1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETebipenemCat. No.: HY-A0076CAS No.: 161715-21-5Synonyms: LJC 11036分式: CHNOS分量: 383.49作靶點: Bacterial作通路: Anti-infection儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 45 mg/mL (117.34 mM)H2O

2、 : 6.2 mg/mL (16.17 mM; Need ultrasonic and warming)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.6076 mL 13.0381 mL 26.0763 mL5 mM 0.5215 mL 2.6076 mL 5.2153 mL10 mM 0.2608 mL 1.3038 mL 2.6076 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL AC

3、TIVITY物活性 Tebipenem種可服的譜的碳 霉烯類抗素，能夠抑制蘭陽性 和蘭陰性菌，但對綠膿桿作。體外研究Tebipenem exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEsubstrate nitrocefin, and apparent Km and kcat values of 0.8 M and 0.03 min-1, respective

4、ly 1. Tebipenemshows potent activity against B. pseudomallei, with MIC50 and MIC90 values of both 2 mg/L 2. Tebipenemshows good activity against S. pneumoniae, with the MIC range of 0.25 g/mL in all of the S. pneumoniaeisolates 3.戶使本產(chǎn)品發(fā)表的科研獻 Biomed Res Int. 2018 Jul 2;2018:3579832.See more customer

5、validations on HYPERLINK / www.MedChemEREFERENCES1. Hazra S, et al. Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the -lactamase from Mycobacteriumtuberculosis. Biochemistry. 2014 Jun 10;53(22):3671-8.2. Seenama C, et al. In vitro activity of tebipenem against Burkholderi

6、a pseudomallei. Int J Antimicrob Agents. 2013 Oct;42(4):375.3. Li H, et al. In vitro antibacterial activities of two novel oral antibiotics, tebipenem and cefditoren, and other comparators againstcommunity-acquired respiratory tract infection-associated bacterial pathogens: A multicentre study in China. Int J Antimicrob Agents. 2014Jan;43(1):92-3.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: