CARDIOVASCULAREVALUATIONDR.LiangQiAPATIENTCASEEXAMPLE4.Doyouexperienceanginaorshortnessofbreathatrest,onlywithactivity/exercise,orbothatrestandwithactivity/exercise?5.Ifyouexperienceanginaorbecomeshortofbreathduringactivityorexercisecouldyoupleasedescribethetypeofactivityorexercisewhichproducesyouranginaorshortnessofbreath?6.Canyoudescribeyouranginaorshortnessofbreath?Canyouhelpmeunderstandyouranginaorshortnessofbreathbypointingtothenumbers1through4todescribethelevelofanginayouexperienceatrestandexerciseorbypointingtoyourlevelofshortnessofbreathusingthis10-pointscaleorbymarkingthisvisualanalogscale?7.CouldIfeelyourpulsetodetermineyourheartrateandthestrengthofyourpulse?8.CouldIplacethisfingerprobeonyourindexfingertoobtainanoxygensaturationmeasurement?9.CouldIplacetheseelectrodesonyourchesttoobtainasimplesingle-leadelectrocardiogram(ECG)?10.CouldItakeyourbloodpressurewhileyouareseatedandthencompareittothebloodpressurewhileyouarelyingdownandthenstanding?Iwouldalsoliketoobserveyourpulse,oxygensaturation,ECG,andsymptomswhenyouarelyingdownandstanding.11.CouldIlistentoyourheartandlungswithmystethoscope?WhileIdothisIwillconcentrateonwatchingyourECGsothatIcanidentifyyourheartsoundsandanychangesintheECGwhileyouarebreathingdeeplywhenlisteningtoyourlungs.12.CouldIplace1ofmyhandsonyourstomachand1handonyourupperchesttodeterminehowyoubreathe?13.CouldIplacemyhandsonthelowermostribsoneachsideofyourchesttodeterminehowyoubreathe?14.CouldIplacemyhandsonyourbacktodeterminehowyoubreathe?15.CouldIwrapmytapemeasurearoundyourchestatseveraldifferentsitestodeterminehowyoubreathe?17.CouldImeasurethestrengthofyourbreathingmusclebyhavingyouplacethismouthpieceinyourmouthandbreatheinandoutasdeeplyandasforcefullyasyouareable?18.Iwouldlikeyoutonowperformtheactivityorexercisewhichproducesyouranginaorshortnessofbreath.Couldyoupleasedothisnow?PhysicalTherapyExaminationMedicalInformationandRiskFactorAnalysislisteningtothepatientspasthistoryandprimarycomplaintsiscriticalintheexaminationprocess.ExaminationsofPatientAppearancecategorizedbyspecificsignsandsymptomsAngina-MethodsToEvaluateAnginafromNonanginalPainIfasuspectedanginalpainchanges(increasesordecreases)withbreathing,palpationinthepainfularea,ormovementofajoint(ie,shoulderflexionandabduction)itisverylikelythatthepainisNOTangina.Angina-MethodsToEvaluateAnginafromNonanginalPainitcanbeworsenedbyphysicalexerciseoractivity.Therefore,ifthesuspectedanginalpainisunchangedwiththepreviouslycitedmaneuversandthepainoccurredwithexertion,itisSUSPECTforangina.Ifthesuspectedanginalpainisunchangedbythesemaneuvers,ifthepainoccurredwithexertion,andifthepaindecreasesorsubsideswithrest,itisverylikelythatthepainISangina.Finally,ifthesuspectedpaindecreasesorsubsideswithnitroglycerin,itisevenmorelikelythatthepainISangina."Other"SymptomsofHeartDiseasedyspneaFatigueDizzinessLightheadednessPalpitationsasenseofimpendingdoomExaminationsofPatientAppearanceskincoloroftheperipheralextremities.Paleorcyanoticskininthelegs,feet,arms,andfingersisassociatedwithpoorcardiovascularfunction.ExaminationsofPatientAppearanceDiagonalearlobecrease.ThisphenomenonhasbeeninvestigatedformanyyearsandrecentlywasonceagainfoundtobehighlypredictiveofheartdiseaseAnthropometricmeasurementsbodyweightfingerpressureonanedematousareaGirthmeasurementsskin-foldcalipermeasurementscalculationofthebodymassindexmeasurethepercentageofbodyfatandleanmusclemassJugularvenousdistensionitisoftenduetoright-sidedheartfailure.PalpationoftheRadialPulsePalpationoftheradialpulsecanprovideimportantinformationaboutthestatusofthecardiovascularsystem.MeasurementoftheSystolicBloodPressureandPulseDuringBreathingandSimplePerturbationsoftheBreathingCycleMeasurementoftheSystolicandDiastolicBloodPressureandPulseinDifferentBodyPositions

ToDeterminetheStatusoftheCardiovascularSystem

observationofadecreaseinsystolicanddiastolicbloodpressurewithoutasubsequentincreaseinheartratewhenchangingbodypositionfromsupinetostandingisconsideredapositivesignforautonomicnervoussystemdysfunction..ToDeterminethe

HealthoftheCardiovascularSystemAcardiovascularsystemthatrespondsrapidlytobodypositionchangeislikelyinabetterstateofhealththanacardiovascularsystemthatrespondssluggishly.Bothanunchangedordecreasedheartrateafterstandingfor30seconds(comparedtotheheartrateat15seconds)issuggestiveofautonomicdysfunction.asluggishorhypoadaptive(lessthannormal)heartrateandbloodpressureresponseduringachangeinbodypositionsupinetostandingshouldbeconsideredabnormalandsuggestiveofanunhealthycardiovascularsystem.amoreadaptiverapidincreaseinheartrateandbloodpressureaftermovingfromasupinetostandingposition(approximately30seconds)islikelyassociatedwithahealthiercardiovascularsystemExaminationofthePulseandArterialBloodPressure

DuringFunctionalTasksandExerciseFrequentmonitoringoftheheartrateandbloodpressuremaybethebestwaytoexaminethesafetyofexerciseandhelptoestablishguidelinesandproceduresforfunctionalorexercisetraining.anincreaseinthediastolicbloodpressurewhenthediastolicbloodpressureshouldbedecreased(orlow)isastrongindicatorofcardiovasculardysfunction..PotentialindirectmeasuresofcardiacfunctionSymptomsandfunctionalclassificationCold,pale,andpossiblycyanoticextremitiesJugularvenousdistensionandperipheraledemaHeartsoundsPulseElectrocardiographyBloodpressureStandardmeasurementofcardiacfunctionCardiaccatheterizationEchocardiographySwan-GanscatheterizationCentralvenouspressureCardiacenzymesANPandBNPRadiologicevidenceLeftmaincoronarystenosisorequivalentModerateaorticvalvular

stenosis(?)ElectrolytedisorderTachyarrhythmiasorBradyarrhythmiasAtrialfibrillationwithuncontrolledventricularresponseHypertrophic

Cardiomyopathy(?gradient)MentalimpairmentleadingtoinabilitytocooperateHigh-degreeAVblockDependencyoncardiacoutputandperipheralresistanceNormalresponses:IncreaseinSBP(>20-30mmHg)NochangeorfallinDBPInadequateriseinSBP:Myocardialischemia,severeLVsystolicdysfunction,aorticorLVOTobstruction,drugtherapy(?-blockers)Exercise-InducedHypotension(>10mmHgbelowbaseline)Severemyocardialischemia(50%positivepredictivevalueforleftmainor3-vesseldisease),valvularheartdisease,cardiomyopathynoevidenceofclinicallysignificantheartdisease(dehydration,antihypertensivetherapy,prolongedstrenuousexercise)AcceleratedHeartRateResponse:Deconditioning,prolongedbedrest,anemia,metabolicdisorders,conditionsassociatedwithdecreasedbloodvolumeorlowsystemicvascularresistance,autonomicinsufficencyChronotropicincompetence:Inadequateexerciseeffort,drugtherapy(?-blockers),PrognosticSignificance:(PeakHR-RestingHR)/(220-age-RestingHR)<0.80(Lauer,1999)PeakHR<130bpm(Ellestad)METcapacity1MET=3.5ml/kg/minO2consumptionFunctionalAerobicImpairment(FAI) (BruceProtocolspecific)PredictedMETlevel(nomograms)PredictedVO2(ACSMformulae)PracticalAspects:LackofassociationbetweenLVEFandexercisecapacityPrognosticvalueofdecreasedexercisecapacityandactiveCADPredictorofpatient’sdisabilityST-segmentelevation(>1.0mm)inleadswithoutQ-waves(otherthanV1oraVR)Dropinsystolicbloodpressure>10mmHg(persistentlybelowbaseline)despiteanincreaseinworkload,whenaccompaniedbyanyotherevidenceofischemiaModeratetosevereangina(grades3-4)Centralnervoussystemsymptoms(ataxia,dizziness,nearsyncope)Signsofpoorperfusion(cyanosisorpallor)SustainedventriculartachycardiaTechnicaldifficultiesmonitoringtheECGorsystolicBPPatient’srequesttostopSTchanges(horizontalordownsloping>2mm)ormarkedaxisshiftDropinsystolicbloodpressure>10mmHg(persistentlybelowbaseline)despiteanincreaseinworkload,intheabsenceofotherevidenceofischemiaandnopresyncopalsymptomsIncreasingchestpainFatigue,shortnessofbreath,wheezing,legcramps,orclaudicationHypertensiveresponse(SBP>250mmHgand/orDBP>115mmHg)Developmentofbundle-branchblock(LBBB)thatcannotbedistinguishedfromventriculartachycardia;?EvidenceofanteriorischemiaArrhythmiasotherthansustainedventriculartachycardia(frequentmultifocalPVC’s,ventriculartriplets,SVT,heartblock,orbradyarrhythmias)GeneralAppearance(diaphoresis,peripheralcyanosis)CriteriaforReadingST-SegmentChangesontheExerciseECGSTDEPRESSION:Measurementsmadeon3consecutiveECGcomplexes!STlevelismeasuredrelativetotheP-Qjunction3keymeasurements(P-Qjunction,J-point,60-80msecafterJ-point-use60msecforHR>130bpmWhenJ-pointisdepressedrelativetoP-Qjunctionatbaseline:NetdifferencefromtheJjunctiondeterminestheamountofdeviationWhentheJ-pointiselevatedrelativetoP-Qjunctionatbaselineandbecomesdepressedwithexercise:MagnitudeofSTdepressionisdeterminedfromtheP-QjunctionandnottherestingJpointCriteriaforReadingST-SegmentChangesontheExerciseECGSTELEVATION:60msecafterJpointin3consecutiveECGcomplexesCriteriaforAbnormalandBorderlineST-SegmentDepressionontheExerciseECGABNORMAL:1.0mmorgreaterhorizontalordownslopingSTdepressionat60msecafterJpointon3consecutiveECGcomplexesBORDERLINE:0.5to1.0mmhorizontalordownslopingSTdepressionat60msecafterJpointon3consecutiveECGcomplexes2.0mmorgreaterupslopingSTdepressionat60msecafterJpointon3consecutiveECGcomplexesMorphologyofST-SegmentDepressionPredictsSeverityofCoronaryArteryDisease

(Goldschlager,1976)Exercise-InducedST-SegmentElevationwithPriorAnteriorMyocardialInfarctionExercise-InducedST-SegmentElevationintheSettingofPriorInferolateralMIExercise-InducedAnteriorST-SegmentElevationasReflectionofLADIschemiaAtypical/PossibleAnginaPectoris:Age30-39Men Intermediate Women VeryLow(<5%)Age40-49 Men Intermediate Women Low(<10%)Age50-50 Men Intermediate Women IntermediateAge60-69 Men Intermediate Women IntermediateNonanginalChestPain:Age30-39 Men Low Women VeryLowAge40-49 Men Intermediate Women VeryLowAge50-59 Men Intermediate Women LowAge60-69 Men Intermediate Women Intermediate

Asymptomatic:Age30-39Men VeryLow Women VeryLowAge40-49Men Low Women VeryLowAge50-59Men Low Women VeryLowAge60-69Men Low Women LowECGAnalysisalone:Sensitivity: 46-79%Specificity: 48-86%UseofDukePrognosticScore:LowRiskscore:19.1%CAD>75%stenosis, 3.5%3-vesselorleftmaindiseaseIntermediateRiskscore:34.9%CAD>75%stenosis,12.4%3-vesselorleftmaindiseaseHighRiskScore:89.2%CAD>75%stenosis,46%3-vesselorleftmaindiseaseClassI:PatientundergoinginitialevaluationwithsuspectedorknownCADincludingthosewithcompleteRBBBandlessthan1mmofrestingECG(exceptions-ClassIIb)PatientswithsuspectedorknowCADpreviouslyevaluated,nowpresentingwithsignificantchangeinclinicalstatusLow-riskacutecoronarysyndromepatients8-12hoursafterpresentationwhohavebeenfreeofactiveischemiaorheartfailuresymptoms(LevelofEvidence=B)Intermediate-riskacutecoronarysyndromepatients2-3daysafterpresentationwhohavebeenfreeofactiveischemiaorheartfailuresymptoms(LevelofEvidence=B)ClassIIa:Intermediate-riskacutecoronarysyndromepatientswhohaveinitialcardiacmarkersthatarenormal,arepeatECGwithoutsignificantchange,andcardiacmarkers6-12hoursaftertheonsetofsymptomsthatarenormalandnootherevidenceofischemiabyobservation(LevelofEvidence=B)ClassIIb:PatientswiththefollowingECGabnormalities:WPWsyndrome,electronicallypacedventricularrhythm,1mmormoreofrestingST-depression,completeLBBBorIVCDwithaQRSduration>120msecPatientswithastableclinicalcoursewhoundergoperiodicmonitoringtoguidetreatmentClassIII:Patientswithsevereco-morbiditylikelytolimitlifeexpectancyand/orcandidacyforrevascularizationHigh-riskacutecoronarysyndromepatients(LevelofEvidence=c)Short-termRiskAssessmentforDeathorNonfatalMIinPatientswithAcuteCoronarySyndrome

HIGHRISK(atleastoneofthefollowingfeatures):CharacterofPain: Prolongedongoing(>20min)restchestpainClinicalFeatures:Pulmonaryedema,neworworseningMR,S3ornew/worseningrales,hypotension,bradycardia,tachycardia,age>75yrsECGFindings:AnginaatrestwithtransientSTchanges>0.05mV,BBB(neworpresumednew),sustainedventriculartachycardiaBiochemicalMarkers:Elevatedtroponin-IShort-termRiskAssessmentforDeathorNonfatalMIinPatientswithAcuteCoronarySyndromeINTERMEDIATERISK:Nohigh-riskfeaturebutmusthaveoneofthefollowing:History:PriorMI,peripheralorcerebrovasculardisease,CABGorprolongedaspirinuseCharacterofPain:Prolonged(>20min)restangina,nowresolved,withmoderatetohighlikelihoodofCADRestangina(<20min)orrelievedbysublingualNTGClinicalFindings:age>70yrsECGFindings:T-waveinversionsgreaterthan0.2mV,pathologicalQ-wavesBiochemicalMarkers:Borderlineelevatedtroponin-IShort-termRiskAssessmentforDeathorNonfatalMIinPatientswithAcuteCoronarySyndromeLOWRISK:Nohighorintermediateriskfeaturesbutanyofthefollowing:CharacterofPain:

New-onsetorprogressiveCCSCIIIorIVanginainpast2weekswithmoderatetohighlikelihoodofCADECGFindings:

NormalorunchangedECGduringanepisodeofchestdiscomfortBiochemicalMarkers:

NormalElectrocardiographic:MaximumST-depressionMaximumST-elevationST-depressionslope(morphology)Num