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BENIGNFOCALLIVERLESIONSAbscessesandHaematomaClinicalfeaturesofanabscess(膿腫)Patientspresentwithfever,oftenaccompaniedbyrightupperquadrant(RUQ)painandvomiting(嘔吐).Abnormalliverfunctiontests(LFTs)andanaemia(貧血)canalsobepresent.Theclinicalhistoryhelpsthesonographer(超聲醫(yī)生)toestablishthenatureofthefocallesionandaetiologyoftheabscess.Abscessesofanytypemaybesolitaryormultiple.Becausetheultrasoundappearancesofabscessescanbesimilartothoseofnecrotic(壞死的)tumoursorhaematoma(血腫),theclinicalpictureisofparticularimportancetothesonographer.UltrasoundappearancesHepaticabscessesmaydisplayavarietyofacousticfeatures.Theirinternalappearancesvaryconsiderably.Intheveryearlystagesthereisazoneofinfected,oedematous(水腫的)livertissuewhichappearsonultrasoundasahypoechoic,solidfocallesion.Astheinfectiondevelops,thelivertissuebecomesnecrotic(壞死的)andliquefactiontakesplace.Theabscessmaystillappearfullofhomogeneousechoesfrompusandcanbemistakenforasolidlesion,butasitprogresses,thefluidcontentmaybecomeapparent,usuallywithconsiderabledebris(碎片)withinit.Becausetheyarefluid-filled,abscessesdemonstrateposteriorenhancement(Fig.4.7A).Themarginsofanabscessareirregularandoftenill-definedandfrequentlythickened.Theinflammatorycapsuleoftheabscessmaydemonstratevascularity(多血管)oncolourorpowerDopplerbutthisisnotinvariableanddependsonequipmentsensitivityandsizeofthelesion.Infectionwithgas-formingorganismsmayaccountforthepresenceofgaswithinsomeliverabscesses(Fig.4.7B).Thegascontainedwithinthislargeabscessintherightlobeoftheliverobscuresthefullextentofthelesion.(Largeabscesseslikethis,whichcontaingas,maymimictheacousticappearancesofnormalbowel.)TherearethreemaintypesofabscessPyogenicabscess(化膿性膿腫)Amoebicabscess(阿米巴膿腫)Candidiasisabscess(念珠菌膿腫)PyogenicabscessTheseformasaresultofinfectionenteringtheliverthroughtheportalvenoussystem(門靜脈系統(tǒng)).Mostcommonly,appendiceal(闌尾的)ordiverticular(憩室的)abscessesareresponsible,butintrahepaticabscessesarealsoseeninimmunosuppressed(免疫抑制的)patientsandfollowingpostoperativeinfection.Theyarefrequentlymultiple,andthepatientmustbecloselymonitoredafterdiagnosistopreventrapidspread.Pyogenicabscessisstillconsideredalethal(致命的)condition,whichhasincreasedinrecentyearsduetoincreasinglyaggressivesurgicalapproachestomanyabdominalneoplasms.4AmoebicabscessThisisaparasitic(寄生蟲的)infectionwhichisrareintheUK,butfoundfrequentlyinpartsofAfrica,IndiaandthesouthernpartsoftheUSA.Suspicionshouldberaisedwhenthepatienthasvisitedthesecountries.Itisusuallycontractedbydrinkingcontaminatedwater(污水)andinfectsthecolon(結(jié)腸),ulceratingthewallandsubsequentlybeingtransportedtotheliverviatheportalvenoussystem.ManagementofhepaticabscessesAnultrasound-guidedaspiration(吸引術(shù))toobtainpusforcultureisusefulforidentifyingtheresponsibleorganism.Aspirationcombinedwithantibiotictherapyisusuallyhighlysuccessfulforsmallerabscessesandultrasoundisusedtomonitortheresolutionoftheabscessesintheliver.Ultrasound-guideddrainageisusedforlargelesions,andsurgicalremovalisrarelyrequired.Furtherradiologymaybeindicatedtoestablishtheunderlyingcauseandextent,forexamplebariumenema(鋇劑灌腸)orCT,particularlyifamoebicinfectionissuspected.HaematomaTheliverhaematomamayhavesimilaracousticappearancestothoseofanabscess,butdoesnotsharethesameclinicalfeatures.Ahaematomaistheresultoftrauma(創(chuàng)傷)(usually,therefore,viatheAccidentandEmergencydepartment)butthetraumamayalsobeiatrogenic(醫(yī)源性),forexamplefollowingabiopsy(活檢)procedure(hencethevalueofusingultrasoundguidancetoavoidmajorvesselsintheliver)orsurgery.Intrahepatichaematomafollowingaroadtrafficaccidentwithribfractures.Thelesionisrelativelyfreshandcontainssomelow-levelechoes.2-day-oldsubcapsularhaematoma.Thecollectionbecameprogressivelysmallerandhyper
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