過(guò)敏性反應(yīng)X亡法醫(yī)病理學(xué)研究 【摘要】目的探討過(guò)敏性反應(yīng)死亡的法醫(yī)病理學(xué)特點(diǎn)，從而解決困擾法醫(yī)學(xué)工作者對(duì)過(guò)敏性反應(yīng)死后診斷的鑒定要點(diǎn)。 方法對(duì)華西法醫(yī)鑒定中心1995-20xx年尸檢檢出的26例藥物過(guò)敏性死亡案例進(jìn)行回顧性分析。結(jié)果本組26例藥物過(guò)敏 所致死亡案例的死者年齡以3140歲的例數(shù)最多，占了38；26例因藥物過(guò)敏所致死亡的案例中，12例為青霉素類藥物過(guò) 敏，為引起過(guò)敏最常見(jiàn)的藥物；而藥物使用途徑引起過(guò)敏反應(yīng)死亡的案例中以注射為主，共20例；以個(gè)體診所及基層醫(yī)院多 發(fā)生過(guò)敏反應(yīng)死亡的案例；18例在使用藥物后出現(xiàn)典型的嚴(yán)重的過(guò)敏性反應(yīng)的臨床表現(xiàn)；15例為在用藥后半小時(shí)內(nèi)發(fā)生死 亡；病理解剖可見(jiàn)咽喉粘膜水腫20例，其中咽喉腔阻塞大于752例，50 755例，25507例，小于256例，顯微鏡下檢 查嗜酸性粒細(xì)胞浸潤(rùn)咽喉粘膜者21例、肺組織18例；6例血清ige檢測(cè)值呈現(xiàn)出顯著的升高。結(jié)論過(guò)敏性反應(yīng)的死后診斷 應(yīng)結(jié)合死者的生前臨床病史，死亡時(shí)間，生前臨床表現(xiàn)，病理解剖發(fā)現(xiàn)及血清lge檢測(cè)值綜合分析。 【關(guān)鍵詞】過(guò)敏性反應(yīng)；法醫(yī)病理學(xué) 【】d9191 f】a 【】10079297(20xx)04029704 the forensic pathological study on death of anaphylaxislln xia yi x ，chen xiao-gang，xie ying guo shao_j；eng the school ofbasical and forensic medicine ofsichuan university chengdu 610041 【abstract】objective to study the characteristics of anaphylaxis in forensic pathology，to clarify the puzzling critic points of the postmortem diagnosismethods data was collected from 26 autopsy cases of anaphylaxis in forensic medical identification center of west china sichuan between 1995 and 20xx results 38 of the cases were between 3 1 and 40 years old the most mon reason resulting in anaphylaxis was penicillin，which cause the anaphylaxis often by injection(20 cases)the alergic cases usually happen at the private clinics and the base hospitals 18 cases have the characteristic symptoms； 15 cases died in 30 min utes after the use of certain drugs th e edema of throat of 20 cases was found in autopsy， thereinto， the block of throat were over 75 in 2 casesbetween 50 and 75 in 5 cases，between 25 and 50 in 7 cases，less than 25 in 6 casesunder the microscopy， the eosinophil were observed in the mucous membrane of throat of 2 1 cases and in the lung of 1 8cases th e serum ige increases notably in 6 cases conclusion th e postmortem diagnosis of anaphylaxis should synchronously consider clinical histo