Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEGOAT-IN-1Cat.No.:HY-103479CASNo.:1452473-54-9分?式:C??H??ClF?NO?S分?量:415.81作?靶點(diǎn):Acyltransferase作?通路:MetabolicEnzyme/Protease儲(chǔ)存?式:4°C,sealedstorage,awayfrommoisture*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoisture)溶解性數(shù)據(jù)體外實(shí)驗(yàn)DMSO:150mg/mL(360.74mM;ultrasonicandwarmingandheatto60°C)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM2.4049mL12.0247mL24.0494mL5mM0.4810mL2.4049mL4.8099mL10mM0.2405mL1.2025mL2.4049mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrommoisture)。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。BIOLOGICALACTIVITY?物活性GOAT-IN-1胃促?長(zhǎng)素O-酰轉(zhuǎn)移酶(GOAT)的抑制劑，可?于預(yù)防或研究肥胖、糖尿病、?脂?癥、?酒精性脂肝、脂性肝炎、?骼肌減少癥、?欲控制、精/?醉性依賴、阿爾茨海默癥、帕?森、腦?管疾病與?年癡呆、腦卒中、腦梗死、??管疾病、腫瘤等。體外研究TheinhibitoryactivityofGOAT-IN-1(Example16)forhumanGOATis101%withtheconcentrationof10μM[1].1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEREFERENCES[1].WO2013125732.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax