1、Active Micro Technologies艾緹微過去十年,消費者意識到全球法令章規(guī)越來越嚴格,過敏膚質(zhì)及日常用于化妝品及個人保養(yǎng)品配方中的防腐劑,消費者開始要求使用天然品.要求各種更新及替代方案之需求那正是Active Micro Technologies, LLC公司所重視的.我們公司合成化妝品功能原料成分,取代化學(xué)防腐劑的需求21st Century Antimicrobials21世紀抗微生物劑Consumer preference 消費者喜好Moving away from synthetic preservatives (Parabens, Phenoxyethanol, F

2、ormaldehyde Donors)去除合成的防腐劑（尼泊金酯，苯氧乙醇，甲醛釋放體）Regulations 法規(guī)Tighter global regulations 更嚴格的全球法規(guī)Banned and restricted ingredients 禁止和限制的成分3Natural antimicrobials in the market目前天然防腐劑的市場情況Lack of broad spectrum activity缺乏廣譜抑菌活性Additional materials such as potassium sorbate are required for achieving bro

3、ad spectrum activity需要添加山梨酸鉀等額外的防腐劑才能獲得廣譜抑菌活性A mixture of various ingredients is required for optimum preservation需要各種成分的復(fù)配才能達到最佳的防腐效果Formulation Issues配方方面Unstable at high and low pH and temperatures高或低的pH值和溫度下都不穩(wěn)定Strong cationic or anionic charges強離子性Dark colors顏色深 AMTs Formulating ApproachActive

4、Micro Technologies, LLC艾緹微公司并已發(fā)展出抗菌抑菌及對皮膚有功能性多重效果的產(chǎn)品這項抑菌自我防護功能可以讓化妝品不必使用添加防腐劑Multifunctional Products多功能產(chǎn)品Active Micro Technologies, LLC公司正不斷地改善增加保存、天然的植物抑菌劑系列. 以達成客戶需求天然防腐和天然抗微生物的化學(xué)防腐劑替代品我們創(chuàng)造原料的成分是抗菌同時可以提供化妝品活性的可能性 化妝品原料開發(fā)的多功能性將使我們能夠重新定義在21世紀化妝品的保存方式 Potential Sources前瞻性原料: 勝肽-植物提取抗菌抑菌對皮膚有功能性多重效果的產(chǎn)

5、品勝肽原料:保濕除皺美白抗炎植物提取:美白抗痘抗氧化保濕7Leucidal Liquid SF 亮肽抗菌液Peptide isolated from bacteria 從明串珠菌中得到的勝肽（細菌素）Moisturizes and tightens the skin, lightening and anti-inflammatory保濕和緊致肌膚，亮白肌膚及抗炎Exhibits broad spectrum anti-microbial activity呈現(xiàn)廣譜的抑菌活性Avian Flu Study in Korea 韓國的禽流感研究Studied Chickens infected wit

6、h Avian Flu研究感染禽流感的雞Variable: chickens fed kimchi變量組：飼喂泡菜的雞Control: chickens fed standard feed對照組：飼喂標準飼料的雞Results: variable had better rate of recovery結(jié)果：變量組有更好的恢復(fù)率Our inspiration 我們的靈感來源Marketing Aspects 市場宣稱Both kimchi and Leucidal are fermented with the same species of bacteria 泡菜和亮肽抗菌液是用同一種細菌發(fā)酵的

7、Allows us to capitalize on perceived benefits of kimchi利用泡菜的功能來宣傳Natural ingredient trend天然益生菌來源Peptide trend勝肽趨勢Preservative Free無防腐添加Efficacy Data 保濕功效數(shù)據(jù)in vivo moisturization data 體內(nèi)保濕數(shù)據(jù)NOVA DPM Impedance Meter NOVA DPM電阻抗儀Subjects: 5 (m/f) Ages: 24 41受試者: 5人（男/女） 年齡：24-41Test Site: Volar forearm

8、測試部位：前臂內(nèi)側(cè)Test Material: 測試物質(zhì)1% Leucidal Liquid SF in base cream 含1%亮肽抗菌液的基礎(chǔ)膏霜Base cream基礎(chǔ)膏霜Duration of Study: 28 Days實驗期：28天Leucidal Liquid SF 保濕效果測試Peptides have been found to provide moisturizing benefits勝肽提供保濕作用 LeucidalLiquid SF was evaluated to determine if it could provide moisturization benef

9、its檢測亮肽抗菌液是否能提供保濕作用The addition of 1% LeucidalLiquid SF to a generic cream provided a significant increase in skin moisturization.添加1%亮肽抗菌液的膏霜大幅增加了皮膚的保濕性 Results 結(jié)果基礎(chǔ)霜的保濕結(jié)果基礎(chǔ)霜+1% SF 的保濕結(jié)果12Efficacy DataOrganismsE. coliP. aeruginosaS. aureusA. brasiliensisC. albicansInoculum (initial)7.0 x1067.0 x105

10、5.1x1061.7x1064.7x106Day 0 99.999%99.857% 99.999%99.996% 99.997%Day 799.999%99.999% 99.999%99.999% 99.999%Day 1499.999%99.999%99.999%99.999%99.999%Day 2199.999%99.999%99.999%99.999%99.999%Day 2899.999%99.999%99.999%99.999%99.999%Inoculum(re-inoculated)8.2x1071.6x1061.0 x1063.3x1061.7x106Day 799.999%

11、99.985% 99.987%99.977%99.975%Day 1499.999%99.999%99.999%99.999%99.999%Day 2199.999%99.999%99.999%99.999%99.999%Day 2899.999%99.999%99.999%99.999%99.999%MIC Data挑戰(zhàn)測試典型膏霜配方MIC%大腸桿菌E. coli0.75金黃色葡萄球菌S. aureus1.00綠膿桿菌P. aeruginosa1.00白色念珠菌C. albicans0.75黑曲霉菌1.0014Leucidal Liquid SF 提供廣譜抗菌活性 提供優(yōu)質(zhì)的膚感 具有與其

12、他化妝品原料優(yōu)異的配伍性能 抗衰及保濕功效 益生菌的概念，天然，安全無添加防腐宣稱配方建議優(yōu)點建議添加量: 2 5%溶解性: 水溶 溫度穩(wěn)定性: 70C- 最好在產(chǎn)品乳化完成后加入PH范圍: 3 - 8Leucidal Liquid SF 產(chǎn)品信息Code: M15019CHIINCI Name: LEUCONOSTOC/RADISH ROOT FERMENT FILTRATEINCI名稱：明串球菌/蘿卜（RAPHANUS SATIVUS）根發(fā)酵產(chǎn)物濾液INCI Status: 符合建議添加量: 2.0 5.0%建議應(yīng)用配方:抗衰保濕等護膚產(chǎn)品，無添加宣稱Tomorrows vision To

13、day!Water/Eau, Sodium Cocoamphoacetate, Glycerin, Lauryl Glucoside, Sodium Cocoylglutamate, Sodium Lauryl Glucose Carboxylate, Coco-Betaine, Cocamidopropyl Betainamide Mea Chloride, PEG-120 Methyl Glucose Dioleate, Panthenol, Ethylhexylglycerin, Leuconostoc/radish root ferment filtrate, PEG-40 Hydro

14、genated Castor Oil, Hydrolyzed Wheat Gluten, Citric Acid, Butylene Glycol, Allantoin, Citrus limonum (Lemon) Peel Oil, Rosmarinus officinalis (Rosemary) Leaf Oil, Cymbopogon nardus (Citronella) Oil, Mentha arvensis Leaf Oil, Abies sibirica Oil, Cinnamomum camphora Oil, Aniba rosaeodora (Rosewood) Wo

15、od Oil, Eugenia caryophyllus Oil, Chlorphenesin, Disodium EDTA, Citris grandis (Grapefruit) Peel Oil, Xanthan Gum, Peumus boldus Leaf Extract, Sodium Copper Chlorophyllin, Chamomilla recutita (Matricaria) Flower Extract, Arctium majus Root (Burdock) Extract, Arnica montana Flower Extract, Urtica dio

16、ica (Nettle) Extract, Equisetium arvense (Horsetail) Extract, Betula alba Leaf Extract, Salvia officinals (Sage) Leaf Extract, Aloe barbadensis (Aloe Vera) Leaf JuiceIngredientsG.M. Collin Oxygen PurActive法國歌蓮 + Mild Cleansing GelProduct DescriptionA fragrance and alcohol-free gentle foaming gel cle

17、anser. Formulated through the synergy of seven plant extracts and other natural ingredients, this cleansing gel removes excess sebum, impurities and make-up leaving skin soft, fresh and clear. Detoxifies, revitalizes and tightens pores. Prevents and protects the skin from an accumulation of bacteria

18、 that results in problem skin（阻止皮膚受細菌傷害）. For use in both the morning and evening.Tomorrows vision Today!Water/Eau, Hexylene Glycol, Butylene Glycol, PEG-60 Almond Glycerides, Caprylyl Glycol, Glycerin, Carbomer, Nordihydroguaiaretic Acid, Oleanolic Acid, Zinc Acetylmethionine, Leuconostoc/radish ro

19、ot ferment filtrate, MagnesiumAspartate, Zinc Gluconate, Copper Gluconate, PEG-40 Hydrogenated Castor Oil, Peumus boldus Leaf Extract, Xanthan Gum, Aloe barbadensis (Aloe Vera) Leaf Juice, Pelargonium graveolens (Geranium) Oil, Mentha arvensis Oil, Cymbopogon martini (Palma Rosa) Oil, Citrus auranti

20、um dulcis (Orange) Oil, Disodium EDTA, Potassium Sorbate, Allatoin, Potassium Ascorbyl, Tocopheryl Phosphate (Vitamin C & Vitamin E), Sodium Copper ChlorophyllinIngredientsG.M. Collin PurActive Treating法國歌蓮 LotionProduct DescriptionPurActive Treating Lotion is an alcohol and fragrance-free lotion wi

21、th seven plant extracts and 100% natural ingredients100%純天然原料. This lotion was designed to purify, detoxify and soothe the skin亮白、使皮膚光滑. PurActive Treating Lotion promotes an even complexion for skin that appears smooth and matte(消光) to the finish. It also helps maximize skin care benefits.Tomorrows

22、 vision Today!Water, Cetearyl Alcohol, Glycerin,Butyrospermum Parkii (Shea Butter), Ethylhexyl Palmitate, Sesamum Indicum (Sesame) Seed Oil, Fragrance, Glyceryl Stearate, PEG-100 Stearate, Dimethicone, Glycol Stearate, Phenethyl Alcohol, Caprylyl Glycol, Prunus Armeniaca (Apricot) Kernel Oil, Carbom

23、er, Xanthan Gum, Butylene Glycol, Sodium Hydroxide, Disodium EDTA, Prunus Armeniaca (Apricot) Fruit Extract, Tocopherol, Linalool, Limonene, Citronellol, Leuconostoc/radish root ferment filtrate,Alpha-Isomethyl Ionone, Geraniol, Mica, Titanium Dioxide, Iron Oxides, Red 4.IngredientsThe Body Shop 美體小

24、鋪 LotionProduct DescriptionBest if you want to: Get your skin party-ready with a light, creamy moisturizer that softens and smoothes, leaving skin shimmering and delicately sented with the sensual fragrance of apricot and plum.Best for: normal skinHow it works:- Black velvet apricot extract adds a f

25、estive juicy fragrance.- Skin-nourishing apricot and plum kernel oils are rich in Vitamin A, Vitamin E and anti-oxidents.- Community Trade shea butter has antioxidant vitamins A and E to help protect and nourish skin.- Community Trade sesame oil moisturizes and softens skin.（得到柔軟滋潤的肌膚）Tomorrows visi

26、on Today!Water (Aqua), Glycerin, Butylene Glycol, Isopropyl Isostearate, Cetearyl Alcohol, Butyrospermum Parkii (Shea Butter),Dimethicone, Cyclohexasiloxane, Glyceryl Polyacrylate, Hydroxydecyl Ubiquinone, Leuconostoc/radish root ferment filtrate, Guanidine HCL, Lactic Acid, Tocopheryl Acetate, Capr

27、ic/Caprylic Triglycerides, Cetyl Palmitate, Glycine Soja Lipids (Soybean), Hydrogenated Jojoba Oil, Hydrogenated Olive Oil, Hydrogenated Soybean Oil, C12 15 Alkyl Benzoate, Euterpe Oleracea Sterols, PEG 40Hydrogenated Castor Oil, Propylene Glycol, Urea,Phospholipids, Phytosterols, Polyphosphorylchol

28、ine Glycol Acrylate, Tripeptide 1, Glucose, Octadecenedioic Acid, Ceteth 20, PEG 100 Stearate, Sodium Laureth Sulfate,IngredientsElizabeth Arden / Prevage伊利莎白雅頓Total Transform Anti-aging MoisturizerProduct DescriptionHigh performance moisturizer with Idebenone, clinically proven as the most powerful

29、 antioxidant* and Tripeptide Complex zeros in on your bodys anti- aging skincare needs.Over 85% of consumers tested observed a reduction in the look of minor scars, stretch marks and dimpled skin and 67% of consumers also saw a reduction inthe appearance of age spots and discolorations.Its definitel

30、y not just another moisturizer youll see a difference in just six weeks: skin looks smoother, firmer, totally transformed.（六周后將得到明顯的皮膚改觀）Tomorrows vision Today!Water (Aqua), Leuconostoc/Radish RootFerment Filtrate, Pelargonium Graveolens (Geranium) Flower Oil, Salvia Sclarea (Clary) Oil, Rosmarinus Officinalis (Rosemary) Leaf Oil, Anthemis Nobilis (Chamomile) Flower Oil, Rosa Centifolia (Rose) Flower Extract, Viola Odorata (Sweet Violet) Extract, Cymbidium Grandiflorum (Orchid) Flower Extract, Lycium Barbarum (Goji Berry) Fruit Extract, Punica Granatum (P