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Extentandcompositionof toryCopyright?CGorrelEpithelialproliferationingingivitisCopyright?CGorrelApicalmigrationofepitheliumandbonelossinCopyright?CGorrelCopyrightCopyright?CGorrelPeriodontalPeriodontaldisease operateingingivaltissuestoprotectagainstlocalmicrobialattackandreventmicrooranismsortheirdamagingproductsformspreadingintoorinvadingthetissues或其產(chǎn)生的有害物質(zhì)蔓延或組織The‘protective’hostdefensereactionsdamagethetissuesandcontributetothetissuedestructionseenin inivitisandperiodontitisAnatomyoftheperiodontium–thepermeablejunctionalepitheliumthathasremarkablecellandfluiddynamics,withitsprimepurposetopreserveepithelialcontinuityacrossthehardandsofttissueinterfaceThe“defensiveprocesses”intheeriodontaltissuesoccurinres onsetoalargenumberandvarietiesofmicrobesthatr surfaceinabiofilmcommunity,closetoratherthanwithinthegingivaCopyright?CCopyright?CGorrelCopyrightCopyright?CGorrelThemicroorganismsinthebiofilm,especiallywhenpocketinghasoccurredareinacontinualstageoffluxTissuedestruction yr ltfromcombinationsofbacterialfactorswhichvaryovertimeThepathogenicityfmirrnimrl mhthehost’sinnateand/oradaptivecapabilitiesastothevirulenceofthebacteriathemselves TheWorldWorkshopinPeriodontologyReport1996)designatedA.itans,P.gingivalisT.forsythiaasperiodontal牙周病學(xué)研討會(1996)牙齦卟啉單胞菌和T.forsythia是牙周病的致病菌P.gulae??InPeriodontaldisease–uniqueWithinthesameindividualtheseverityofperiodontaltissueinjuryoftenvariesfromtoothtotoothandfromonetoothsurfacetoanother在同一個上,不同牙齒或者同一牙齒的不同表面SitespecificPeriodontalItisstillnotunderstoodwhyinsomepatientsthelesionsremainconfinedtothemarginalportionofthegingivaltissues,whileinothersusceptiblepatientstheyprogresstoinvolvemoreapicalportionsoftheperiodontiumandcauselossofperiodontalatta entandbonePeriodontalTheThesameholdstrueforsiteswithinasusceptible Imbalanceofhost-parasiterelationshipisoccurringinthedestructivelesionsGingivalGingival Copyright?CGorrelCopyrightCopyright?CG

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