從高血糖與糖尿病周圍神經(jīng)病變的關系反思研究和控制策略北京大學人民醫(yī)院

紀立農(nóng)ChinaCardiometabolicRegistries2Nation-wide,prospective,registryseriesdesignedtobetterunderstandclinicaloutcomesof

currenttreatmentofcardiovascularandmetabolicdiseasesinrealworldsettingsOrganizedbyChineseMedicalDoctorAssociationsSupervisedbyCCMRInternationalAdvisoryBoardManagedbyVitalStrategicResearchInstitute

ChinaCardiometabolicRegistries

研究者會議

2011年5月14-15日中國2型糖尿病患者心血管疾病危險因素的縱向隊列研究

中國老年學學會（GSC）主辦

中國醫(yī)師協(xié)會心血管內(nèi)科醫(yī)師分會(CCCP)協(xié)辦中國醫(yī)師協(xié)會內(nèi)分泌及代謝科醫(yī)師分會(CEA)協(xié)辦中國心血管代謝病系列研究(CCMR)組織及專家委員會

指導華斯泰生命策略研究所/上海華斯泰醫(yī)學咨詢有限公司(VSRI)執(zhí)行默沙東(中國)有限公司贊助NationwideAssessmentofCardiovascularRiskFactors--BloodPressure,BloodLipid,andBloodGlucoseinChinesePatientswithType2DiabetesLinongJi

PekingUniversityPeople’sHospital

OnbehalfofCCMRAdvisoryBoardJietal.AJM，2013，inpressStudyObjectives–PrimaryPrimaryObjectiveToassessthelevelofcontrolofCVDriskfactors,includingbloodpressure,bloodlipid,andbloodglucose,inoutpatientswithtype2DMin6representativeregionsinChinaandinthreetiersofhospitalsToidentifythegapbetweenrealworlddiabetesmanagementsituationandstandardofcare4Jietal.AJM，2013，inpressStudyObjectives-SecondarySecondaryObjectivesToassesstheproportionofmicrovascularandmacrovasclardiabeticcomplicationsinoutpatientswithtype2DMToassessreal-lifetreatmentpatternsinoutpatientswithtype2DMToassesstheproportionofhypoglyecemiaunderthecurrenttreatmentToassesstheinfluencingfactors(hospitalclassification,regionaldistribution,medicalhistory,educationallevelandothers)onDMtreatmentoutcomes5Jietal.AJM，2013，inpressNon-interventional,observational,cross-sectionaldesignType2diabetesdiagnosedfor6monthsorlongerAmbulatorypatientsfromendocrinology,cardiology,nephrologyclinicsinall3tiersofhospitals(Tier1,2,and3)locatedinall6mainregionsinChinaEstimatedsamplesizewas25,000patientsinordertohavesufficientpowertodetectthedifferenceoftheprimaryassessmentineachregion666StudyDesignTargetedtoenroll25,000patientsJietal.AJM，2013，inpressDistributionofParticipatingHospitals7NumberofsitesineachregionwasproportionaltothepopulationintheregionNationalRegionsTier1Tier2Tier3SUMNorthEast46616North46818East57618NorthWest45514SouthWest59721CentralSouth45716SUM263839103Jietal.AJM，2013，inpressCharacteristicsofstudysubjects8NumberPercentage(%)All25454100.0Age(yr)<651385554.5

>651159945.5GenderMale1195547.0Female1349953.0ResidentUrban2277689.5Rural267810.5BMI(kg/m2)<241061741.7

>241483558.3Meanage=62.6+/-11.9yearsJietal.AJM，2013，inpressDistributionofCVDRiskFactors28%ofthepatientshadT2Donly60%ofthepatientsalsohadHTN(T2D+HTN)About42%ofthepatientsalsohadDYLP(T2D+DYLP)About30%ofthepatientshad“3B”:highbloodglucose,bloodlipid,

andbloodpressure(T2D+HTN+DYLP)9T2D=type2diabetes,HTN=hypertension,DYLP=dyslipidemiaJietal.AJM，2013，inpress

DiabetesDurationandComplications

10Prevalenceofdiabeticcomplicationsisproportionaltodurationofdiabetes(%)DurationofDiabetesJietal.AJM，2013，inpressDiabeticComplicationsandCVD

RiskFactors11(%)Jietal.AJM，2013，inpressCallaghanBC

，etal.CochraneDatabaseSystRev.2012CallaghanBC

，etal.CochraneDatabaseSystRev.2012CallaghanBC

，etal.CochraneDatabaseSystRev.2012CallaghanBC

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