早產(chǎn)兒低蛋白血癥12為早產(chǎn)兒輸注白蛋白能否獲益3擴(kuò)展：生后第1天總蛋白水平與早產(chǎn)兒結(jié)局相關(guān)目錄早產(chǎn)兒白蛋白水平2早產(chǎn)兒白蛋白水平ReadingRF,EllisR,FleetwoodA.Plasmaalbuminandtotalproteininpretermbabiesfrombirthtoeightweeks[J].EarlyHumanDevelopment,1990,22(2):81-87.MillerPW.Serumalbuminconcentrationsandoedemainthenewborn.[J].ArchivesofDiseaseinChildhood,1986,61(7):657-60.3早產(chǎn)兒白蛋白水平61pretermbabiesReadingRF,EllisR,FleetwoodA.Plasmaalbuminandtotalproteininpretermbabiesfrombirthtoeightweeks[J].EarlyHumanDevelopment,1990,22(2):81-87.4早產(chǎn)兒白蛋白水平61pretermbabiesReadingRF,EllisR,FleetwoodA.Plasmaalbuminandtotalproteininpretermbabiesfrombirthtoeightweeks[J].EarlyHumanDevelopment,1990,22(2):81-87.5早產(chǎn)兒白蛋白水平61pretermbabiesReadingRF,EllisR,FleetwoodA.Plasmaalbuminandtotalproteininpretermbabiesfrombirthtoeightweeks[J].EarlyHumanDevelopment,1990,22(2):81-87.6早產(chǎn)兒白蛋白水平195infantsof25to42weeksMillerPW.Serumalbuminconcentrationsandoedemainthenewborn.[J].ArchivesofDiseaseinChildhood,1986,61(7):657-60.7早產(chǎn)兒白蛋白水平早產(chǎn)兒白蛋白水平應(yīng)當(dāng)大于20g/L,35周左右達(dá)到25g/L,39周左右達(dá)到30g/L.8大家學(xué)習(xí)辛苦了，還是要堅(jiān)持繼續(xù)保持安靜9為早產(chǎn)兒輸注白蛋白能否獲益JardineLA,Jenkins-ManningS,DaviesMW.Albumininfusionforlowserumalbumininpretermnewborninfants[J].CochraneDatabaseofSystematicReviews,2004,3(3).10為早產(chǎn)兒輸注白蛋白能否獲益結(jié)論尚缺乏有力的證據(jù)去證明為存在低蛋白血癥的早產(chǎn)兒輸注白蛋白能夠改善死亡率，但同樣沒(méi)有足夠的證據(jù)指出白蛋白有顯著的副作用。11入選文獻(xiàn)的白蛋白水平haveaplasmaalbuminlevelbelow30g/Lat48to72hoursoflife。Studysubjectswerenewborninfantswhowereventilatordependantatlessthansevendaysofageandhadaserumalbuminlevelof≤30g/Llowbirthweightnewborninfantsatriskforrespiratorydistresswhowereacidaemicwithalowtotalserumproteinlevel(whethertheywerehypoalbuminaemicornotisunknown).僅有3篇文獻(xiàn)入選12為早產(chǎn)兒輸注白蛋白能否獲益早產(chǎn)兒早期，小于30g/L即輸注白蛋白不一定能獲益13總蛋白水平與早產(chǎn)兒嚴(yán)重不良結(jié)局相關(guān)SilviaI,FrancescoB,CatherineQ,etal.Totalplasmaproteininverypretermbabies:prognosticvalueandcomparisonwithillnessseverityscores.[J].PlosOne,2013,8(4):e62210.761infantswerestudied(totalproteinleveloflessthan40g/L),plasmaproteinmeasurementsondayoneoflifeinverypreterminfantssevereadverseoutcome：Thiswasdefinedasdeathorsevere(grade3or4)intraventricularhemorrhageorcysticperiventricularleukomalaciaoccurringbeforeinfants’dischargefromhospital14Conclusions:Earlyhypoproteinemiahasprognosticvalueforsevereadverseoutcomeinverypreterm,sickinfants.Total

plasmaproteinhas