Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemE3-Hydroxybenzoicacid-d4Cat.No.:HY-W004049S分子式:C?H?D?O?分子量:142.15作用靶點:Isotope-LabeledCompounds;EndogenousMetabolite;HydroxycarboxylicAcidReceptor(HCAR)作用通路:Others;MetabolicEnzyme/Protease;GPCR/GProtein儲存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性3-Hydroxybenzoicacid-d4是氘標(biāo)記的3-Hydroxybenzoicacid(HY-W004049)。3-Hydroxybenzoicacid是一種有口服活性的內(nèi)源性代謝產(chǎn)物。3-Hydroxybenzoicacid是GPR81和GPR109A的激動劑。3-Hydroxybenzoicacid可作為應(yīng)激反應(yīng)脫敏劑。3-Hydroxybenzoicacid可用于抗炎和鎮(zhèn)痛研究。體外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattentionbecauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.REFERENCESLiuC,etal.3,5-Dihydroxybenzoicacid,aspecificagonistforhydroxycarboxylicacid1,inhibitslipolysisinadipocytes.JPharmacolExpTher.2012Jun;341(3):794-801.SabaAnjumKhanetal.PotentialAnti-Stress,AnxiolyticandAntidepressantLikeActivitiesofMono-HydroxybenzoicAcidsandAspirininRodents:AComparativeStudy.AustinJPharmacolTher.Volume3Issue3-2015.KhanSA,ChatterjeeSS,KumarV.Lowdoseaspirinlikeanalgesicandanti-inflammatoryactivitiesofmono-hydroxybenzoicacidsinstressedrodents.LifeSci.2016Mar1;148:53-62.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792/p>