第1題Whichofthefollowingisthemostreliablemethodfortumordiagnosis?AX-rayexaminationBPalpationCCTscanDPathologicaldiagnosis第2題Whatisthebeginningofpathomorphology?AEstablishmentoffluidpathologyB

EstablishmentofultrapathologyCEstablishmentoforganpathologyDEstablishmentofimmunopathology第3題Whichofthefollowingarethecontentsofpathology?AEtiologyBPathogenesisCPathologicchangesDProgressionandoutcomes正確答案：ABCD第1題A69-year-oldmanhasahistoryofhypertension.Theheartatautopsyisshownintheimages.Whichofthefollowingtermsbestdescribesthesemorphologicchangesoftheheartofthispatient?AMetaplasiaBHyperplasiaCHypertrophyDAtrophy第2題A45-year-oldwomanhasahistoryofdiffusenontoxicgoiter.Thefollowingpicturesshowedgrossandhistologicappearanceofherthyroid.Whichofthefollowingtermbestdescribesthesemorphologicchangesofherthyroid?AAtrophyBHyperplasiaCHypertrophyDMetaplasia第3題A40-year-oldmanloseshisrightkidneyduetomalignanttumor.ACTscan2yearslatershowsmarkedenlargementofhisleftkidney.Therenalenlargementisanexampleofwhichofthefollowingadaptativechanges?AAtrophyBDysplasiaCHyperplasiaDHypertrophy第4題A30-year-oldmansustainsaleftfemoralfracture.Thenhisleftleghasbeenimmobilizedforseveralweeks.Whichofthefollowingadaptationmostlikelyoccursinhisleftcalfmuscles?AAplasiaBhyperplasiaChypertrophyDAtrophy第5題A55-year-oldmanhasahistoryofgastroesophagealrefluxdisease.Histologicexaminationoftheabnormaltissueinhisesophagusshowsintestine-likeepitheliumsimilartoincompletelyintestinalizedgastricmucosa.Whichofthefollowingtermsbestdescribesthismorphologicchangeintheesophagusofthispatient?AMetaplasiaBHyperplasiaCHypertrophyDAtrophy第6題A38-year-oldmanexperienceschronic

atrophic

gastritis.Heundergoesuppergastrointestinalendoscopy,andabiopsyspecimenofhisstomachisobtained.Thehistologicphotographshowstheappearanceofthespecimen.Whichofthefollowingisthemostlikelydiagnosis?ASquamousmetaplasiaBMucosalhypertrophyCIntestinal

metaplasiaDAtrophyoflaminapropria第7題Thefollowingpicturesshowgrossandhistologicappearanceofscartissue.Thischangeismostlikelytoresultfromwhichofthefollowingalterations?AFattychangeBCellularedemaCHyalinechangeDAmyloidchange第8題Afterexperiencingmalaisefor6weeks,a42-year-oldmanseeshisphysician.SerologictestresultsarepositiveforHBsAg.Liverbiopsyshowsthelivercellswerediffuselyswollen,ballooning(shownintheimage).Whichofthefollowingisthemostlikelydiagnosis?ACelluaredemaBFattychangeCHyalineChangeDAmyloidChange第9題Inwhichofthefollowingconditionsismucoiddegenerationseen?ACardiovascularwallinacuterheumatismBMesenchymaltumorsCHypothyroidismDArteriolesinmalignanthypertension正確答案：ABC第10題Thefollowingpictureshowshistologicappearanceofhearttissuebiopsyfromaveryobeseman.Whichofthefollowingisthemostlikelydiagnosis?AFattychangeBFattyinfiltrationCEdemaDLipofuscinaccumulation第11題A70-year-oldmanhasahistoryofatherosclerosis.Histologicexaminationofhisheartisshownintheimage.Granularbluedepositscanbefoundinthewallofcoronaryartery.Whichofthefollowingisthemostlikelydiagnosisforthedeposits?AMucoidchangeBDystrophiccalcificationCMetastaticcalcificationDHyalinechange第12題A

60-year-oldmanhasalonghistoryofalcoholabuse.

Atautopsy,theliverenlargesandbecomesyellow,soft,andgreasy.SudanⅢstainofthelivertissueshowsorangeincolour.Histologicappearanceofhisliveratautopsyisshownintheimage.Whichofthefollowingisthemostlikelydiagnosisoftheliver?AEdemaBFattychangeCAmyloidosisDHyalinedegeneration第13題A55-year-oldmanexperiencedchestpainbeforehisdeath.Ahistologicsectionofleftventricularmyocardiumtakenatautopsyshowedinthefollowingimage.Whichofthefollowingisthemostlikelydiagnosis?ACoagulativenecrosisBHyperplasiaCHypertrophyDLiquefactivenecrosis第14題A33-year-oldwomanhashaddecreasedurineoutputforthepastweek.Laboratorystudiesshowserumcreatininelevelof4.3mg/dLandureanitrogenlevelof40mg/dL.Arenalbiopsyisperformedandthespecimenisexaminedusingelectronmicroscopy.Whichofthefollowingmorphologicchangesmostlikelysuggestsadiagnosisofacutetubularnecrosis?AMitochondrialswellingBPlasmamembraneblebsCMitosisDNuclearfragmentation第15題Achestradiographof40-year-oldmanshowsalesionintherightlung.Thelesionisexcised.Thefollowingimagesshowsthegrossandhistologicappearanceofthelesion.Cultureoftissuefromthelesiongrowsmycobacteriumtuberculosis.Whichofthefollowingisthemostlikelydiagnosis?AApoptosisBCaseousnecrosisCFatnecrosisDFattychange第16題A40-year-oldmanhasviralhepatitis.Ahistologicsectionofhislivershowsmorphologyofasinglecellinthefollowingimage.Whichofthefollowingisthemostlikelydiagnosis?ACelluaredemaBApoptosisCHyalineChangeDPathologicPigmentation第17題Aconstructionworkerhasbeenaccidentallystabbedwitharustynailofhisrightlegafewdaysearlier.Inrecent2days,thebodytemperaturewasover39°c,therightcalfishighlyswollen.Thereiscrepituswhentouchingtherightcalf.Thepatientissoonunconscious.Whichofthefollowingisthemostlikelydiagnosisofhisrightleg?AWetgangreneBLiquefactivenecrosisCDrygangreneDGasgangrene第18題Whichofthefollowingcanbetheconsequencesofnecrosis?ALysisandabsorptionBIsolationandeliminationCOrganizationDEncapsulationandCalcification正確答案：ABCDTissuerepair_test第1題A12-year-oldboysufferstraumaticinjurytotheskinonhisrightleg.Twodayslater,thewoundbecomepinkandgranularappearance.Thefollowingimageshowsthehistologicappearanceofthislesion.Whichofthefollowingisthemostlikelypathologicdiagnosis?AKeloidBScartissueCGranulationtissueDFibrinoidnecrosis第2題DuringtherepairprocessofthepatientdescribedinQuestion1,whichofthefollowingcelltypeswouldshowtheweakestregenerativecapacity?AVascularendothelialcellsBEpidermalcellsCSkeletalmusclecellsDFibroblasts第3題A62-year-oldmanhadchestpainpersistingfor4hours.Aradiographicimagingprocedureshowedaninfarctionoftheanteriorleftventricularwall.Laboratoryfindingsindicatedmyocardialinfarction.Whichofthefollowingpathologicfindingswouldmostlikelybeseenintheleftventricularlesionthreemonthslater?AFibrousscarBCompleteregenerationCAcuteinflammationDGranulationtissue第4題A20-year-oldmanlaceratedhisrightarmandrequiredsutures.Thesutureswereremoved1weeklater.Thesitebecamedisfiguredoverthenexttwomonths.Thefollowingpicturesshowthemacroscopicandhistologicappearanceofthelesion.Whichofthefollowingtermsbestdescribestheprocessthatoccurredinthisman?ACompleteregenerationBMetaplasiaCKeloidformationDNecrosis第5題A29-year-oldwomanunderwentCaesareansectionfourmonthsago.Aneatandlinearscarformedinasuturedwound.Whichofthefollowingtermsbestdescribestherepairprocess?AHealingbyfirstintentionBHealingbysecondintentionCCompleteregenerationDUnhealed第6題WhichofthefollowingnutritionalfactorsisrequiredforpropercollagenassemblyinthescartissueofthepatientdescribedinQuestion5?AVitaminEBVitaminCCVitaminBDVitaminA第7題A25-year-oldmansuffersaskinlacerationonhisrightkneebyaccident.Thewoundiscleanedbyhimself.Whichofthefollowingistheinitialeventinthewoundhealingprocess?AIngrowthofgranulationtissueBFormationofabloodclotCMacrophage-mediatedphagocytosisofcellulardebrisDDepositionofcollagen第8題Whichofthefollowingcelltypesfunctionsascontraction-mediatorinfacilitatingthehealingprocessofthepatientdescribedinQuestion7?ANeutrophilsBMacrophagesCFibroblastsDMyofibroblasts第9題WhichofthefollowingisthemostimportantfactorthatdetermineswhetherthewoundinthepatientdescribedinQuestion7willhealbyfirstorsecondintention?ATissuelossandappositionofwoundedgesBNutritionalstatusCBloodsupplyDMetabolicstatusLocalCirculatoryDisturbances_test第1題A

patient

suffered

from

acuteleftsidedheart

failure.

The

histological

appearance

of

the

patient’s

lung

tissue

is

shown

in

the

following

pictures.

Whichofthefollowingisthemostlikelydiagnosis?ACongestionandedemaofthelungBHemorrhageofthelungCNecrosisofthelungDEmbolismofthelung第2題Apatienthaschroniccongestionoflungs.Thefollowingpictureshowsthehistologicalappearanceofhislung.Theblackarrowspointtosomegiant

and

deep

stainingcells.The

pathological

pigment

in

the

cytoplasm

is:ABilirubinBHemosiderinCLipofuscinDMelanin第3題Duringhospitalization,a45-year-oldwomandevelopsthrombophlebitisinafemoralvein.Thefollowingimageshowsthemorphologyofthethrombusafter2weeks.Whichofthefollowingtermsbestdescribestheprocessseeninherfemoralveinafterrecoveryfromherthrombophlebitis:AAcuteinflammationBHaemorrhageCEmbolizationDOrganization第4題Redthrombusismostcommonin:AtheheadofthrombusBthemiddleofthrombusCtheendpartofthrombusDheartvalvesheartvalves第5題A55-year-oldwomanhasbeentreatedinthehospitalforpancreatitisforthepastthreeweeksandisfoundtohaveaswollenrightleg.Itistendertopalpationbutisnotwarm.Thisconditionismostlikelytobetheresultofwhichofthefollowingvascularcomplications?ACongestiveheartfailureBSepticembolizationCVenousthrombosisDArterialhyperemia第6題Inapatientwithmyocardialinfarction,thereisalesionintheventricularwall.Thefollowingimagesshowgrossandhistologicalappearanceofthelesion.Whichofthefollowingisthemostlikelydiagnosis?()ARedthrombusBWhitethrombusCMixedthrombusDHyalinethrombus第7題Apatientsuffersfromdisseminatedintravascularcoagulation(DIC).Thefollowingimageshowsthelesionmicrocirculation.Themajorcomponentofthislesion(blackarrow)is()APlateletBRedbloodcellCLeukocyteDFibrin第8題A62-year-oldmanhasexperiencedsubsternalchestpainuponexertionwithincreasingfrequencyoverthepast6months.Anelectrocardiogramshowsfeaturesconsistentwithischemicheartdisease.Hehasatotalserumcholesterolof262mg/dL.Byangiography,thereis75%narrowingoftheleftanteriordescendingartery.Whichofthefollowingvascularcomplicationsismostlikelytooccurinthispatient?AsystemicarteryembolusfromthrombosisinaperipheralveinBPulmonaryembolismfromthrombosisinaperipheralveinCPulmonaryembolismfromaleftventricularmuralthrombusDAsystemicarteryembolusfromaleftventricularmuralthrombus第9題Mostcommontypeofembolismis___AgasembolismBthromboembolismCfatembolismDamnioticfluidembolism第10題Thepulmonaryembolusmostlycomesfrom:AdeepveinsoflowerlimbBleftatriumCarterialDleftventricle第11題Apatientwithchronicleftheartcongestionhaspulmonarythromboembolism.Thefollowingimagesshowalesioninhislung.Whichofthefollowingisthemostlikelydiagnosis?(

)ALiquefactivenecrosisoflungBWhiteinfarctsoflungCAbscessoflungDHemorrhagicinfarctsoflung第12題Themostcommonreasonofinfarctis___AOcclusionofamajorarteryBArterialspasmCVenousocclusionDThrombosis第13題Whichofthefollowingorgansareeasilytodevelopwhiteinfarction?AKidney,Brain,IntestineBKidney,Lung,HeartCSpleen,Kidney,HeartDLung,Heart,Intestine第14題Apatienthasahistoryofrightheartfailure.Thefollowingimagesshowthegrossandhistologicappearanceofhisliver.Whichofthefollowingdescriptionarecorrectfortheliver?AFattychangecanbefound.BHemorrhagecanbeseen.CGrosslythecutsurfaceoftheliverlookslikenutmeg.DWithmanyregenerativenodules.正確答案：ABC第15題Whichofthefollowingconditionsillustratetheconceptofactivehyperemia?AHyperemiaafterdecompressionBBlushingfromembarrassmentCHyperemiaofskeletalmuscleduringheavyexerciseDGastrointestinalhyperemiaaftermeals正確答案：ABCD第16題Whichofthefollowingarethecausesofcongestion?ALocalvenouscompressionBLocalorsystemicvenousobstructionCCardiacfailureDIncreaseofvasoactivesubstances正確答案：ABC第17題Whichofthefollowingareconsequencesofchroniccongestionoflung?AinterstitialfibrosisBedemaChemorrhageDNecrosis正確答案：ABCD第18題Whichofthefollowingaremainpredisposingfactorsforthrombosis?AEndothelialinjuryBChangesinbloodflowCIncreasedcoagulabilityofbloodDThrombopenia正確答案：ABCInflammation_test第1題Whatsituationdoesinflammatiooccur（）AAnlylivingorganismBLlivingorganismwithavascularsystemCDeadorganismDSingle-celledorganism第2題Whichisthemostimportantpathologicfeatureofinflammation()ADegenerationBNecrosisCExudationDProliferation第3題WhichisthemostcommoncauseofinflammationAPhysicalagentsBMicrobiologicalagentsCChemicalagentsDImmunereactions第4題Theformationofexudateismainlydueto()AIncreasedintravascularhydrostaticpressureBDecreasedintravascularcolloidosmoticpressureCObstructionoflymphaticdrainageDIncreasedvascularpermeability第5題Whichstepofhemodynamicchangeiscausedbyincreasedvascularpermeability()AArteriolarvasodilationBArteriolarvasoconstrictionCIncreaseinbloodflowDBloodstasis第6題Whichisthemostcommonmechanismofincreasedvascularpermeability()AEndothelialcellcontractionBIncreasedtranscytosisCEndotheliuminjuryDLeakagefromthenewcapillaries第7題Whichofthefollowingitemswouldbeinfluencedbyadefectofintegrinexpressiononleukocytesintheprocessofleukocyteexudation()AMarginationBRollingCAdhesionDTransmigration第8題Whichofthefollowingchemicalsubstancesmaymakeleukocytesdirectionallymigratetowardstheinflamedareaalongaconcentrationgradient()ANitricoxideBROSCProstaglandinDC5a第9題WhichofthefollowingcelltypesisthefirstcelltotransmigratethroughthevesselwallintotheinflamedsiteAneutrophilBmacrophageCeosinophilDlymphocyte第10題A6-year-oldboyhasahistoryofrecurrentinfectionswithpyogenicbacteria.Geneticanalysisofperipheralbloodneutrophilsshowsadeficiencyinmyeloperoxidase.Anabnormalityinwhichofthefollowingprocessesisthemostlikelycauseofthisboy’srecurrentinfections()ALeukocyteadhesiontoendotheliumBLeukocytetransmigrationCRecognitionofmicrobesDKillingofingestedmicrobes第11題Opsonizationoccursinwhichstepoftheprocessofphagocytosis()ARecognitionandattachmentBEngulfmentCKillingoftheingestedmaterialDDegradationoftheingestedmaterial第12題Whichofthefollowingchemicalsubstancesismostlikelytoenhanceleukocyticphagocytosis()AHistamineandserotoninBComplementC3bandIgGCInterleukin-1andtumornecrosisfactorDIntegrinandselectin第13題Herpeszostervirusmaycauseskinlesionshowninthefollowingpicture.Whatisthemostlikelypathologicdiagnosisabouttheskinlesion(

)ASerousinflammationBFibrinousinflammationCSuppurativeinflammationDGranulomatousinflammation第14題Amandiedofuremia.Autopsywasperformed.Thegrossandmicroscopicappearancesofhisheartareshowninthepictures.Themostlikelydiagnosisis()APurulentpericarditisBserouspericarditisCConstrictivepericarditisDFibrinouspericarditis第15題Whattypeofinflammationdoespseudomembranousinflammationbelongto()ASerousinflammationBFibrinousinflammationCSuppurativeinflammationDGranulomatousinflammation第16題Suppurativeinflammationischaracterizedbyexudationofwhattypeofinflammatorycell()ALymphocyteBMacrophageCNeutrophilDEosinophil第17題Whichofthefollowingitemsbelongstoabscess()AAcutephlegmonousappendicitisBAcutepyogenicmeningitisCAcutebacillarydysenteryDCarbuncle第18題Whichofthefollowingitemsisconsistentwiththisdefinition:AnabnormaltractleadingfromafocusofdeepabscesstoacutaneousormucosalsurfaceAUlcerBFistulaCSinusDCavity第19題Whichofthefollowingdiseasesbelongstosuppurativeinflammation()ALobarpneumoniaBHairheartCAcutephlegmonousappendicitisDEpidemicencephalitisB第20題Thegrossappearanceofthecervicalmassisshowninthefollowingpicture.Microscopically,themasscontainshyperplasticepithelium,glands,andconnectivetissueaccompaniedbylargeamountoflymphocyteinfiltrate.Whatisthemostlikelypathologicdiagnosisofthemass(

)AInflammatorypolypBInflammatorypseudotumorCGranulomaDGranulationtissue第21題Whatisnodularcollectionofproliferatingmacrophagesandmacrophage-derivedcells()AInflammatorypolypBInflammatorypseudotumorCGranulomaDGranulationtissue第22題Surgicalsuturesmaystimulatetheformationofsomegiantcellswiththehistologicfeatureshowninthefollowingpicture.Whatisthegiantcellcalled(

)AEpithelioidcellBLanghansgiantcellCForeign-bodygiantcellDTumorgiantcell第23題WhataretheprinciplecellularcomponentsoftuberculousGranuloma()AEpithelioidcellsandforeign-bodygiantcellsBEpithelioidcellsandLanghansgiantcellsCMacrophagesandfibroblastsDMacrophagesandlymphocytes第24題WhichitemsarecorrectaboutchronicnonspecificinflammationATheprincipleinflammatorycellsaremacrophages,lymphocytes,andplasmacellsBTissueinjuryandtissuerepairproceedsimultaneouslyCChronicnonspecificinflammationoccurringinmucosamayforminflammatorypolypDMacrophage–Neutrophilinteractionsplayanimportantroleinthedevelopmentandmaintenanceofchronicinflammation正確答案：ABCNeoplasm_test1第1題A45-year-oldwomanpresentswithabdominalpainandvaginalbleeding.Ahysterectomyisperformedandshowsabenigntumoroftheuterusderivedfromsmoothmusclecell.Whatistheappropriatediagnosis?ALeiomyomaBAdenomaCTeratomaDHamartomaEFibroma第2題A50-year-oldmanpresentedwithaone-yearhistoryofprogressivedysphagia.Thefollowingimageshowsthemicroscopicappearanceofthetumorfoundinhisesophagus.Whatisthemostlikelydiagnosis?AAdenocarcinomaBMelanomaCLeiomyosarcomaDSquamouscellcarcinomaESquamouspapilloma第3題A63-year-oldmanhasnoticedincreasingmalaise.Onphysicalexamination,thestoolguaiactestispositive.Acolonoscopyisperformed,a4-cmmassisfoundinthesigmoidcolon.Oneweeklater,themassissurgicallyremoved,andthegrossandmicroscopicappearanceofthemassisshowninthefollowingpictures.Whichofthefollowingisthemostlikelydiagnosis?ASquamouscellcarcinomaBAdenocarcinomaCHamartomaDAdenomaESquamouspapilloma第4題A20-year-oldwomanhasanovariantumorexcised.Thesurgicalspecimenis10cmindiameterandcystic.Onmacroscopicexamination,thecysticmassisfilledwithblackhairandsebaceousmaterial.Histologically,squamousepithelium,glandularepithelium,cartilage,andfibrousconnectivetissuearepresentandresemblenormaltissuecounterparts.Whatisthemostlikelydiagnosis?AAdenomaBAdenocarcinomaCTeratomaDHamartomaEFibroadenoma第5題A30-year-oldwomanhasapositivestoolguaiactestduringaroutinephysicalexamination.Acolonoscopyisperformed,anda1.2-cm,circumscribed,pedunculatedmassonashortstalkisfoundintheupperportionofthedescendingcolon.Thefollowingimageshowsthemicroscopicappearanceofthemass.Whichofthefollowingtermsbestdescribesthislesion?ASarcomaBAdenomaCSquamouscellcarcinomaDFibromaELeiomyoma第6題A34-year-oldwomanundergoaroutinehealthexamination.APapsmearwasobtained,andtheresultreportedwasabnormal.Sheiscurrentlyasymptomaticandhasahistoryofhumanpapillomavirus(HPV)infection.Cervicalbiopsyspecimensareobtainedandthefollowingfigureshowsthemicroscopicappearance.Whichofthefollowingtermsbestdescribesthislesion?ACarcinomainsituBAdenocarcinomaCSquamouscellcarcinomaDHamartomaECINI第7題A55-year-oldmanpresentswithalumpinthesofttissueofhisleftshoulder.Physicalexaminationrevealsa0.8-cmsubcutaneoustumor.Thefollowingfigureshowsthemicroscopicappearanceofthetumor.Whatisthemostlikelydiagnosis?APapillomaBAdenomaCLeiomyomaDLipomaEFibroma第8題A73-year-oldmanhashadaslowlyenlargingnoduleonhislefteyelidfor3years.Thelesionisexcised,butmultiplefrozensectionsaremadeduringthesurgerytominimizetheextentoftheresectionandpreservetheeyelid.Themicroscopicappearanceofthelesionisshowninthefollowingpicture.Whatisthemostlikelydiagnosis?ASquamouscellcarcinomaBAdenocarcinomaCFibrosarcomaDLiposarcomaEBasalcellcarcinoma正確答案：E第9題A26-year-oldwomanhasnotedarednoduleontheskinofherneck.Shereportsthatthenodulehasbeenpresentformanyyearsandhasnotchangedinsize.Itisexcised,andthemicroscopicappearanceisshowninthefollowingimage.Whichofthefollowingneoplasmsisthislesionmostlikelytobe?AHemangiomaBFibroadenomaCLeiomyomaDLipomaEMelanoma第10題A32-year-oldwomanhadnoticedalumpinherrightbreast.Onphysicalexamination,a2.2-cm,circumscribed,freelymovablemassinthelowerouterquadrantispalpable.Themassissurgicallyremoved,andthemicroscopicappearanceofthemassisshowninthefigureatlow(A)andhigh(B)magnifications.Whatisthemostlikelydiagnosis?ALipomaBPapillomaCFibromaDFibroadenomaEHemangioma第11題An89-year-oldmandiespeacefullyinhissleep.Atautopsy,arestofpancreatictissueisidentifiedinthewalloftheloweresophagus.Thisfindingrepresentsanexampleofwhichofthefollowingconditions?ATeratomaBHemangiomaCChoristomaDPapillomaEAdenoma第12題A26-year-oldwomanpresentswithmultiplepapulesonthebackofherrighthand.Histologicexaminationofalesionisshowninthefigureatlow(A)andhigh(B)magnifications.Whatisthemostlikelydiagnosis?APapillomaBHemangiomaCLipomaDFibromaEAdenoma第13題WhichofthefollowingvirusesismostlikelyresponsibleforthedevelopmentoftheskinlesionsinQuestion12?AEpstein-BarrvirusBHumanpapillomavirusCCytomegalovirusDHumanherpesvirustype8EHerpessimplexvirustype2第14題A49-year-oldwomanpresentswitha3-monthhistoryofabdominaldiscomfortanddarkstools.Physicalexaminationshowspallorbutnoevidenceofjaundice.Abariumswallowradiographrevealsa“l(fā)eatherbottle”appearanceofthestomach.Thebiopsyisshowninthefigureatlow(A)andhigh(B)magnifications.Whichofthefollowingisthemostlikelydiagnosis?ABasalcellcarcinomaBChoristomaCLeiomyosarcomaDSquamouscellcarcinomaESignetringcellcarcinoma正確答案：E第15題A24-year-oldmanisadvisedtoseehisphysicianbecausegeneticscreeninghasdetectedadiseaseinotherfamilymembers.Onphysicalexamination,astoolsampleispositiveforoccultblood.Acolonoscopyisperformed,followedbyacolectomy.Thefollowingimageshowsthemacroscopicappearanceofthemucosalsurfaceofthecolectomyspecimen.Microscopicexaminationshowstheselesionsaretubularadenomas.Molecularanalysisofthispatient’snormalfibroblastismostlikelytoshowmutationinwhichofthefollowinggenes?AMLH1BRBCp53DAPCEBRCA1Neoplasia_test2第1題Whichofthefollowingfeaturesismostlikelydemonstratedbythemicroscopicappearanceofmalignanttumor?AAnaplasiaBAplasiaCHyperplasiaDDysplasiaEMetaplasia第2題Whichofthefollowingcharacteristicsismostlikelytobepredictedbythesub-clonesoftumorcells?AAngiogenesisBInvasivenessCDifferentiationDHeterogeneityEAneuploidy第3題A44-year-oldwomannotesa5cmdiameternon-tendermassintheupperouterquadrantofherleftbreast.Afineneedleaspirationofthismassisperformed,andcytologicallythecellsareconsistentwithinfiltratingductalcarcinoma.Another2cmnon-tendermassispalpableintheleftaxilla.Achestradiog