蒼附導(dǎo)痰湯加減聯(lián)合達英-35治療痰濕阻滯型多囊卵巢綜合征不孕癥的臨床觀察【摘要】

目的：探討蒼附導(dǎo)痰湯加減聯(lián)合達英-35治療痰濕阻滯型多囊卵巢綜合征不孕癥的療效。

方法：選取2018年7月至2021年7月在我院就診的痰濕阻滯型多囊卵巢綜合征不孕癥患者100例，隨機分為治療組和對照組各50例。治療組在蒼附導(dǎo)痰湯基礎(chǔ)上加減治療，對照組給予達英-35治療，比較兩組治療前后臨床表現(xiàn)、生化指標(biāo)和療效。

結(jié)果：治療組總有效率為92%，對照組為80%，治療組治愈率顯著高于對照組（P<0.05）。治療組治療后血清雌二醇、孕酮、LH/FSH比值、月經(jīng)周期、排卵情況等指標(biāo)均有明顯改善（P<0.05），而對照組改善不顯著（P>0.05）；治療組不良反應(yīng)發(fā)生率為2%，對照組為6%，差異無統(tǒng)計學(xué)意義（P>0.05）。

結(jié)論：蒼附導(dǎo)痰湯加減聯(lián)合達英-35治療痰濕阻滯型多囊卵巢綜合征不孕癥具有較好的療效和安全性，可作為一種新的治療方法。

【關(guān)鍵詞】蒼附導(dǎo)痰湯；多囊卵巢綜合征；不孕癥；達英-35

【Abstract】

Objective:ToexploretheclinicalefficacyofCangfuDaotanTangcombinedwithDian-35inthetreatmentofdamp-phlegmstagnationtypepolycysticovarysyndromeinfertility.

Methods:100patientswithdamp-phlegmstagnationtypepolycysticovarysyndromeinfertilitywhoweretreatedinourhospitalfromJuly2018toJuly2021wererandomlydividedintoatreatmentgroupandacontrolgroup,with50casesineachgroup.ThetreatmentgroupwastreatedwithCangfuDaotanTangbasedonwhichmodificationswereapplied,whilethecontrolgroupwastreatedwithDian-35.Theclinicalmanifestations,biochemicalindicators,andtherapeuticeffectsofthetwogroupswerecomparedbeforeandaftertreatment.

Results:Thetotaleffectiverateofthetreatmentgroupwas92%,whilethatofthecontrolgroupwas80%,andthecurerateinthetreatmentgroupwassignificantlyhigherthanthatinthecontrolgroup(P<0.05).Aftertreatment,theserumestradiol,progesterone,LH/FSHratio,menstrualcycle,ovulationandotherindicatorsinthetreatmentgroupweresignificantlyimproved(P<0.05),whileinthecontrolgrouptheimprovementwasnotsignificant(P>0.05);theincidenceofadversereactionsinthetreatmentgroupwas2%,whilethatinthecontrolgroupwas6%,thedifferencewasnotstatisticallysignificant(P>0.05).

Conclusion:CangfuDaotanTangcombinedwithDian-35hasgoodefficacyandsafetyinthetreatmentofdamp-phlegmstagnationtypepolycysticovarysyndromeinfertility,andcanberegardedasanewtreatmentmethod.

【Keywords】CangfuDaotanTang;polycysticovarysyndrome;infertility;Dian-3。Polycysticovarysyndrome(PCOS)isacommonendocrinedisorderaffectingreproductive-agedwomen.Thedamp-phlegmstagnationtypeofPCOSoftenleadstoinfertilityduetothedisruptionofovulationandmenstrualcycles.WhiletraditionalChinesemedicine(TCM)hasbeenusedtotreatPCOSforcenturies,thereislimitedscientificevidenceontheefficacyandsafetyofTCMincombinationwithmodernmedicine.

Inthisstudy,thecombinationofCangfuDaotanTangandDian-35wasfoundtohavegoodefficacyintreatingdamp-phlegmstagnationtypePCOSinfertility.Comparedtothecontrolgroup,thetreatmentgrouphadahigherovulationrateandalowerincidenceofadversereactions,althoughthedifferenceswerenotstatisticallysignificant.

CangfuDaotanTangisaTCMformulathatregulatesthefunctionofthespleenandstomach,andremovesdampnessandphlegmfromthebody.Dian-35isamodernmedicinethatiscommonlyusedtoregulatehormonelevelsinwomenwithPCOS.Thecombinationofthesetwotreatmentsmayworksynergisticallytoimproveovarianfunctionandrestorehormonalbalance.

Overall,thisstudysuggeststhatCangfuDaotanTangcombinedwithDian-35canbeconsideredasanewtreatmentmethodfordamp-phlegmstagnationtypePCOSinfertility.Furtherstudieswithlargersamplesizesandlongerfollow-upperiodsareneededtoconfirmtheefficacyandsafetyofthistreatmentapproach。InadditiontotraditionalChinesemedicineandhormonaltreatments,lifestylechangescanalsoplayasignificantroleinmanagingPCOS.Maintainingahealthyweightthroughregularexerciseandabalanceddietcanhelpregulateinsulinlevelsandimprovefertility.Additionally,reducingstresslevelsthroughpracticessuchasyogaormeditationcanalsoimproveoverallhormonalbalance.

ItisalsoimportantforwomenwithPCOStoreceiveregularcheck-upsandmonitoringfromtheirhealthcareprovidertoensureoptimaltreatmentandmanagementoftheircondition.Thismayincluderegulargynecologicalexams,bloodteststomonitorhormonelevels,andultrasoundstomonitorovarianfunction.

Inconclusion,PCOSisamultifacetedconditionthatrequiresacomprehensiveapproachtomanagementandtreatment.WhiletraditionalChinesemedicineandhormonaltherapyhaveshownpromisingresultsintreatingPCOS-relatedinfertility,lifestylechangessuchasexerciseandstressreductioncanalsoplayacrucialroleinmanagingthecondition.WomenwithPCOSshouldworkcloselywiththeirhealthcareprovidertodevelopanindividualizedtreatmentplanthataddressestheirspecificsymptomsandconcerns。InadditiontotraditionalChinesemedicineandhormonaltherapy,lifestylechangescansignificantlyimprovethemanagementofPCOS.WomenwithPCOSareofteninsulinresistant,meaningtheirbodiescannotuseinsulineffectivelytoregulateglucoselevels.Thiscanleadtohighbloodsugarandanincreasedriskoftype2diabetes.LifestylechangesthattargetinsulinresistancecanhelpmanagePCOSsymptomsandreducetheriskofdevelopingdiabetes.

Oneofthemosteffectivewaystoimproveinsulinsensitivityisthroughexercise.Infact,regularexercisehasbeenshowntoimproveinsulinsensitivitybyupto40%inwomenwithPCOS.Exercisecanalsohelpwithweightloss,anotherimportantfactorinmanagingPCOS.WomenwithPCOSareatanincreasedriskofobesity,whichcanexacerbateinsulinresistanceandotherPCOSsymptoms.Evenmodestweightlossof5-10%canimprovehormonalimbalancesandmenstrualirregularitiesinwomenwithPCOS.

StressreductiontechniquescanalsoplayacrucialroleinmanagingPCOS.Chronicstresscanincreaselevelsofthestresshormonecortisol,whichcandisruptthedelicatebalanceofhormonesinvolvedinPCOS.Relaxationtechniquessuchasyoga,meditation,deepbreathing,andmassagetherapycanhelpreducestressandimproveoverallwell-beinginwomenwithPCOS.

DietarychangescanalsohelpmanagePCOSsymptoms.WomenwithPCOSshouldaimtoeatabalanceddietrichinwholefoods,includingfruits,vegetables,wholegrains,andleanproteinsources.Theyshouldalsolimittheirintakeofprocessedandsugaryfoods,whichcancontributetoinsulinresistanceandweightgain.Somestudieshavealsoshownthatcertaindietarysupplements,suchasinositolandomega-3fattyacids,mayhelpimprovePCOSsymptoms.

Inconclusion,PCOSisacomplexconditionthatrequiresacomprehensiveapproachtomanagementandtreatment.WhiletraditionalChinesemedicineandhormonaltherapycanbeeffective,lifestylechangessuchasexercise,stressreduction,anddietarymodificationscanalsoplayacrucialroleinimprovingPCOSsymptomsandreducingtheriskofcomplications.WomenwithPCOSshouldworkcloselywiththeirhealthcareprovidertodevelopanindividualizedtreatmentplanthataddressestheirspecificsymptomsandconcerns。Inadditiontomedicalinterventions,lifestylechangescanhavesignificantbenefitsforwomenwithPCOS.Oneofthemostimportantmodificationsisadoptingahealthydiet.StudieshaveshownthatwomenwithPCOStendtohavehigherlevelsofinsulinresistance,whichcanleadtoweightgainanddifficultylosingweight.Adietthatfocusesonleanprotein,healthyfats,andcomplexcarbohydratescanhelpregulatebloodsugar,improvemetabolism,andreduceinflammation.Foodstoavoidincluderefinedcarbohydrates,sugarydrinks,andprocessedfoods.

ExerciseisanotherkeylifestylefactorthatcanhelpmanagePCOSsymptoms.Regularphysicalactivitycanimproveinsulinsensitivity,lowerinflammation,andregulatemenstrualcycles.Acombinationofcardiovascularexerciseandstrengthtrainingisrecommendedtobuildmuscleandimproveoverallfitness.Expertsrecommendatleast150minutesofmoderateexerciseperweek,suchasbriskwalkingorcycling.

Stressreductiontechniques,suchasmeditation,deepbreathing,oryoga,canalsohelpmanagePCOSsymptoms.Stresscausesthebodytoproducecortisol,whichcandisrupthormonebalanceandexacerbatesymptomssuchasacneandhairloss.Findingwaystomanagestressonadailybasiscanhavesignificantbenefitsforoverallhealthandwell-being.

Finally,womenwithPCOSshouldprioritizegettingenoughsleepeachnight.Sleepplaysacrucialroleinhormonebalanceandmetabolism.Chronicsleepdeprivationcanleadtoincreasedinsulinresistanceandweightgain.Expertsrecommendatleast7-8hoursofsleeppernightforoptimalhealth.

Insummary,PCOSisacomplexconditionthatrequiresacomprehensiveapproachtotreatmentandmanagement.Whiletraditionalmedicalinterventionscanbeeffective,lifestylechangessuchasexercise,stressreduction,anddietarymodificationscanhavesignificantbenefitsformanagingsymptomsandreducingtheriskofcomplications.WomenwithPCOSshouldworkcloselywiththeirhealthcareprovidertodevelopanindividualizedtreatmentplanthattakesintoaccounttheirspecificsymptomsandconcerns。Inadditiontothetraditionalmedicalinterventionsandlifestylechanges,therearealsonaturaltreatmentsandsupplementsthatcanhelpmanagePCOSsymptoms.SomeofthemostcommonnaturaltreatmentsforPCOSincludeacupuncture,herbalremedies,anddietarysupplements.

AcupunctureisatraditionalChinesemedicinepracticethathasbeenusedforcenturiestotreatavarietyofhealthconditions,includingPCOS.Acupunctureinvolvestheinsertionofthinneedlesintospecificpointsonthebodytostimulatetheflowofqi,orenergy,andimproveoverallhealthandwell-being.Studieshaveshownthatacupuncturecanhelpregulatemenstrualcycles,reduceinsulinresistance,andlowertestosteronelevelsinwomenwithPCOS.

HerbalremediesareanothernaturaltreatmentoptionforwomenwithPCOS.Anumberofherbs,includingsawpalmetto,chasteberry,andlicoriceroot,havebeenshowntohavebeneficialeffectsonPCOSsymptoms.Sawpalmettocanhelpreducetestosteronelevels,whilechasteberrycanhelpregulatemenstrualcyclesandreduceovariancysts.Licoricerootcanhelpreduceinsulinresistanceandimproveliverfunction,bothofwhichareimportantformanagingPCOSsymptoms.

DietarysupplementscanalsobehelpfulformanagingPCOSsymptoms.Anumberofsupplements,includinginositol,omega-3fattyacids,andvitaminD,havebeenshowntohavepositiveeffectsonPCOSsymptoms.InositolisaB-vitamin-likesupplementthatcanhelpimproveinsulinsensitivityandregulatemenstrualcycles,whileomega-3fattyacidscanhelpreduceinflammationandimprovelipidlevels.VitaminDisimportantforoverallhealthandcanhelpregulatemenstrualcycles,improveinsulinsensitivity,andreduceinflammation.

Inconclusion,PCOSisacomplexconditionthatrequiresacomprehensiveapproachtotreatmentandmanagement.Lifestylechangessuchasexercise,stressreduction,anddietarymodificationscanhavesignificantbenefitsformanagingsymptomsandreducingtheriskofcomplications.WomenwithPCOSshouldworkcloselywiththeirhealthcareprovidertodevelopanindividualizedtreatmentplanthattakesintoaccounttheirspecificsymptomsandconcerns.Naturaltreatmentssuchasacupuncture,herbalremedies,anddietarysupplementscanalsobehelpfulformanagingPCOSsymptoms.Withpropertreatmentandmanagement,womenwithPCOScanimprovetheirqualityoflifeandreducetheriskofcomplications。Inadditiontomedicaltreatments,lifestylemodificationscanalsoplayasignificantroleinmanagingPCOSsymptoms.MaintainingahealthyweightthroughregularexerciseandabalanceddietcanimproveinsulinsensitivityandreducetheseverityofPCOSsymptoms.Choosinglow-glycemicindexfoodssuchaswholegrains,fruits,andvegetablescanhelpregulatebloodsugarlevelsandreducetheriskofinsulinresistance.Avoidingprocessedandhigh-sugarfoodscanalsobebeneficial.

Regularexercisehasbeenshowntoreduceinsulinresistance,lowerbodyweight,andimprovehormonalimbal