1、2012級(jí)免疫M(jìn)HC-II提呈外源性抗原的過(guò)程Y什么是T、B細(xì)胞表位，以及他們的區(qū)別Y闡述藥物過(guò)敏性休克的機(jī)制闡述H1N1感染性病毒進(jìn)入機(jī)體的免疫過(guò)程名解MHC, CDR, Vaccine, positive selection in thymus, 自然調(diào)節(jié)性T細(xì)胞，免疫標(biāo)記技術(shù)，填空T,B細(xì)胞的抑制性分子AIRE的易位表達(dá)NK細(xì)胞表面的受體免疫功能粘附分子中樞免疫器官10級(jí)免疫回憶選擇（15*1）1.兄弟之間進(jìn)行移植，起移植反應(yīng)的是下列哪個(gè)抗原？A.同種異型抗原 B.異嗜型抗原 C.異種抗原 D.自身抗原 E.獨(dú)特型抗原2.MHC多態(tài)性提高種群適應(yīng)能力的原因（差不多這個(gè)意思）3.下列哪項(xiàng)是

2、II超敏反應(yīng)的疾病Graves disease4.下列哪個(gè)細(xì)胞因子能使腫瘤出血壞死TNF5.adjuvant的作用 enhance the immunity response of immunogen.6.下列補(bǔ)體成分能跟Fc受體結(jié)合的是 A C3 B C1q C C1r D C1s7.建立tolerance ,you should carry out （） A. intredermal injection of Ag with adjuvant B. intravenous injection of soluble AntigenC. intravenous injection of imm

3、unosuppresstive D. deplete Treg 填空（20*1）1.免疫耐受和免疫應(yīng)答的共同點(diǎn)有，都需要抗原刺激，都有潛伏期和_2.在調(diào)節(jié)細(xì)胞因子時(shí)，Tr1分泌_，Th3分泌_ IL-10 ,TGF-b3.呈遞脂類和脂多糖的是_ CD14.Thymus -independent antigens are antigens which can directly stimulate the B cells to produce antibody without the requirement for _ help in general.5.人體內(nèi)含量最高的Ig是_，能穿過(guò)胎盤(pán)的Ig

4、是_，能分泌于黏膜的是_6.人體中最大的免疫器官是_7.抗原抗體結(jié)合的物質(zhì)基礎(chǔ)是_8.（英文題） MHC 兩類分子結(jié)合抗原肽的部位MHC I_MHC II_ a1,a2; a1,b19.（英文題）B細(xì)胞參與_。主要功能是_，B cell performs a role of _for T cell10.（英文題）免疫球蛋白被胃蛋白酶水解的兩個(gè)片段11、(英文題)TD-Ag 刺激B細(xì)胞產(chǎn)生抗體的過(guò)程需要_的幫助。名解（7*5）1.epitope2.anaphylaxis3.MHC4.negative selection5.人工主動(dòng)免疫6.獨(dú)特型7.酶聯(lián)免疫吸附試驗(yàn)問(wèn)答（3*10）1.T細(xì)胞表面的

5、CD有哪些，在T細(xì)胞介導(dǎo)的免疫應(yīng)答中有哪些作用？2.細(xì)胞因子的共同特點(diǎn)3.描述未成熟DC細(xì)胞和成熟DC細(xì)胞在抗原呈遞和抗原處理的特點(diǎn)（英文）the differences between immature DC and mature DC in processing and presentation09級(jí)名解:1. ITAM2. APC3. CAM4. MHC5. 親和性成熟6. 中樞免疫耐受填空（阿彬提供）1.Papain can cleave an immunoglobulin into _and _ fragments.2.The C3 convertase of classical p

6、athway and alternative pathway is and , respectively.3._with_can induce CD4 T cell to differentiation to the th17 cell.4.the feature of adaptive immune response is_,_and_。5.the immune production to use in artificial active immune including_，_and_。6.超敏反應(yīng)I型的效應(yīng)階段效應(yīng)細(xì)胞包括：_，_和_。7.最常見(jiàn)激活經(jīng)典途徑的補(bǔ)體通路的物質(zhì)是_。 8.通過(guò)

7、胎盤(pán)屏障的Ig是_和黏膜免疫的Ig是_。9.SOCS 通路是靠_通路激活第二信號(hào)的。大題：1. 某病人懷疑為T(mén)細(xì)胞功能障礙，請(qǐng)?jiān)O(shè)計(jì)免疫學(xué)檢測(cè)實(shí)驗(yàn)進(jìn)行確認(rèn)2. 型超敏反應(yīng)的機(jī)制和疾病3. 抗體的功能Please describe the function of the antibody.08級(jí)名解1. Superantigen2. Integrin3. APC4. ELISA5. 胸腺細(xì)胞的陰性選擇6. Treg問(wèn)答：1.超敏I的機(jī)制和疾病2.Th細(xì)胞如何輔助B細(xì)胞進(jìn)行免疫應(yīng)答3.What is MHC, What is Human MHC molecules called, function4

8、.function of Ab07級(jí)名解1. 中樞免疫耐受2. foxP33. MHC4. CAM5. 超抗原6. 免疫標(biāo)記技術(shù)7. positive selection，negative selection問(wèn)答1. 內(nèi)源性抗原的抗原提呈機(jī)制2. 型超敏反應(yīng)機(jī)制及常見(jiàn)病3. 體液免疫應(yīng)答初次、再次的特點(diǎn)05級(jí)名解:1. CAM2. 胸腺細(xì)胞的陰性選擇3. APC4. 交叉提呈5. 可溶性細(xì)胞因子受體(概念和作用)6. TI-AG問(wèn)答題:1. CD4陽(yáng)性T細(xì)胞有哪些亞群,各自的功能是什么?2. 簡(jiǎn)述超敏反應(yīng)發(fā)生的機(jī)制,并列舉兩種疾病.3. 人工主動(dòng)免疫和人工被動(dòng)免疫各有哪些特點(diǎn)?SOCS的信號(hào)通

9、路Hapten Complementarity determining region (CDR)ComplementMHCLeukocyte differentiation antigen APCSomatic hypermutationNegative selectionAnergyRegulatory T cellAICDQuestions:1. Please describe the concepts of TD-Ag and TI-Ag respectively and compare the differences between TD-Ag and TI-Ag.2. Please

10、describe the general properties of cytokine.3. What are the rules of antibody production in vivo? (What are the general features of antibody responses in vivo?)4. Please describe the general process of CD4+ T cell mediated immune response. 5. Please describe the components and pathogenic mechanism involved in