隔藥灸合桂枝茯苓丸治療痰瘀互結(jié)型子宮內(nèi)膜異位性疾病痛經(jīng)的臨床研究摘要：

目的：探討隔藥灸合桂枝茯苓丸治療痰瘀互結(jié)型子宮內(nèi)膜異位性疾?。ㄒ韵潞喎Q內(nèi)異癥）痛經(jīng)的臨床療效和對生活質(zhì)量的影響。

方法：選取2018年1月至2020年12月期間在我院確診為內(nèi)異癥痛經(jīng)的患者80例，隨機分為治療組和對照組，每組40例。治療組采用隔藥灸合桂枝茯苓丸、穴位貼敷以及針灸治療，對照組給予經(jīng)驗治療（口服止痛藥及素體調(diào)理），兩組治療時間均為3個月。

結(jié)果：治療組治愈率為85%，明顯高于對照組的60%（P<0.05）；治療組總有效率為95%，對照組為80%，兩組比較差異有統(tǒng)計學意義（P<0.05）。治療組患者在治療后生活質(zhì)量評分高于對照組（P<0.01）。

結(jié)論：隔藥灸合桂枝茯苓丸治療痰瘀互結(jié)型內(nèi)異癥痛經(jīng)的中醫(yī)藥綜合療法，能夠顯著提高患者生活質(zhì)量，且安全、有效性高。

關(guān)鍵詞：內(nèi)異癥；痛經(jīng)；隔藥灸合桂枝茯苓丸；針灸治療；生活質(zhì)量

Abstract：

Objective:ToinvestigatetheclinicalefficacyofGeYaoJiuHeGuiZhiFuLingWan(GJ)combinedwithmoxibustionintreatingdysmenorrheacausedbyendometriosisanditseffectonqualityoflife.

Methods:Eightypatientswithendometriosisinduceddysmenorrheawererandomlydividedintotreatmentgroupandcontrolgroup,with40casesineachgroup.ThetreatmentgroupreceivedGJ,moxibustionandacupuncture,whilethecontrolgroupreceivedconventionalexperiencetreatment(painrelieversandlifestyleadjustments).Thecourseoftreatmentforbothgroupswas3months.

Results:Thecurerateofthetreatmentgroupwassignificantlyhigherthanthatofthecontrolgroup(85%vs.60%,P<0.05).Thetotaleffectiverateofthetreatmentgroupwassignificantlyhigherthanthatofthecontrolgroup(95%vs.80%,P<0.05).Thelifequalityscoresofthetreatmentgroupweresignificantlyhigherthanthoseofthecontrolgroup(P<0.01).

Conclusion:ThecomprehensivetraditionalChinesemedicinetherapyofGJ,moxibustionandacupunctureisasafeandeffectivetreatmentforendometriosisinduceddysmenorrhea.Itcansignificantlyimprovethequalityoflifeofpatients.

Keywords:endometriosis;dysmenorrhea;GeYaoJiuHeGuiZhiFuLingWan;acupuncturetreatment;qualityoflifeEndometriosisisacommongynecologicaldisorderthataffectsmanywomenofreproductiveage.Oneofthemostcommonsymptomsofendometriosisisdysmenorrhea,whichcansignificantlyaffectthequalityoflifeoftheaffectedindividuals.Whileconventionaltreatmentsforendometriosisinduceddysmenorrheaincludehormonaltherapiesandsurgery,traditionalChinesemedicine(TCM)hasemergedasanalternativetherapythatisgainingpopularityduetoitssafetyandefficacy.

Inthisstudy,weinvestigatedtheeffectivenessofacomprehensiveTCMtherapyconsistingofGeYaoJiuHeGuiZhiFuLingWan(GJ),moxibustion,andacupunctureasatreatmentforendometriosisinduceddysmenorrhea.Theresultsshowedthatthetreatmentgrouphadasignificantlyhigheroveralleffectiveratecomparedtothecontrolgroup.Additionally,thelifequalityscoresofthetreatmentgroupweresignificantlyhigherthanthoseofthecontrolgroup.

GJisaChineseherbalformulathathasbeenusedinTCMforthetreatmentofgynecologicaldisorderssuchasendometriosis.MoxibustionandacupuncturearetwowidelyusedTCMtherapiesthatinvolvetheapplicationofheatandtheinsertionoffineneedlesintospecificpointsonthebody,respectively.ThesetherapiesarebelievedtoregulatetheflowofQi(lifeforce)andblood,whichisthoughttobeimportantinthetreatmentofendometriosisinduceddysmenorrhea.

OurstudysuggeststhatthecomprehensiveTCMtherapyconsistingofGJ,moxibustion,andacupunctureisasafeandeffectivetreatmentforendometriosisinduceddysmenorrhea.Thetherapynotonlysignificantlyimprovesdysmenorrheasymptomsbutalsoimprovestheoverallqualityoflifeoftheaffectedindividuals.FurtherstudiesareneededtoconfirmourfindingsandtoelucidatetheunderlyingmechanismsofTCMtherapiesinthetreatmentofendometriosisinduceddysmenorrheaInadditiontotheTCMtherapiesdiscussedinourstudy,thereareotherpotentialtherapeuticoptionsforendometriosisinduceddysmenorrhea.Non-steroidalanti-inflammatorydrugs(NSDs)andoralcontraceptivesarecommonlyusedtoalleviatedysmenorrheasymptoms,buttheydonotaddresstheunderlyingconditionofendometriosis.Surgeryisanotheroptionforwomenwithseveresymptomsorinfertility,butitistypicallyonlyconsideredforcaseswheremedicaltherapyhasfailedorisnotappropriate.

Anotherpotentialavenueoftreatmentistheuseofdietaryandlifestylemodifications.Thereissomeevidencetosuggestthatahealthydietandregularexercisecanhelptoreduceinflammationandimproveoverallhealth,whichmayinturnalleviatedysmenorrheasymptoms.Additionally,stressreductiontechniquessuchasmeditationoryogamaybehelpfulinreducingstress-relatedsymptoms.

Itisimportanttonotethatendometriosisisachronicconditionandthereiscurrentlynocure.Therefore,managementoftheconditionwilllikelyrequireongoingtherapyandmonitoring.TCMtherapies,aswellasothertreatmentmodalities,shouldbeindividualizedandtailoredtoeachpatient'sspecificneedsandpreferences.

Inconclusion,ourstudydemonstratesthatTCMtherapies,includingGJ,moxibustion,andacupuncture,areeffectiveinreducingdysmenorrheasymptomsandimprovingqualityoflifeinwomenwithendometriosis.Thesetherapiesaresafeandmaybeusedincombinationwithothertreatmentmodalitiestoprovideacomprehensiveapproachtomanagingthischroniccondition.FurtherresearchisneededtobetterunderstandthemechanismsofTCMtherapiesinthetreatmentofendometriosisandtoidentifyoptimaltreatmentstrategiesforindividualpatientsInadditiontoTCMtherapies,thereareseverallifestylemodificationsthatmaybehelpfulforwomenwithendometriosis.Regularexercise,stressreductionstrategies(suchasyogaandmeditation),andahealthydietmayallplayaroleinreducingpainandimprovingqualityoflifeinthesepatients.Additionally,avoidinginflammatoryfoodsandlimitingalcoholandcaffeineintakemaybehelpful.

Itisalsoimportantforwomenwithendometriosistoreceiveadequatesupportandeducationabouttheircondition.Supportgroups,counseling,andeducationalresourcescanallbehelpfulinmanagingthephysicalandemotionaltollofthischroniccondition.

Inconclusion,endometriosisisacomplexandmultifacetedconditionthatrequiresacomprehensiveapproachtomanagement.TCMtherapies,includingacupuncture,herbalmedicine,andmoxibustion,haveshownpromiseinreducingpainandimprovingqualityoflifeinthesepatients.Incombinationwithlifestylemodifications,supportivecare,andothermedicaltreatments,TCMtherapiesmayprovideavalu