaseB:anRNAprimerC:aDNAprimerD:DNApolymeraseI

答案:anRNAprimerXerodermapigmentosum(xp)resultsfromadeficiencyin_____.（）

A:DNArepairB:atumorsuppressorC:DNAreplicationD:collagensynthesis

答案:DNArepairRegardingtheprocessofDNAreplicationinE.coliwhichofthefollowingstatementsisWRONG?（）

A:Thereisauniquesiteatwhichreplicationisinitiated.B:ThemechanismofreplicationissuchthatthereisaleadingstrandandalaggingstrandateachreplicatingforkC:DNAreplicationisunidirectional.D:DNAreplicationisasemiconservativeprocess.

答案:DNAreplicationisunidirectional.DNApolymeraseIdonothas_____.（）

A:HelicaseactivityB:3’→5’exonucleaseactivity.C:5’→3’exonucleaseactivity.D:polymeraseactivity.

答案:HelicaseactivityOkazakifragmentsare_____.（）

A:synthesizedinthe3'to5'direction.B:foundonthelaggingstrand.C:foundontheleadingstrand.D:assembledascontinuousreplication.

答案:foundonthelaggingstrand.

第十三章單元測(cè)試

ThetemplatestrandofDNAis5’-ATTCAG-3’,itstranscriptis（）

A:5’-TAAGTC-3’B:5’-CUGAAU-3’C:5’-GACTTA-3’D:5’-UAAGUC-3’E:5’-CTGAAT-3’

答案:5’-CUGAAU-3’WhichofthefollowingisNOTtrueoftheprokaryotic(E.coli)transcriptionalprocess?（）

A:specificsequencesinthepromoterarenecessaryforstablebindingofRNApolymerase.B:terminationrequiresspecialsequences(signals)inthenascentRNAchain.C:AseparatehelicaseenzymeisnecessaryforunwindingtheDNAtemplatetocreateanopencomplex.D:sigmafactorisrequiredonlyduringtheinitiationprocess.

答案:AseparatehelicaseenzymeisnecessaryforunwindingtheDNAtemplatetocreateanopencomplex.TheTATAboxineukaryotesisa_____.（）

A:-10sequence.B:-35sequence.C:corepromoter.D:5'cap.

答案:corepromoter.Whichofthefollowingstatementsiscorrectaboutprokaryoticgeneexpression?（）

A:Allofthesestatementsarecorrect.B:ProkaryoticmRNAsmusthaveintronssplicedout.C:ProkaryoticmRNAsareoftentranslatedbeforetranscriptioniscomplete.D:ProkaryoticmRNAscontainthetranscriptofonlyonegene.

答案:ProkaryoticmRNAsareoftentranslatedbeforetranscriptioniscomplete.IndicatewhichofthefollowingeventscanoccurduringtheprocessingofeukaryoticmRNAtranscripts.（）

A:MethylationofallGresidues.B:Splicingtogetherofexons.C:Excisionsofintrons.D:Attachmentofapoly(A)tailtothe5’endofthetranscript.

答案:Excisionsofintrons.TheAAUAAAsequenceonaRNAmoleculemarks_____.（）

A:Thesitenearwhichtheprimarytranscriptiscleavedandapoly(A)sequenceisadded.B:Thesitewheretranscriptionstops.C:Thesitewherethereleasefactorwillbindtoendpolypeptidesynthesis.D:Thesitewhereribosomesbindtoinitiatepolypeptidesynthesis.

答案:Thesitenearwhichtheprimarytranscriptiscleavedandapoly(A)sequenceisadded.RNApolymeraseisboundinitiallyto_____ofanoperon?（）

A:structuralgenesB:PromoterC:OperatorD:enhancer

答案:PromoterPost-translationalmodificationsofpolypeptidesincludeallthefollowingEXCEPT_____?（）

A:removalofmethionineB:proteasecleavageC:cappingby7-methylguanidineD:disulfidebondformation

答案:cappingby7-methylguanidine

第十四章單元測(cè)試

Thedirectionofproteinsynthesis(polypeptidechain)is（）

A:NoneofaboveB:FromCtoNC:FromNtoCD:From3’to5’E:From5’to3’

答案:FromNtoCThesequenceofnucleotideofinitiationcodenis（）

A:UAAB:UAGC:UGAD:AGUE:AUG

答案:AUGIfthecodenofmRNAisACG,thenthean