注：不含主觀題第1題單選題(1分)1.Cancershavingvariousoriginandbiologicalbehaviorproducemultiplesymptoms.Whatis

thebasisofmultiplesystoms?AThesizeoftumorBthespreadoftumorCTheshapeoftumorDthelocationoftumor第2題單選題(1分)2.whichofthefollowingcanbeusedtoevaluatecancerpatientstatus?AKPSBNRSCkillipDChild第3題單選題(1分)3.whatareriskfactorsofmanycommoncancers?AgeneticpredispositionBfamilyhistoryCTobaccoandalcoholDcausepotentialexposure.第4題單選題(1分)4.whatisthemeaningofMinTNM?AmechanismBmetastasisCmethodDmodel第5題單選題(1分)5.whichofthefollowingareusedtostagediseaseandassessthetumorresponsetotreatment?AhistorytakingBtheprimarytumorCheregionallymphnodesDclinicalexamination第6題單選題(1分)6.whatisthecommontumormarkerusedinovarian?ACEABCA199CCA125DCA724第7題單選題(1分)7.Whichexaminationissuperiorin

defining

anatomy

and

vascular

structures

within

soft

tissue?ACTBMRI.CXRayDultrasound第8題單選題(1分)8.whatexaminationisusedtodiagnosecancer?ACTBPET/TCpathologyDbloodtest第9題單選題(1分)9.

Bonescansare

highly

sensitive

butlessspecific

–

inflammation,

infection

and

a

healing

fracture

mayall

produce

a

hotspot

similar

to

a

single

metastatic

lesion.Whenabnormalimagesweredetected,()

may

provide

a

diagnosis

in

this

setting.ACTBMRICXRayDultrasound第10題單選題(1分)Inbreastcancer,()usuallyabnormallyincreases.ACA15-3BCA199CCA125DCA724第11題多選題(2分)1.whataspectsshouldbedepicted,iftheprimarytumorisreadilytoinspectandpalpate.AsizeBsiteCshapeDconsistencyEmobility正確答案：ABCDE第12題多選題(2分)2.Aidealtumormarkerwouldhavethefollowingcharacteristics:AhighspecificB

producedinproportiontothebulkofthedisease,

CcheapDwidelyavailableEdetectedinmanycancers正確答案：ABCD第13題多選題(2分)3.Historytakingcanbebasedontheseaspects:Atheprimarytumor.Binvolvedlymphnodes.Cdistantmetastases.DparaneoplasticsyndromesEcomplaints正確答案：ABCD第14題多選題(2分)4.whataspectsshouldbedepictedindetail

duringhistorytaking?Apreviousmedicalhistory.Bsurgicalhistory.Cfamilyhistory.DsocialhistoryEpresentcomplaints.正確答案：ABCDE第15題多選題(2分)5.

whichlocationdiagnosisandassessmentfrequentlyusedUltrasoundincancerpatients?AboneBbreastCbrainDliverElymphnodes.正確答案：BDEInvestigations第1題單選題(1分)Comparingwithclinicaloncologist,whatdoepidemiologistscaremoreabouttumors?APsychologicalstatusofcancerpatientsBTheeconomicburdenofcancerCThepathologicalcharacteristicsoftumorsandtheirexaminationresultsDThedegreetowhichcancerpatientsrelyonpainkillersEThecausesoftumorsandthefactorsaffectingtheirtreatmentandprognosis正確答案：E第2題單選題(1分)Whichofthefollowingisnotacommonmethodforbiopsytechniques?AMagneticResonanceImaging(MRI).BFineneedleaspirationbiopsy(FNAB).CCoreneedlebiopsy.DExcisionbiopsy.EFrozensection.第3題單選題(1分)Whichofthefollowingisnotacommonmethodforradiologicalinvestigations?APlainX-rayBUltrasoundCRadiotherapyDComputedtomography(CT)ERadionuclideimaging第4題單選題(1分)Ifyouwanttostudythesideeffectsofanewcancerdrug,whichof

thefollowingstudiesisbetter?ACase-controlstudy.BCorrelationalstudy.CPrevalencestudy.DNestedcase-controlstudy.ECohortstudy.第5題多選題(2分)

Whatmightcancerpatientsneedtobecheckedatdifferentstagesoftreatment?AThestagesofdiseaseBAssessmentofresponsetotreatment.CFollow-upaftertreatment.DAssessmentoforganfunctionpriortotreatment.EManagementoftreatmentcomplications.正確答案：ABCDE第6題多選題(2分)Whichchoicesarethecharacteristicsoftumormarkers？AItusuallyroseinthepresenceofearlystagedisease,whichallowingearlydiagnosisandtreatment.BItisspecific,beingraisedonlyinthepresenceofthemalignancy,notinanybenignconditions.CIt

maybe

producedinproportiontothebulkofdisease.DItshouldbethegoldstandardforcancerdiagnosis.EItischeapandwidelyused正確答案：ABCEStagingandSurvivalStatistics第1題單選題(1分)Whatdoes“M”referstoinTNMstagingsystem?AThesizeandextentofthemaintumor.BThedegreeofmalignancyofthetumor.CThenumberofnearbylymphnodesthathavecancer.DWhetherthecancerhasmetastasized.EWhetherthecancerhasrecurred.

第2題單選題(1分)What’sthewrongdescriptionofTNMgrades?AN1-3referstothenumberandlocationoflymphnodesthatcontaincancer.ThelowerthenumberaftertheN,themorelymphnodesthatcontaincancer.BNXindicatescancerinnearbylymphnodescannotbemeasured.CT0indicatesmaintumorcannotbefound.DM0indicatestumorhasnotspreadtootherpartsofthebody.EM1referstodistantmetastasis(Thatmeanstumorhasspreadtootherpartsofthebody).

第3題單選題(1分)WhichofthefollowingcancerscannotbestagedusingtheTNMsystem?ABreastcancer.BBloodcancer.CColorectalcancer.DNon-small-celllungcarcinoma.ECerebroma.

第4題單選題(1分)Whichofthefollowingisnottheindicatorofsurvivaltime?ASurvivalrate.BDisease-freesurvival.CProtectiverate.DOverallsurvival.EMediansurvival.

第5題單選題(1分)Whichofthefollowingmethodsismostcommonlyusedforregression

analysisofmultiplecovariables?AKaplan-Meiermethod.BBreslowtest.CLog-ranktest.DChi-SquareTest.ECoxProportionalHazardsmodel.

正確答案：E第6題單選題(1分)Whatisthemostcommonworkweneedtodointhesurvivalanalysisofcancerpatients?ASurvivalratesestimationandcomparison.BObversecancerpatients.CHandlemissingvalues.DMakechartstoillustratetheresults.EDefineendpointevent.

第7題多選題(2分)Whatarethethreeelementsofsurvivaltime?AObservationstartingpoint.BCancertypes.CEndingevent.DAgeofpatients.ETimemeasurementunit.正確答案：ACE第8題多選題(2分)Whichofthefollowingmethodsisusedtoanalyzesurvivaldata?ALifetablemethod.BKaplan-Meiermethod.CLog-ranktest.DBreslowtest.ETtest正確答案：ABCDChemotherapy第1題單選題(1分)Accordingtothehypnoticcycledynamics,thechemotherapydrugsaredividedinto:ACellcyclespecificdrugsandcellcyclenon-specificdrugsBTraditionalChinesemedicineandWesternmedicineCEndocrinedrugsandmolecularlytargetedtherapydrugsDChemotherapydrugsthatactoncancercellsandpericycouscells第2題單選題(1分)Smallcelllungcancerhasmultiplebonemetastases,whichtreatmentoptionisthebestASystemicchemotherapyBRadiationtherapyatthebonelesionCSystemicchemotherapy+BisphosphatetherapyDBisphosphatetherapy第3題單選題(1分)Duringchemotherapyorradiationtherapy,themostimportantobservationitemsforcancerpatientsare:ADegreeofhairlossBLossofappetiteCSkinlesionsDWhitebloodcellandplateletcounts第4題單選題(1分)Neoadjuvantchemotherapyis:AChemotherapyadministeredaftersurgeryorradiationBChemotherapyadministeredbeforesurgeryorradiationCCancertreatmentwhereonlychemotherapyisadministeredDCancertherapywherechemotherapyisnotadministered第5題單選題(1分)Whatisthemostlikelycauseoffrequentbleedingandbruisingwhenapersonisreceiving

chemotherapy?AAnemia–lowredbloodcellcountsBNeutropenia–lowwhitebloodcellcountsCThrombocytopenia–lowplateletcountsDInflammationofthemucousmembranes第6題單選題(1分)Whichofthefollowingexplainsthehairlossoftenassociatedwithchemotherapy?AChemotherapyworksbydestroyingthefastest-growingcellsBChemotherapystimulatesthegenesthatcausebaldnessCHairlossonlyoccurswhenchemotherapyisgivenintravenouslyDHairlossoccurswhenchemotherapyisgivenforheadandneckcancers第7題單選題(1分)Whatgivespeoplethebestpossiblechanceofsurvival?AChemotherapyBcancerscreeningsChealthylifestylechoicesDearlydiagnosis第8題單選題(1分)Thefollowingantineoplasticdrugshaveahighriskofvomiting:AEtoposideBCisplatinCMethotrexateDgemcitabine第9題單選題(1分)ThecurrentpreferredchemotherapyregimenforHLisAMOPPBCHOPCABVDDCOP第10題單選題(1分)ThemostcriticalofthephasedevaluationindicatorsofchemotherapyefficacyisASymptomsarerelievedBThetumorshrinksCChangesintumormarkersDProlongedsurvival第11題多選題(2分)Thoseofthefollowingarecontraindicationstochemotherapy：ABonemarrowreservefunctionislow,withpre-treatmentwhitebloodcellbelow3.5x10^9/Landplateletsbelow80x10^9/LBSevereinfection,highfeverCGastrointestinalobstructionDSuperiorvenacavasynthesis正確答案：ABC第12題多選題(2分)Whichofthefollowingtumorsaresuitableforpostoperativechemotherapy：AbreastcancerBColoncancerCNon-smallcelllungcancerDLeiomyosarcoma正確答案：ABC第13題多選題(2分)Whataretheadverseeffectsoflong-termuseofchemotherapydrugs？AGastrointestinalreactionsBInhibitshematopoieticfunctionCHairloss,nephrotoxicityDPeripheralneuritis正確答案：ABCD第14題多選題(2分)Whatarethemodalitiesofchemotherapyfortumors？ARadicalchemotherapyBAdjuvantchemotherapyCNeoadjuvantchemotherapyDPalliativechemotherapy正確答案：ABCD第15題多選題(2分)Vomitingcausedbychemotherapycanbedividedinto(accordingtothetimeofoccurrenceAAcutevomitingBDelayedvomitingCExpectedvomitingDChronicvomiting正確答案：ABCRadiationTherapyExaminationPapers第1題單選題(1分)Radiotherapyuseshighenergyradiationtokilltumorcellsbydamagingtheir

（）ADNABRNACMitochondrionDEndoplasmicreticulum第2題單選題(1分)Whichkindofdamage

is

thought

to

be

thecruciallesioncaused

by

ionising

radiation？APointmutationBThedouble

strand

breakCThe

single

strand

breakDTransposition第3題單選題(1分)Theradiotherapyshowninthefigureiscalled（）AIntracavitaryBInterstitialCSurfacemouldDLinearaccelerators第4題單選題(1分)Whichofthefollowingtissuesisanearlyresponsetissuetoradiation？（）ACardiovascularBKidneyCNervoussystemDSkin第5題單選題(1分)Whichofthefollowingiswrongabout

linear

accelerator？（

）AItis

costly

to

buyandmaintain.

BThe

radiotherapydeliveredbyalinearacceleratorisgivenfromoutsidethepatient.CA

linear

accelerator

emits

X

raysthrougharadiationsource.DIt

generates

a

beam

ofionising

radiation

by

firingelectronsat

a

target.第6題單選題(1分)Whatkindofradiationdoesa

cobaltmachineemits？（

）A

γ

radiationBα

radiationCβ

radiationDX-rayradiation第7題單選題(1分)Whatisthedoseofradicalirradiationforheadandneckcancer？A40-50GyB50-54GyC50-60GyD60-70Gy第8題單選題(1分)Whatisthedoseofpostoperativeradiotherapyforbreastcancer？A40GyB50GyC60GyD70Gy第9題單選題(1分)AhigherdoseperfractionisusuallyusedforA

HeadandNeckCancerBBreastCancerCKidneyCancerDBone

metastases第10題單選題(1分)Conventional

radicalradiotherapy

isdeliveredat

（

）

Gyperfractionwithonefractiongivenperday.A1.2B2C5D8第11題多選題(2分)Altered

fractionation

schemes

includethefollowing

（

）AHypofractionation

radiotherapyB

Hyperfractionation

radiotherapyCAcceleration

radiotherapyDconventional

radical

radiotherapy正確答案：ABC第12題多選題(2分)Whichofthefollowingarecommonradiotherapyplanning？（

）A2D

planningB3DCRTC

4D

planningDIMRT正確答案：ABD第13題多選題(2分)Whateffectcanradiotherapyplayontumors？（

）AImprove

local

controlBImprove

overall

survivalCImprove

median

survivalDRelievesymptoms正確答案：ABCD第14題多選題(2分)Whichofthefollowing

are

earlyresponsetissues

toradiation？（）AKidneyBMucosaCSkinDTumor正確答案：BCD第15題多選題(2分)Whichofthefollowing

are

main

advantages

of

high

energy

linear

accelerators？

（

）ASkin

sparingBGreaterbeam

penetration

producinghigher

radiation

doses

at

greaterdepth.CSophisticated

planning

techniquescanbe

used

incorporating

multiplebeams

from

different

directionscalculated

to

deliver

therequireddoseto

thetarget

area.DThere

is

a

sharp

fall-off

in

doselevelat

theedgeof

thebeam.正確答案：ABCDTargetedtherapy第1題單選題(1分)Whatarethefactorsthatneedtobeconsideredindevelopingpersonalizedanti-tumortreatmentregimens?AAge,sex,andraceofthepatientBPathologicaltypes,stages,tolerancesandmolecularbiologicalcharacteristicsofthetumorsCPersonalintentiontotreatDAlloftheabove

第2題單選題(1分)TheCETUXIMABapplies?AMetastaticcoloncancerwithRasGeneMutationBMetastaticcoloncancerwithwild-typeRASGeneCMetastaticgastriccancerwithRasGenemutationDMetastaticgastriccancerwithwild-typeRASGene第3題單選題(1分)Whichofthefollowingdrugsisatyrosinekinaseinhibitor?AInterferonBBortezomibCTamoxifenDErlotinib第4題單選題(1分)What’sthewrongoptionaboutthebevacizumab?AApprovedforthetreatmentofmetastaticcolorectalcancer.BItcanbeusedforadvanced,metastaticorrecurrentnon-smallcelllungcancer.CNogenetictestingrequired.DItcanonlybeusedaftergenetictesting.第5題單選題(1分)ThetargeteddrugsmainlyusedinpatientswithnonHodgkin'slymphomais?ATrastuzumabBBevacizumabCRituximabDCetuximab第6題單選題(1分)Patientseligiblefortrastuzumabare?AHER-2(-)breastcancerBHER-2(+)breastcancerCHER-2(-)gastriccancerDgastriccancerwithwild-typeEGFRGene第7題單選題(1分)Indicationsforimatinibmesylate?APhiladelphiachromosomepositivechronicmyeloidleukemiaBMetastaticcoloncancerCnon-smallcelllungcancerDMetastaticbreastcancer

第8題單選題(1分)Targetedtherapyworksbytargeting(

)thatcontributestocancergrowthandsurvivalAthecancer’sspecificgenesBthecancer’sspecificproteinsCthetissueenvironmentDAlloftheabove

第9題單選題(1分)WhichofthefollowingisnotaEGFR-TKIdrug?AgefitinibBerlotinibCafatinibDRituximab

第10題單選題(1分)Theclassificationoftargeteddrugsdoesnotincluded?AtargetedsmallmoleculesBantibodiesCcancervaccinesDchemokine第11題多選題(2分)Themechanismsoftargetedmoleculardrugsinclude?AActingoncellmembrane,targetingtransmembranegrowthfactorreceptorpruritus

BDrugsactingoncytoplasmtargetintracellularsignaltransductionprocesses

CDrugsthatactonthenucleustargetDNAorRNADActingontheextracellularenvironmentofcancercells正確答案：ABCD第12題多選題(2分)Themainadversereactionsofmoleculartargetedantitumordrugsinclude?A

Skintoxicity:skinrash,handfootskinreactionorsyndrome,etc.BAdversereactionsofdigestivesystem:diarrhea,nausea,vomiting,lossofappetite,etc.CCardiovasculartoxicity:hypertension,decreasedleftventricularejectionfraction(LVEF),myocardialischemia/infarction,prolongedQTinterval,etcDEdema,waterandsodiumretention,oralmucositis正確答案：ABCD第13題多選題(2分)Accordingtotheclassificationofdrugstructure,themostcommonanti-tumormoleculartargeteddrugsinclinicaresmallmoleculetargeteddrugsandmonoclonalantibodydrugs？A

smallmoleculetargeteddrugsBcytokineCmonoclonalantibodydrugsDantibiotic正確答案：AC第14題多選題(2分)14.WhichfollowingstatementistrueaboutHodgkin'slymphoma?AALKpositiverecurrent/refractorysystemicanaplasticlargecelllymphomaBsmallcelllungcancerC

Hodgkinlymphoma.DALKpositivepatientswithlocallyadvancedormetastaticnon-smallcelllungcancer

正確答案：AD第15題多選題(2分)whichofthefollowingdrugsisisbelongingtotheantibodydrugs?ATrastuzumabBBevacizumabCRituximabDCetuximab正確答案：ABCDsurgicaloncology第1題單選題(1分)Duringroutinephysicalexamination,a45-year-oldwomanwasfoundtohavepalpableapainlessmassmeasuringabout3.8cmindiameterinherrightbreast.Themasswasfixedwithpooractivity.Anotherpainlessmassofabout2cmwaspalpableundertheleftaxilla.Chestradiographshowedmultiple0.5-2cmnodulesinbothlungs.Whichofthefollowingcategoriesbestindicatesthestageofherillness?A

T1N1M0

BT2N1M0

C

T1N0M1

D

T3N0M0

ET4N1M1正確答案：E第2題單選題(1分)A60-year-oldmanpresentedwithweightlossandfatigueandfounda3cmmassintheupperpartofhisleftlung.Aneedlebiopsyofthemasswasperformedandmicroscopicexaminationrevealedanirregularinfiltrateofanaplasticcellswithnumerousmitoses,manyofwhichwereatypicalinappearance.Sincethetumorwasconfinedtothelung,furtherstudiesfailedtorevealthepresenceofanymetastaticdisease.Whatisthebestclassificationforthistumorwithlimitedinformation?AABBCCDDEE第3題單選題(1分)Whichoneoffollowingnumberedsequencesbestillustratesthepostulatedsequencesofeventsthatprecedestheformationofaninfiltratingsquamouscellcarcinomaofthecervix?1=carcinomainsitu2=invasivecarcinoma

3=Milddysplasia4=moderatedysplasia5=severdyspalsia6=squamousmetaplasiaA345162B345612C543162D634512E643521第4題單選題(1分)A44-year-oldwomannotesamassinherleftbreastwhiletakingashower.Herphysicianpalpatesa3cmfirm,irregular,non-movablemassintheupperouterquadrantofherleftbreastonphysicalexamination.Afineneedleaspirationofthismassisperformed,andthecellsobtainedareexaminedcytologicallyandareconsistentwithinfiltratingductalcarcinoma.Themassisremovedwithlumpectomyalongwithanaxillarylymphnodedissection.Whichofthefollowingfindingswillbestpredictabetterprognosisforthispatient?

AFlowcytometricanalysiswithaneuploidyandahighS-phase

BTumorcellsstronglyestrogenreceptorpositive

CNometastasesinthesampledlymphnodes

D

Onerelativewhohadasimilartypeofbreastcancer

EHightumorgrade第5題單選題(1分)Duringroutinephysicalexamination,a16-year-oldhealthygirlwasfoundtohavea0.4cmreddish,slightlyelevatednoduleontheupperskinofherchest.Thecomplaintwasthatthislesionhadbeenpresentformanyyearswithoutsignificantchangesinsizeandcolor.Whichofthefollowingtumorsisthisnodulemostlikelytobe?A

Carcinoma

BLymphoma

CMelanoma

D

Hemangioma

E

Glioma

第6題單選題(1分)Thepatient,a60-year-oldmanwithahistoryofsmoking,hadchroniccoughinthepast10years.Inthepastyear,helostabout4kilogramsinweight.Thephysicalexaminationresultsshowednoabnormality.HischestX-rayshowedamassintherighthilum.Cytologicalexaminationofsputumshowedatypicaland

hyperchromaticsquamouscells.Whatisthemostcommoninitialpathwayofthislesionmetastasis?A

Pleuralcavity

BBloodstreamCBronchiDLymphatics

EContiguousspreadtochestwall

第7題單選題(1分)A56-year-oldmandiedafterayear-longillness.Autopsyreportshowedmultipletumormassesabout2to5cminsizeinhisliver.Theyweretanandhard,generallywithcentralnecrosisandcarcinomatousumbilicusappearance.Thesurroundingliverparenchymawasnormal.Whichofthefollowingfeaturesofneoplasiaarebestcharacterizedbythesefindings?A

Multicentricorigin

BHightumorgrade

CPrimaryneoplasminthestomachDExposuretoacarcinogen

E

Advancedstage第8題單選題(1分)A48year-oldwomannotesamassinherleftbreast.Shegoestoherphysician'sassistant,whopalpatesa2cmfirmmassinherleftbreast.Afineneedleaspirationbiopsyisperformed,andonmicroscopicexaminationaductalcarcinomaisseen.Apoorerprognosisforthepatientismostcloselyassociatedwithwhichofthefollowingfindings?AAneuploidybyflowcytometry

BPositiveimmunohistochemicalstainingforestrogenreceptor

CWell-differentiatedhistologicappearance

DIntraductalgrowthpatternEStageofT1N0M0第9題單選題(1分)A48-year-oldwomanhasnotedamassonherleftshoulderthathasenlargedoverthepast6months.Onphysicalexaminationthereisanenlarged,non-tendersupraclavicularlymphnode.Abiopsyofthenodeisperformedandonmicroscopicexaminationthereisametastaticneoplasm.Whichofthefollowingisthemostlikelyprimaryneoplasm?

ACerebralglioma

BAdenocarcinomaofthestomach

CFibroadenomaofthebreast

DLiposarcomaoftheretroperitoneum

ELaryngealpapilloma第10題單選題(1分)Epidemiologicalstudieswereusedtoidentifyriskfactorsformalignancy.Statisticalanalysiswasperformedonthepre-existingconditions.Somepreexistingconditionswereobservedtoprecedethedevelopmentofmalignancy,whileotherswerenot.Whichofthefollowingconditionsismostlikelytobestatisticallyunrelatedtomalignancy?AEndometrialatypicalhyperplasiaBChronicalcoholismwithhepaticcirrhosisCCervicalsquamousdysplasia

DChroniculcerativecolitis

EUterineleiomyomas正確答案：EBreastCancer第1題單選題(1分)Whichofthefollowingisthemostcommontypeofbreastcancer?AIntraductalcarcinomainsituBInvasiveductalcarcinomaCInvasivelobularcarcinomaDLobularcarcinomainsitu第2題單選題(1分)What'sthemeaningofStage0breastcancer?ABreastfibroadenomaBInflammatorybreastcancerCNoninvasiveorcontainedwithinthemilkductsDMetastaticbreastcancer第3題單選題(1分)Whatcanwedotoreducetheincidenceofbreastcancer?AExercisemostdaysoftheweekBDrinkatwillCReceivepostmenopausalhormonetherapy.DEattoomuchfriedfood第4題單選題(1分)WhichStagedoesitbelongto,if

breastcancerhasspreadtotheliver?AIBIICIIIDIV第5題單選題(1分)Inyouropinion,whichistheoptimaltreatmentmethod,ifbreastcancerhasalreadyspreadtootherpartsofthebody?AChemotherapyBPalliativecareCOperateassoonaspossibleDRadiationtherapy第6題單選題(1分)Whichsubtypeofbreastcancerismostlikelytobenefitfromtargetedtherapy?ALuminalBTriple-negativeCHer-2DAllabove第7題單選題(1分)Whatdoesitmeanifthedoctoraskapatientforabiopsy?ATakingapictureofthebreastBRemovingasampleofbreastcellsfortestingCGettingabreastmagneticresonanceimagingDReceivingemergencysurgicaltreatment第8題單選題(1分)Whatmaydoctorsrecommendafteramastectomyfor

cancersthathavespreadtothelymphnodes?ABreastbrachytherapyBTakingtargeteddrugsCRadiationtherapytothechestwallDNoneofthem第9題單選題(1分)Whatkindoftreatmentwouldbenefitthepatientswithtriple-negativebreastcancer?AImmunotherapyBTargetedtherapyCHormonetherapyDPalliationtherapy第10題單選題(1分)Whataretheadvantageoftargeteddrugsoverchemotherapeuticagents?ALowerpriceandbettertasteBBlockinghormonesfromattachingtocancercellsCDamagingcancercellswhilesparinghealthycellsDImprovingcardiacfunctionofcancerpatients第11題多選題(2分)

Accordingtothecontentof

courses,whichoptionsare

thebasisformolecularsubtypeofbreastcancer？AERBPRCKi-67DHer-2正確答案：ABCD第12題多選題(2分)Whatfactorsmaybe

relatedwithanincreasedriskofbreastcancer?A

BeingmaleBRadiationexposureC

Havingneverbeenpregnant.DBeginningherperiodattheageof10正確答案：BCD第13題多選題(2分)Whatkindsofmedications

canbeincludedinhormonetherapy?A

AromataseinhibitorsB

Targeteddrugs,suchas:TrastuzumabC

SelectiveestrogenreceptormodulatorsD

Ovarianfunctionsuppression正確答案：ACD第14題多選題(2分)

Whatdiseaseswillpeoplebemorelikelytosufferfrom,ifthereissignificantamplificationofBRCA1andBRCA2?A

LungcancerBBreastcancerCOvariancancerD

Livercancer正確答案：BC第15題多選題(2分)

Whichsymptomcouldappearinbreastcancer?AAnewlyinvertednipple.BChangestotheskinoverthebreast,suchasdimpling.C

AlumpintheatupperlateralquadrantofthebreastDSize,shapeorappearancechangeofbreast.正確答案：ABCDCarcinomainsituandearlybreastcancer第1題單選題(1分)Malebreastcancersaccountfor(

)ofallbreastcancers.A0.1%B1%C2%D5%第2題單選題(1分)Whichofthefollowinglesionsisamalignantdisease?(

)ADuctalcarcinomainsituBLobularcarcinomainsituCFibrosarcomaDIntraductalpapillomas第3題單選題(1分)(

)isnotprecancerouslesions.AFlatepithelialatypiaBAtypicalductalhyperplasiaCIntraepitheliallesionDUsualductalhyperplasia第4題單選題(1分)(

)hasthelowestmitoticrate.ALowgradeDCISBIntermediategradeDCISCHighgradeDCISDInvasivebreastcarcinoma第5題單選題(1分)Indiagnosticmammograph,(

)isaperformancebenchmarkofDCISALumpBPopcorncalcificationCAmorphouscalcificationDCalcificationswithrailroadtrackpattern第6題單選題(1分)(

)istheprimarytreatmentofductalcarcinomainsitu.AEndocrinetherapyBSurgeryCChemotherapyDRadiotherapy第7題單選題(1分)(

)istheonlyscreeningmethodthatcanreducethemortalityofbreastcancer.

AUltrasoundBCTCMRIDMammogram第8題單選題(1分)SurgicalmarginsinbreastconservingsurgeryperformedonDCISpatientsshouldbe(

)atleast.A1mmB2mmC5mmDNoinkontumor第9題單選題(1分)Endocrinetherapy,usuallyusing(

),canreducetherecurrencerateofbreastcancerbilateral.ALetrozoleBFulvestrantCTamoxifenDExemestane第10題單選題(1分)(

)isessentialinthetreatmentofHER-2positivebreastcancerpatients.ATrastuzumabBAnthracyclineCPaclitaxelDPlatinum

第11題多選題(2分)

Whichofthefollowingsingsmayindicatebreastcancer?()A

AbreastlumpBBreastpainCBloodynippledischargeDDumplingofbreastskin正確答案：ACD第12題多選題(2分)Thetreatmentofductalcarcinomainsituincludes()AEndocrinetherapyB

SurgeryCChemotherapyDRadiotherapy正確答案：ABD第13題多選題(2分)Usingtamoxifeninlongtermmaycause().ANumbnessBEndometrialcancerCThromboemboliceventsDFracture正確答案：BC第14題多選題(2分)Optionsforsurgicalmanagementoftheprimarybreasttumorinclude().A

LumpectomyaloneBBreastconservingsurgeryC

MastectomyD

Mastectomyplusreconstruction正確答案：BCD第15題多選題(2分)Whichofthefollowingregimentsareusinginthetreatmentofbreastcancer.

A

TrastuzumabB

AnthracyclineC

PaclitaxelDPlatinum正確答案：ABCDLocallyadvancedbreastcancer(LABC)andinflammatorybreastcancer(IBC)第1題單選題(1分)Theinitialstepinevaluatingthepatient?ABilateralmammographyBRadionuclidebonescanCChestCTDExaminationoftheskin,breastsandlocoregionallymphnodesEUltrasoundoftheupperabdomenAnswer:D第2題單選題(1分)Inpatientswithtriple-negativebreastcancertheadditionof()tothetaxaneportionofastandardsequentialanthracycline/taxaneregimenimprovedresponseintherandomizedclinicaltrialCALGB40603?ADoxorubicinBCyclophosphamideCDocetaxelDCarboplatinEHerceptinAnswer:D第3題單選題(1分)TheriskofdeathfromIBCwasnearly()thatfromLABCaftermultivariateadjustmentforrace,age,tumorsize,axillarylymphnodalstatus,grade,andERexpression?AHalfBTwiceCTripleDQuintuple

第4題單選題(1分)ThemedianPFSoftheCEFpatientsintheNCCNGuidelinesforLABC/IBCwasA33.7monthsB34monthsC

51monthsD

53months第5題單選題(1分)What’sthewrongoptionaboutthe

SWOG0012?AComparisonofStandardDoxorubicinandCyclophosphamideVersusWeeklyDoxorubicinandDailyOralCyclophosphamidePlusG-CSFAsNeoadjuvantTherapyforInflammatoryandLocallyAdvancedBreastCancer.BNosignificanteffectoftreatmentonDFSinIBCorLABC.CHigherpCRrateswereobservedinthecontinuousarmversusthestandardarm.DTherewasnoevidencethatOSdifferedbytreatment.Answer:C第6題單選題(1分)TheGeparQuintostudycomparedtheefficacy(pCRrate)andsafetyofneoadjuvanttherapywithherceptinor()incombinationwithepirubicin+cyclophospamide()→docetaxel()inpati